Fluorescent nanoscale detection of biotin–streptavidin interaction using near-field scanning optical microscopy

• Published in: Nanotechnology Vol. 19; no. 23; pp. 235103 - 235103 (7)
• Main Authors: Park, Hyun Kyu, Gokarna, Anisha, Hulme, John P, Park, Hyun Gyu, Chung, Bong Hyun
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 11.06.2008

We describe a nanoscale strategy for detecting biotin-streptavidin binding using near-field scanning optical microscopy (NSOM) that exploits the fluorescence properties of single polydiacetylene (PDA) liposomes. NSOM is more useful to observe nanomaterials having optical properties with the help of...