Unilateral methotrexate-induced lung injury with foreign bodies in the airway: A case report

• Published in: Respiratory medicine case reports Vol. 36; p. 101573
• Main Authors: Sakuranaka, Haruyasu, Nakagawa, Takashi, Yokota, Shun, Takahashi, Eichi, Yamakawa, Yuji, Hirata, Akifumi, Igei, Koumei, Okamoto, Naoki, Ichioka, Masahiko
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 2022; Elsevier
• Subjects: Airway foreign body; Case Report; Drug-induced lung injury; Interstitial lung disease; Methotrexate; Pneumonia; Unilateral; Pneumonia; Drug-induced lung injury; Airway foreign body; ILI; BALF; KL-6; DLST; Interstitial lung disease; MTX; CT; T-SPOT.TB; Unilateral; C7HRP; Methotrexate; ILI, induced lung injury; T-SPOT.TB, tuberculosis-specific interferon-γ; BALF, bronchoalveolar lavage fluid; CT, computed tomography; C7HRP, cytomegalovirus pp65 antigen; MTX, methotrexate; KL-6, Krebs von den Lungen 6; DLST, drug lymphocyte stimulation test

A 75-year-old woman who had been taking methotrexate presented to our hospital for fever and dry cough. Chest computed tomography showed ground-glass opacity in the upper lobe of the right lung and foreign bodies in the lower lobe of the right bronchus. During bronchoscopy, foreign bodies were remov...