Dried saliva spot as a sampling technique for saliva samples

• Published in: Biomedical chromatography Vol. 28; no. 6; pp. 875 - 877
• Main Authors: Abdel-Rehim, Abbi, Abdel-Rehim, Mohamed
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.06.2014
• Subjects: Anesthetics, Local - analysis; Chromatography, Liquid; dried saliva spot; Humans; LC/MS/MS; lidocaine; Lidocaine - analysis; Mass Spectrometry; saliva; Saliva - chemistry; Specimen Handling - methods; saliva; dried saliva spot; LC/MS/MS; lidocaine

ABSTRACT For the first time, dried saliva spot (DSS) was used as a sampling technique for saliva samples. In the DSS technique 50 μL of saliva was collected on filter paper and the saliva was then extracted with an organic solvent. The local anesthetic lidocaine was used as a model compound, which w...