Complete genome sequence and comparative genome analysis of Streptococcus parauberis KCTC11980

• Published in: Genes & genomics Vol. 37; no. 11; pp. 959 - 968
• Main Authors: Seo, J.S., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Kwon, M.G., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Hwang, J.Y., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Jung, S.H., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Han, H.J., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Kim, M.S., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Do, J.W., National Fisheries Research and Development Institute (NFRDI), Busan, Republic of Korea, Park, M.A., NFRDI, Busan, Republic of Korea, Kim, D.W., Mokweon University, Daejeon, Republic of Korea, Cho, W.S., Mokweon University, Daejeon, Republic of Korea, Lee, K., Konkuk University, Seoul, Republic of Korea
• Format: Journal Article
• Language: English
• Published: Seoul The Genetics Society of Korea 01.11.2015; 한국유전학회
• Subjects: Animal Genetics and Genomics; Biomedical and Life Sciences; cattle; chromosomes; flounder; genes; GENOMAS; GENOME; GENOMES; host-pathogen relationships; Human Genetics; Life Sciences; mastitis; Microbial Genetics and Genomics; mortality; nucleotide sequences; Paralichthys olivaceus; pathogens; phylogeny; physiology; Plant Genetics and Genomics; Pleuronectiformes; Research Article; ribosomal RNA; sequence analysis; Streptococcaceae; Streptococcus parauberis; Streptococcus parauberis,Genome sequence,Fish pathogen,Olive flounder,Paralichthys olivaceus,16S rRNA; udders; 생물학; 16S rRNA; Olive flounder; Genome sequence; Fish pathogen
• ISSN: 1976-9571; 2092-9293
• DOI: 10.1007/s13258-015-0325-y

Streptococcus parauberis is recognized as an alpha-hemolytic gram-positive bacterial pathogen associated with bovine udder mastitis. Recently, S. parauberis was identified as the major pathogen of olive flounder (Paralichthys olivaceus) streptococcosis in Northeast Asia, a disease that causes severe economic losses by triggering massive olive flounder mortality. In this study, the complete genome sequence of S. parauberis KCTC11980 was determined and analyzed. S. parauberis KCTC11980 harbors a single chromosome of 2,179,251 bp containing 2281 predicted coding sequences and featuring an average G?C content of 35.65 %. Dot-plot analysis of the entire genomic sequence and phylogenetic analysis of the 16S rRNA gene revealed a close evolutionary relationship between S. parauberis KCTC11980 and S. uberis. Our findings could serve as a basis for understanding the pathogen-host relationship and developing new prophylactic and therapeutic strategies against fish streptococcosis. This study also enhances our understanding of the physiology and evolution of a key representative of the Streptococcaceae family.