Stereoselective Metabolism by Human Liver CYP Enzymes of A Substituted Benzimidazole - Äbelö, Angela; Andersson, Tommy B.; Bredberg, Ulf; Skånberg, Inger; Weidolf, Lars (Drug metabolism and disposition, 2000)
Keywords: Anti-Ulcer Agents - chemistry; Anti-Ulcer Agents - metabolism; Aryl Hydrocarbon Hydroxylases; Benzimidazole; Biological and medical sciences; Cells, Cultured; Chromatography, Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System - metabolism; Digestive system; H-259/31; Humans; Medical sciences; Microsomes, Liver - enzymology; Mixed Function Oxygenases - metabolism; Omeprazole - analogs & derivatives; Omeprazole - metabolism; Pharmacology. Drug treatments; Stereoisomerism; Substrate Specificity; EM; CYP; DMSO; PM; LC; AUC; Human; Omeprazole; Stereoselectivity; Benzimidazole derivatives; Analog; Enantiomer; Liver; Structure metabolism relation; Metabolism; In vitro