Circulating Omentin as a Novel Biomarker of Endothelial Dysfunction

• Published in: Obesity (Silver Spring, Md.) Vol. 19; no. 8; pp. 1552 - 1559
• Main Authors: Moreno‐Navarrete, José Maria, Ortega, Francisco, Castro, Antoni, Sabater, Mónica, Ricart, Wifredo, Fernández‐Real, José Manuel
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.08.2011
• Subjects: Adult; Age Factors; Aged; Biomarkers; Biomarkers - blood; Blood Pressure; Blood vessels; Body Composition; Body Mass Index; Brachial Artery - diagnostic imaging; C-Reactive Protein - metabolism; Cytokines - blood; Endothelium, Vascular - diagnostic imaging; Endothelium, Vascular - physiopathology; Enzyme-Linked Immunosorbent Assay; European Continental Ancestry Group; Glucose Intolerance - blood; Glucose Intolerance - complications; Glucose Tolerance Test; GPI-Linked Proteins - blood; Humans; Insulin Resistance; Interleukin-5 - metabolism; Lectins - blood; Linear Models; Male; Middle Aged; Obesity - blood; Obesity - physiopathology; Overweight - blood; Proteins; Reference Values; Risk Factors; Thinness - blood; Ultrasonography; Vascular Diseases - blood; Vascular Diseases - etiology; Vascular Diseases - physiopathology; Vasodilation; Waist-Hip Ratio

Omentin is a novel soluble lectin expressed mainly in the stromal‐vascular cells from visceral adipose tissue with vasodilator effect in isolated blood vessels. To gain insight in the relationship between obesity and cardiovascular risk factors, we aimed to explore the interaction among circulating...