Comparative genome-wide DNA methylation analysis in myocardial tissue from donors with and without Down syndrome - Cejas, Romina B.; Wang, Jie; Hageman-Blair, Rachael; Liu, Song; Blanco, Javier G. (Gene, 2021)
Keywords: Adult; age; Aged; Aged, 80 and over; architecture; Cardiac methylation; Child; Chromosomes, Human, Pair 21 - genetics; Core Binding Factor Alpha 2 Subunit - genetics; CpG Islands - genetics; DNA; DNA Methylation; Down syndrome; Down Syndrome - genetics; Epigenesis, Genetic; Epigenetics; Epigenomics; Female; gender; gene expression; genes; Genetic Loci - genetics; Heart; Humans; Infant; loci; Male; Middle Aged; Myocardium; Myocardium - metabolism; non-coding RNA; people; phenotype; proteins; Real-Time Polymerase Chain Reaction; regression analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - metabolism; sampling; Sequence Analysis, DNA; trisomics; Trisomy 21; variability; Young Adult; Heart; RNA; DMR; GO; mRNA; non-DS; ACTB; DS; RUNX1; Trisomy 21; SNP; FDR; DNA; RRBS; Cardiac methylation; Epigenetics; Myocardium; RT-qPCR; PCR; DSCR