Tenascin expression is associated with a chronic inflammatory process in abdominal aortic aneurysms

• Published in: Journal of vascular surgery Vol. 26; no. 4; pp. 670 - 675
• Main Authors: Satta, Jari, Soini, Ylermi, Pöllänen, Raimo, Pääkkö, Paavo, Juvonen, Tatu
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.10.1997; Elsevier
• Subjects: Adult; Aged; Aorta, Abdominal - metabolism; Aortic Aneurysm, Abdominal - metabolism; Aortic Aneurysm, Abdominal - pathology; Aortic Diseases - metabolism; Arterial Occlusive Diseases - metabolism; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Chronic Disease; Diseases of the aorta; Female; Humans; Immunohistochemistry; Inflammation; Male; Medical sciences; Middle Aged; RNA, Messenger - analysis; Tenascin - metabolism; Human; Tenascin; Pathophysiology; Aneurysm; Cardiovascular disease; Exploration; Glycoproteins; Histology; Inflammation; Arterial disease; Vascular disease; Abdominal aorta; Pathology; Chronic; Aortic disease

Purpose: This study was performed to test whether tenascin, a large oligomeric glycoprotein of the extracellular matrix, is present in AAA disease and whether it could play a pathophysiologic role in the development of this disease. Methods: Tenascin immunoreactivity was investigated from samples of...