Polyomaviruses BK, JC, KI, WU, MC, and TS in children with allogeneic hematopoietic stem cell transplantation

• Published in: Pediatric transplantation Vol. 20; no. 3; pp. 424 - 431
• Main Authors: Rahiala, Jaana, Koskenvuo, Minna, Sadeghi, Mohammadreza, Waris, Matti, Vuorinen, Tytti, Lappalainen, Maija, Saarinen-Pihkala, Ulla, Allander, Tobias, Söderlund-Venermo, Maria, Hedman, Klaus, Ruuskanen, Olli, Vettenranta, Kim
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.05.2016
• Subjects: BK Virus; Child; Child, Preschool; childhood; Female; hematopoietic stem cell transplantation; Hematopoietic Stem Cell Transplantation - adverse effects; hemorrhagic cystitis; Humans; Immunocompromised Host; Incidence; Infant; JC Virus; Leukemia - therapy; Male; Medicin och hälsovetenskap; Patient Discharge; Polyomavirus; Polyomavirus Infections - epidemiology; Polyomavirus Infections - immunology; Polyomavirus Infections - virology; Prevalence; Transplantation, Homologous; Tumor Virus Infections - epidemiology; Tumor Virus Infections - immunology; Tumor Virus Infections - virology; Viremia; Young Adult; polyomavirus; hematopoietic stem cell transplantation; hemorrhagic cystitis; childhood

Timely and reliable detection of viruses is of key importance in early diagnosis of infection(s) following allogeneic HSCT. Among the immunocompetent, infections with BKPyV and JCPyV are mostly subclinical, while post‐HSCT, the former may cause HC and the latter PML. The epidemiology and clinical im...