Neuronal and glial cell number is altered in a cortical layer-specific manner in autism

• Published in: Autism : the international journal of research and practice Vol. 25; no. 8; pp. 2238 - 2253
• Main Authors: Falcone, Carmen, Mevises, Natalie-Ya, Hong, Tiffany, Dufour, Brett, Chen, Xiaohui, Noctor, Stephen C., Martínez Cerdeño, Verónica
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.11.2021; SAGE PUBLICATIONS, INC
• Subjects: Adolescents; Adults; Anatomy; Autism; Autism Spectrum Disorder; Autism Spectrum Disorders; Autistic Disorder; Behavior change; Brain; Brain Hemisphere Functions; Brain research; Cell Count; Cerebral Cortex; Children; Circuits; Cortex; Cytology; Differentiation; Entorhinal cortex; Humans; Individualized Instruction; Neuroglia; Neurological Impairments; Neurons; Pathogenesis; Pervasive Developmental Disorders; Prenatal care; Prenatal Influences; Repetitive behaviour; Stem cells; cerebral cortex; anatomy; postmortem; autism

Autism spectrum disorder is a neurodevelopmental condition characterized by impaired social communication and repetitive behaviors. Changes in the number of specific cell types in the cerebral cortex could produce a dramatic alteration in the regulation of cortical circuits, and thus an alteration o...