Training-related brain plasticity in subjects at risk of developing Alzheimer’s disease

• Published in: Brain (London, England : 1878) Vol. 134; no. 6; pp. 1623 - 1634
• Main Authors: Belleville, Sylvie, Clément, Francis, Mellah, Samira, Gilbert, Brigitte, Fontaine, Francine, Gauthier, Serge
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.06.2011
• Subjects: Alzheimer Disease - complications; Alzheimer Disease - rehabilitation; Analysis of Variance; Biological and medical sciences; Brain - blood supply; Brain - physiopathology; Brain Mapping; Case-Control Studies; Cognition Disorders - etiology; Cognition Disorders - pathology; Cognition Disorders - rehabilitation; Cognitive Therapy - methods; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Humans; Image Processing, Computer-Assisted - methods; Magnetic Resonance Imaging - methods; Medical sciences; Neurology; Neuronal Plasticity - physiology; Neuropsychological Tests; Oxygen - blood; Teaching - methods; Human; Nervous system diseases; Cognitive disorder; Alzheimer disease; Memory; Central nervous system; Nuclear magnetic resonance imaging; Cerebral disorder; Encephalon; neuroimaging; memory training; functional MRI; Central nervous system disease; Risk factor; Plasticity; Degenerative disease; mild cognitive impairment; Alzheimer's disease; brain plasticity

Subjects with mild cognitive impairment are at risk of developing Alzheimer's disease. Cognitive stimulation is an emerging intervention in the field of neurology and allied sciences, having already been shown to improve cognition in subjects with mild cognitive impairment. Yet no studies have...