Phospholipase C gene expression, protein content, and activities in cardiac hypertrophy and heart failure due to volume overload

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 287; no. 2; pp. H719 - H727
• Main Authors: Dent, Melissa R, Dhalla, Naranjan S, Tappia, Paramjit S
• Format: Journal Article
• Language: English
• Published: United States 01.08.2004
• Subjects: Animals; Cardiac Output, Low - enzymology; Cardiac Output, Low - etiology; Cardiac Output, Low - physiopathology; Cardiomegaly - enzymology; Cardiomegaly - physiopathology; Cytosol - metabolism; Diglycerides - metabolism; Gene Expression; Hyperemia - complications; Inositol 1,4,5-Trisphosphate - metabolism; Isoenzymes - genetics; Isoenzymes - metabolism; Male; Phosphatidylinositol 4,5-Diphosphate - metabolism; Rats; Rats, Sprague-Dawley; RNA, Messenger - metabolism; Sarcolemma - metabolism; Type C Phospholipases - genetics; Type C Phospholipases - metabolism; Ventricular Function, Left

1 Department of Physiology, Faculty of Medicine; and 2 Department of Human Nutritional Sciences, Faculty of Human Ecology, Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre University of Manitoba, Winnipeg, Manitoba R2H 2A6, Canada Submitted 24 November 2003 ; accepted in f...