Current Advances in the Functional Genes of Edible and Medicinal Fungi: Research Techniques, Functional Analysis, and Prospects

Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal fungi, varieties of edible and medicinal fungi can be improved to enhance their agronomic traits, growth rates, and ability to withstand adver...

Full description

Saved in:
Bibliographic Details
Published inJournal of fungi (Basel) Vol. 10; no. 5; p. 311
Main Authors Li, Wenyun, Zou, Gen, Bao, Dapeng, Wu, Yingying
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.05.2024
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal fungi, varieties of edible and medicinal fungi can be improved to enhance their agronomic traits, growth rates, and ability to withstand adversity, thereby increasing yield and quality and promoting industrial development. With the rapid development of functional gene research technology and the publication of many whole-genome sequences of edible and medicinal fungi, genes related to important biological traits have been mined, located, and functionally analyzed. This paper summarizes the advantages and disadvantages of different functional gene research techniques and application examples for edible and medicinal fungi; systematically reviews the research progress of functional genes of edible and medicinal fungi in biological processes such as mating type, mycelium and fruit growth and development, substrate utilization and nutrient transport, environmental response, and the synthesis and regulation of important active substances; and proposes future research directions for functional gene research for edible and medicinal fungi. The overall aim of this study was to provide a valuable reference for further promoting the molecular breeding of edible and medicinal fungi with high yield and quality and to promote the wide application of edible and medicinal fungi products in food, medicine, and industry.
AbstractList Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal fungi, varieties of edible and medicinal fungi can be improved to enhance their agronomic traits, growth rates, and ability to withstand adversity, thereby increasing yield and quality and promoting industrial development. With the rapid development of functional gene research technology and the publication of many whole-genome sequences of edible and medicinal fungi, genes related to important biological traits have been mined, located, and functionally analyzed. This paper summarizes the advantages and disadvantages of different functional gene research techniques and application examples for edible and medicinal fungi; systematically reviews the research progress of functional genes of edible and medicinal fungi in biological processes such as mating type, mycelium and fruit growth and development, substrate utilization and nutrient transport, environmental response, and the synthesis and regulation of important active substances; and proposes future research directions for functional gene research for edible and medicinal fungi. The overall aim of this study was to provide a valuable reference for further promoting the molecular breeding of edible and medicinal fungi with high yield and quality and to promote the wide application of edible and medicinal fungi products in food, medicine, and industry.
Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal fungi, varieties of edible and medicinal fungi can be improved to enhance their agronomic traits, growth rates, and ability to withstand adversity, thereby increasing yield and quality and promoting industrial development. With the rapid development of functional gene research technology and the publication of many whole-genome sequences of edible and medicinal fungi, genes related to important biological traits have been mined, located, and functionally analyzed. This paper summarizes the advantages and disadvantages of different functional gene research techniques and application examples for edible and medicinal fungi; systematically reviews the research progress of functional genes of edible and medicinal fungi in biological processes such as mating type, mycelium and fruit growth and development, substrate utilization and nutrient transport, environmental response, and the synthesis and regulation of important active substances; and proposes future research directions for functional gene research for edible and medicinal fungi. The overall aim of this study was to provide a valuable reference for further promoting the molecular breeding of edible and medicinal fungi with high yield and quality and to promote the wide application of edible and medicinal fungi products in food, medicine, and industry.Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal fungi, varieties of edible and medicinal fungi can be improved to enhance their agronomic traits, growth rates, and ability to withstand adversity, thereby increasing yield and quality and promoting industrial development. With the rapid development of functional gene research technology and the publication of many whole-genome sequences of edible and medicinal fungi, genes related to important biological traits have been mined, located, and functionally analyzed. This paper summarizes the advantages and disadvantages of different functional gene research techniques and application examples for edible and medicinal fungi; systematically reviews the research progress of functional genes of edible and medicinal fungi in biological processes such as mating type, mycelium and fruit growth and development, substrate utilization and nutrient transport, environmental response, and the synthesis and regulation of important active substances; and proposes future research directions for functional gene research for edible and medicinal fungi. The overall aim of this study was to provide a valuable reference for further promoting the molecular breeding of edible and medicinal fungi with high yield and quality and to promote the wide application of edible and medicinal fungi products in food, medicine, and industry.
Audience Academic
Author Li, Wenyun
Bao, Dapeng
Zou, Gen
Wu, Yingying
Author_xml – sequence: 1
  givenname: Wenyun
  orcidid: 0009-0003-4398-1304
  surname: Li
  fullname: Li, Wenyun
– sequence: 2
  givenname: Gen
  orcidid: 0000-0001-5574-1824
  surname: Zou
  fullname: Zou, Gen
– sequence: 3
  givenname: Dapeng
  surname: Bao
  fullname: Bao, Dapeng
– sequence: 4
  givenname: Yingying
  orcidid: 0000-0003-3837-0050
  surname: Wu
  fullname: Wu, Yingying
BackLink https://www.ncbi.nlm.nih.gov/pubmed/38786666$$D View this record in MEDLINE/PubMed
BookMark eNptkt9rFDEQx4NU7A_75LsEfBH0an7sbhLfjqOthYoiFXwL2ezkLsdecia7Qp_815v1Wj1LE0iGyWe-w2TmGB2EGAChV5Scca7Ih3V0lJCacEqfoSPGiZo1RP442LMP0WnOa0IIrWWjFH-BDrkUsinrCP1ejClBGPC8-2WChYx9wMMK8MUY7OBjMD2-hFD80eHzzrc9YBM6_Bk6b_30WsCl_4i_QQaT7ArfgF0F_3OE_H5fZF6O2-yLcwr_mmLegh3yS_TcmT7D6f19gr5fnN8sPs2uv1xeLebXM1tJMcyAtU4KTqrOgXCqaqwiVLVAa97KxgIIYkwHnIjyDEoU0zApXCdbXlDLT9DVTreLZq23yW9MutXReP3HEdNSmzR424OuLaOurkzDbVsBaRVTikLlqkpK4GzServT2qY41Tnojc8W-t4EiGPWnDSEC1Y3tKBvHqHrOKbyFRNVq5pxxup_1NKU_D64OCRjJ1E9F6ou3eKNLNTZE1TZHWy8LWPhfPH_F_D6PvnYbqD7W_VD9wtAd4At7cgJnLZ-MFPDirLvNSV6GjK9N2Ql5t2jmAfZp-g7DGTQHA
CitedBy_id crossref_primary_10_3390_app14188418
crossref_primary_10_1021_acs_jafc_4c06669
crossref_primary_10_33073_pjm_2024_022
crossref_primary_10_3390_jof10120862
crossref_primary_10_3390_jof11030167
Cites_doi 10.3390/jof6040272
10.3389/fimmu.2020.559770
10.1016/j.fgb.2017.04.004
10.1007/s11274-012-1206-z
10.1186/s12934-022-01878-2
10.1016/j.micres.2017.12.015
10.1021/acs.jafc.8b01343
10.3390/jof8020186
10.3389/fmicb.2022.1038034
10.1615/IntJMedMushr.v15.i3.10
10.1038/s41396-023-01432-x
10.1016/j.crfs.2022.100430
10.1007/s10529-016-2064-9
10.1371/journal.pone.0255765
10.1016/j.fgb.2018.07.002
10.1186/s12934-023-02071-9
10.1016/j.ijbiomac.2021.06.122
10.1002/bies.20782
10.3389/fmicb.2020.00577
10.1016/j.jhazmat.2022.129841
10.1016/j.fgb.2020.103415
10.1038/nature.2016.19754
10.3390/molecules27134090
10.1007/s11738-019-2936-4
10.1186/s12974-021-02188-x
10.1615/IntJMedMushrooms.2018026264
10.1111/1462-2920.13693
10.1007/s00253-010-3067-4
10.1007/s00253-010-2690-4
10.1016/j.ijbiomac.2019.05.043
10.1007/s00253-018-9226-8
10.1128/mbio.00628-22
10.1016/j.postharvbio.2021.111784
10.1016/j.procbio.2017.02.012
10.1128/aem.00940-22
10.1016/j.foodres.2022.112090
10.3389/fmicb.2021.698436
10.1038/s41598-017-00483-3
10.1039/D1GC03594K
10.1016/j.scienta.2022.111417
10.1002/bit.26583
10.1016/j.gene.2021.145618
10.3390/life13030764
10.1002/bit.27154
10.1186/s12934-023-02213-z
10.1016/j.fgb.2013.08.007
10.1016/j.carbpol.2018.08.021
10.3389/fmicb.2023.1139679
10.1007/s11033-011-1431-9
10.1615/IntJMedMushrooms.2022044442
10.1007/s00449-014-1279-1
10.1016/j.scitotenv.2023.161807
10.1093/femsle/fnad015
10.1007/s00203-021-02514-0
10.3389/fmicb.2021.815954
10.3390/jof8101000
10.3390/jof8040401
10.2174/092986710791698495
10.1016/j.ijbiomac.2020.09.239
10.3390/foods10010095
10.3390/jof8060581
10.1016/j.funbio.2018.12.008
10.1038/s41598-017-00883-5
10.1007/s00253-021-11564-9
10.1016/j.mtbio.2023.100560
10.1186/s12934-019-1164-3
10.1016/j.myc.2019.06.004
10.1016/j.micres.2015.06.005
10.1016/j.scienta.2018.08.043
10.1128/AEM.00156-21
10.1128/EC.00319-09
10.1093/femsle/fnad036
10.1016/j.ijbiomac.2023.126778
10.1007/s11274-018-2529-1
10.1099/mic.0.000527
10.1128/AEM.01263-12
10.1021/acs.jafc.9b03569
10.1016/j.drudis.2018.09.014
10.1016/j.ymben.2019.09.009
10.1016/j.heliyon.2023.e16682
10.1016/j.jbiosc.2012.10.020
10.3390/molecules26216708
10.1016/j.fct.2018.12.036
10.1016/j.tibtech.2022.10.001
10.1016/j.biortech.2022.126792
10.2307/1293845
10.1007/s00253-021-11175-4
10.1155/2019/3139689
10.1038/166949a0
10.3389/fimmu.2022.1034545
10.1016/j.chembiol.2017.09.001
10.1007/s00253-019-10074-z
10.3390/ijms24054864
10.1128/MMBR.62.1.55-70.1998
10.3389/fbioe.2021.796278
10.1016/j.bcab.2021.102163
10.1016/j.scienta.2022.111623
10.1128/AEM.01735-19
10.1016/j.intimp.2023.109759
10.1016/j.jbiotec.2015.11.011
10.1016/j.jbiotec.2013.09.013
10.1016/j.ijbiomac.2020.02.083
10.1016/j.synbio.2023.03.003
10.1111/1751-7915.13652
10.1016/j.mimet.2018.07.006
10.1016/j.fbio.2023.102486
10.1111/1462-2920.13350
10.1128/AEM.01036-16
10.1128/mbio.03626-21
10.1016/j.foodres.2021.110452
10.3389/fmicb.2021.724451
10.1016/j.myc.2014.05.005
10.1007/s00253-020-10707-8
10.1007/s00253-021-11717-w
10.3390/genes10060467
10.1016/j.phytochem.2021.112677
10.1038/s41467-022-35500-1
10.1016/j.tifs.2019.08.009
10.1016/j.tifs.2023.01.006
10.5941/MYCO.2015.43.3.327
10.3390/genes13061080
10.3389/fmicb.2018.02944
10.1111/1751-7915.14147
10.1007/s00253-023-12726-7
10.3390/nu14112268
10.1016/j.fshw.2021.04.003
10.3390/ijms20246116
10.1016/j.ijbiomac.2022.11.037
10.1016/j.synbio.2022.02.002
10.1016/j.phytochem.2023.113791
10.1007/s00438-018-01528-6
10.1007/s11274-017-2378-3
10.1007/s00253-019-10016-9
10.1021/acs.jcim.6b00087
10.1016/j.biortech.2020.124119
10.1016/j.mimet.2020.105878
10.47371/mycosci.2020.11.008
10.1111/j.1467-3010.2010.01859.x
10.1111/1541-4337.12708
10.3390/molecules28124796
10.1016/j.ijbiomac.2023.124648
10.1038/s41929-022-00762-x
10.1111/1462-2920.14826
10.1007/s00253-022-12066-y
10.1016/j.mimet.2018.07.018
10.1111/j.1469-8137.1949.tb05120.x
10.1016/j.biortech.2023.128888
10.3389/fmicb.2020.00498
10.1016/j.ijbiomac.2020.06.139
10.1016/j.postharvbio.2021.111786
10.1007/s00253-018-9022-5
10.1002/cbic.202300008
10.3390/jof9100959
10.3389/fmicb.2018.01157
10.1007/s11274-019-2741-7
10.1016/j.enzmictec.2023.110254
10.1016/j.phytochem.2022.113131
10.1016/j.bcdf.2013.01.002
10.1038/s41598-019-44133-2
10.1016/j.ijbiomac.2023.124291
10.1186/s12934-023-02025-1
10.3389/fmicb.2022.878110
10.1007/s00253-019-10298-z
10.1007/s00253-021-11734-9
10.1111/1751-7915.14107
10.3389/fmicb.2020.01038
10.1155/2014/805841
10.1016/j.intimp.2022.108695
10.1111/1751-7915.13534
10.3390/jof9040412
10.3390/ijms24054586
10.1002/jobm.201500752
10.1007/978-1-0716-1048-0_8
10.4489/MYCO.2010.38.4.331
10.1128/spectrum.05272-22
10.3390/jof9060688
10.1371/journal.pone.0230680
10.1016/j.ijbiomac.2021.12.178
10.1016/j.myc.2012.09.002
10.1007/s00253-016-7574-9
10.1111/1574-6968.12393
10.3390/ijms24098143
10.1021/acs.jnatprod.5b00020
10.1016/j.jfutfo.2022.01.002
10.1007/s00253-020-10951-y
10.3389/fmicb.2022.1009885
10.3390/ijms17121884
10.1016/j.myc.2017.09.001
10.1016/j.myc.2019.02.004
10.1016/j.procbio.2021.11.024
10.1016/j.procbio.2017.05.029
10.1016/j.funbio.2018.10.008
10.3389/fmicb.2023.1169884
10.1111/1462-2920.15400
10.1016/j.gene.2019.04.067
10.1016/j.funbio.2018.12.007
10.1007/s00253-020-10642-8
ContentType Journal Article
Copyright COPYRIGHT 2024 MDPI AG
2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: COPYRIGHT 2024 MDPI AG
– notice: 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID AAYXX
CITATION
NPM
8FE
8FH
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
COVID
DWQXO
GNUQQ
HCIFZ
LK8
M7P
PHGZM
PHGZT
PIMPY
PKEHL
PQEST
PQGLB
PQQKQ
PQUKI
7X8
DOA
DOI 10.3390/jof10050311
DatabaseName CrossRef
PubMed
ProQuest SciTech Collection
ProQuest Natural Science Collection
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
ProQuest One Community College
Coronavirus Research Database
ProQuest Central Korea
ProQuest Central Student
SciTech Premium Collection
ProQuest Biological Science Collection
Biological Science Database
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
MEDLINE - Academic
DOAJ Directory of Open Access Journals (ODIN)
DatabaseTitle CrossRef
PubMed
Publicly Available Content Database
ProQuest Central Student
ProQuest One Academic Middle East (New)
ProQuest Biological Science Collection
ProQuest Central Essentials
ProQuest One Academic Eastern Edition
Coronavirus Research Database
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest Natural Science Collection
Biological Science Database
ProQuest SciTech Collection
ProQuest Central
ProQuest One Applied & Life Sciences
ProQuest One Academic UKI Edition
Natural Science Collection
ProQuest Central Korea
Biological Science Collection
ProQuest Central (New)
ProQuest One Academic
ProQuest One Academic (New)
MEDLINE - Academic
DatabaseTitleList

CrossRef
MEDLINE - Academic
PubMed
Publicly Available Content Database
Database_xml – sequence: 1
  dbid: DOA
  name: Directory of Open Access Journals (DOAJ)
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Botany
EISSN 2309-608X
ExternalDocumentID oai_doaj_org_article_5c21f54a63cb4e0b92991e4f4488e32c
A795387368
38786666
10_3390_jof10050311
Genre Journal Article
Review
GeographicLocations China
GeographicLocations_xml – name: China
GrantInformation_xml – fundername: Excellent Team Plan of Shanghai Academy of Agricultural Sciences
  grantid: (2022)014
– fundername: Shanghai Agriculture Applied Technology Development Program, China
  grantid: (Grant No. X2022-02-08-00-12-F01137)
GroupedDBID 53G
5VS
8FE
8FH
AADQD
AAFWJ
AAHBH
AAYXX
ABDBF
ACUHS
ADBBV
AFKRA
AFPKN
AFZYC
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BBNVY
BCNDV
BENPR
BHPHI
CCPQU
CITATION
GROUPED_DOAJ
HCIFZ
HYE
IAO
ITC
KQ8
LK8
M7P
MODMG
M~E
OK1
OZF
PGMZT
PHGZM
PHGZT
PIMPY
PROAC
RPM
NPM
PMFND
ABUWG
AZQEC
COVID
DWQXO
GNUQQ
PKEHL
PQEST
PQGLB
PQQKQ
PQUKI
7X8
PUEGO
ID FETCH-LOGICAL-c487t-e2bf87304dfe7f946c9019be153b86cee70aade307e7fe97de3a287fd8b3c90c3
IEDL.DBID BENPR
ISSN 2309-608X
IngestDate Wed Aug 27 01:25:10 EDT 2025
Fri Jul 11 15:41:23 EDT 2025
Fri Jul 25 11:54:11 EDT 2025
Tue Jun 17 22:13:34 EDT 2025
Tue Jun 10 21:08:43 EDT 2025
Thu Apr 03 06:56:58 EDT 2025
Tue Jul 01 03:31:13 EDT 2025
Thu Apr 24 23:08:13 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 5
Keywords active substances
macrofungi
genetic transformation
gene editing
mating-type genes
Language English
License https://creativecommons.org/licenses/by/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c487t-e2bf87304dfe7f946c9019be153b86cee70aade307e7fe97de3a287fd8b3c90c3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ORCID 0000-0001-5574-1824
0000-0003-3837-0050
0009-0003-4398-1304
OpenAccessLink https://www.proquest.com/docview/3059523225?pq-origsite=%requestingapplication%
PMID 38786666
PQID 3059523225
PQPubID 2059559
ParticipantIDs doaj_primary_oai_doaj_org_article_5c21f54a63cb4e0b92991e4f4488e32c
proquest_miscellaneous_3060372561
proquest_journals_3059523225
gale_infotracmisc_A795387368
gale_infotracacademiconefile_A795387368
pubmed_primary_38786666
crossref_citationtrail_10_3390_jof10050311
crossref_primary_10_3390_jof10050311
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2024-05-01
PublicationDateYYYYMMDD 2024-05-01
PublicationDate_xml – month: 05
  year: 2024
  text: 2024-05-01
  day: 01
PublicationDecade 2020
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Basel
PublicationTitle Journal of fungi (Basel)
PublicationTitleAlternate J Fungi (Basel)
PublicationYear 2024
Publisher MDPI AG
Publisher_xml – name: MDPI AG
References ref_94
ref_137
ref_258
ref_93
Shioya (ref_156) 2013; 58–59
Bao (ref_255) 2017; 33
Sharma (ref_219) 2022; 24
Deng (ref_216) 2022; 107
Wasser (ref_8) 2011; 89
ref_96
ref_134
Hou (ref_135) 2022; 21
Jiang (ref_236) 2022; 106
ref_126
ref_247
ref_127
ref_129
Zou (ref_107) 2021; 2234
Wang (ref_254) 2016; 56
Zhang (ref_195) 2022; 198
Tao (ref_136) 2019; 706
Hu (ref_53) 2018; 58
ref_241
Wang (ref_146) 2020; 39
ref_240
Yu (ref_88) 2016; 38
ref_243
ref_242
ref_245
Yang (ref_98) 2021; 37
Han (ref_141) 2018; 25
Qian (ref_125) 2021; 37
Shi (ref_44) 2014; 33
Zhang (ref_155) 2015; 179
Shi (ref_206) 2017; 163
Kim (ref_43) 2010; 38
ref_71
ref_158
ref_70
Xu (ref_120) 2020; 39
Zhao (ref_194) 2023; 213
Rezvani (ref_249) 2020; 104
ref_151
Wei (ref_217) 2021; 18
ref_153
Liu (ref_171) 2022; 199
Xia (ref_223) 2017; 24
Ding (ref_97) 2023; 22
ref_75
Raudaskoski (ref_118) 2010; 9
Zhou (ref_159) 2016; 35
Lee (ref_105) 2023; 168
Waltz (ref_80) 2016; 532
Riffiani (ref_128) 2021; 62
Tu (ref_147) 2021; 28
Zhang (ref_154) 2021; 105
Fei (ref_203) 2019; 18
Zhu (ref_24) 2022; 223
Sun (ref_122) 2023; 42
Cui (ref_235) 2019; 67
Qi (ref_62) 2019; 123
Zhang (ref_209) 2021; 105
Shi (ref_204) 2012; 39
Bao (ref_14) 2021; 40
Feng (ref_113) 2023; 42
Zou (ref_228) 2021; 23
ref_142
ref_86
Zhang (ref_47) 2017; 15
ref_85
Meng (ref_87) 2022; 15
Sun (ref_168) 2023; 107
Ma (ref_123) 2022; 29
Pelkmans (ref_183) 2017; 7
Yang (ref_179) 2021; 48
Cao (ref_21) 2023; 6
Ma (ref_55) 2018; 37
Bao (ref_121) 2019; 38
Gao (ref_257) 2019; 2019
Pelkmans (ref_157) 2016; 100
Su (ref_130) 2017; 36
Zeng (ref_29) 2022; 162
Jiang (ref_64) 2017; 36
Yang (ref_104) 2022; 22
Zhou (ref_218) 2023; 116
Zhao (ref_220) 2020; 36
Zhang (ref_150) 2017; 104
Wang (ref_234) 2021; 147
Yun (ref_144) 2015; 43
Ren (ref_202) 2013; 29
ref_207
Liu (ref_74) 2021; 184
Zhao (ref_132) 2023; 30
Li (ref_37) 2021; 37
Gong (ref_52) 2022; 305
ref_200
Casselton (ref_119) 1998; 62
Tan (ref_197) 2019; 26
He (ref_199) 2023; 15
ref_116
Elsayed (ref_191) 2014; 2014
ref_230
ref_112
Wu (ref_252) 2020; 11
Lin (ref_23) 2021; 80
Jiang (ref_205) 2018; 25
Shang (ref_67) 2019; 60
Fang (ref_59) 2013; 54
ref_225
ref_224
Chen (ref_161) 2018; 37
ref_227
ref_226
Bao (ref_152) 2018; 59
Wang (ref_192) 2023; 9
Wang (ref_54) 2018; 118
Shen (ref_78) 2017; 43
Shang (ref_76) 2018; 152
Kurahashi (ref_186) 2015; 56
Yang (ref_182) 2014; 352
Wang (ref_162) 2019; 123
Zhang (ref_6) 2021; 10
Shen (ref_20) 2022; 49
Wu (ref_201) 2013; 15
Wang (ref_102) 2018; 115
Du (ref_66) 2021; 40
Zhu (ref_212) 2021; 23
Zhang (ref_83) 2023; 30
Ge (ref_89) 2017; 2
Zhou (ref_253) 2018; 102
Mingyi (ref_3) 2019; 92
ref_10
Gu (ref_198) 2017; 60
ref_19
Whitehouse (ref_115) 1949; 48
Cheung (ref_1) 2010; 35
ref_18
Chen (ref_189) 2020; 39
ref_17
Li (ref_170) 2019; 134
Escobar (ref_90) 2019; 9
Liu (ref_39) 2014; 33
Duan (ref_221) 2023; 132
Zan (ref_237) 2020; 161
ref_25
Shang (ref_124) 2020; 39
Yu (ref_92) 2022; 7
Long (ref_143) 2018; 47
ref_22
Yuan (ref_109) 2022; 13
Lyu (ref_138) 2021; 203
Chen (ref_160) 2020; 39
Heneghan (ref_175) 2016; 18
Wu (ref_140) 2020; 104
Zhang (ref_244) 2013; 1
Zhou (ref_233) 2018; 66
ref_28
ref_27
Hu (ref_229) 2018; 200
Bisen (ref_232) 2010; 17
ref_26
Yan (ref_163) 2018; 34
Chen (ref_46) 2023; 42
Li (ref_251) 2021; 61
Chen (ref_110) 2022; 15
Lou (ref_63) 2019; 103
Liu (ref_58) 2017; 19
Nakazawa (ref_133) 2019; 123
Ye (ref_259) 2022; 106
Li (ref_9) 2021; 20
Li (ref_248) 2019; 24
Zhong (ref_56) 2021; 28
Xu (ref_246) 2022; 13
Liu (ref_82) 2020; 13
Xu (ref_238) 2015; 38
Qin (ref_81) 2017; 56
Wu (ref_148) 2016; 108
Hu (ref_188) 2019; 41
Zan (ref_167) 2020; 165
Yuan (ref_214) 2022; 5
Xu (ref_95) 2019; 26
Meng (ref_48) 2021; 785
Sato (ref_164) 2019; 60
Zhao (ref_15) 2021; 19
ref_50
Lan (ref_108) 2019; 116
Zhu (ref_166) 2016; 56
Li (ref_185) 2023; 309
Wu (ref_139) 2019; 85
ref_173
ref_172
Drott (ref_16) 2023; 17
ref_174
Tan (ref_222) 2023; 8
ref_176
ref_51
ref_178
Bai (ref_103) 2020; 150
Shen (ref_190) 2022; 440
Sugano (ref_84) 2017; 7
Zou (ref_12) 2023; 41
Sekiya (ref_49) 2013; 115
Lin (ref_61) 2015; 78
Zhang (ref_149) 2018; 207
Liu (ref_69) 2015; 22
Li (ref_100) 2019; 46
ref_169
Shangguan (ref_36) 2019; 17
Guo (ref_114) 2022; 20
ref_65
Wang (ref_79) 2020; 104
ref_165
Zha (ref_77) 2020; 27
Yang (ref_181) 2020; 39
Xu (ref_60) 2012; 78
Lou (ref_40) 2019; 243
Liu (ref_68) 2018; 152
Li (ref_239) 2016; 217
Lian (ref_177) 2023; 22
Zhang (ref_42) 2015; 23
ref_35
Adams (ref_99) 2019; 56
Ye (ref_13) 2023; 869
ref_34
ref_33
ref_196
ref_32
ref_31
ref_30
Zou (ref_91) 2021; 14
Han (ref_111) 2023; 22
Yang (ref_180) 2020; 27
Zhang (ref_210) 2016; 82
Bao (ref_256) 2018; 20
Wong (ref_4) 2010; 87
ref_38
Lin (ref_250) 2013; 168
Wang (ref_213) 2022; 106
Yang (ref_231) 2019; 125
Shen (ref_131) 2015; 22
Cunningham (ref_215) 1950; 166
Yin (ref_5) 2021; 1
Dong (ref_106) 2012; 52
Hu (ref_208) 2020; 22
Herzog (ref_72) 2019; 294
ref_184
ref_45
Wang (ref_73) 2019; 103
Shi (ref_211) 2020; 104
ref_187
ref_41
ref_2
Grimm (ref_11) 2018; 102
Ahmad (ref_193) 2021; 187
Liu (ref_145) 2022; 49
Wang (ref_57) 2019; 26
Casselton (ref_117) 2008; 30
ref_7
Liang (ref_101) 2022; 112
References_xml – ident: ref_187
  doi: 10.3390/jof6040272
– volume: 11
  start-page: 559770
  year: 2020
  ident: ref_252
  article-title: Identification and Functional Characterization of a Novel Immunomodulatory Protein From Morchella conica SH
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.559770
– volume: 104
  start-page: 6
  year: 2017
  ident: ref_150
  article-title: The mitogen-activated protein kinase GlSlt2 regulates fungal growth, fruiting body development, cell wall integrity, oxidative stress and ganoderic acid biosynthesis in Ganoderma lucidum
  publication-title: Fungal Genet. Biol.
  doi: 10.1016/j.fgb.2017.04.004
– volume: 26
  start-page: 161
  year: 2019
  ident: ref_57
  article-title: Functional Analyses of Tryptophan Synthase Gene LetrpB in Lentinula edodes by RNAi Method
  publication-title: Acta Edulis Fungi
– volume: 29
  start-page: 523
  year: 2013
  ident: ref_202
  article-title: Molecular characterization and expression analysis of GlHMGS, a gene encoding hydroxymethylglutaryl-CoA synthase from Ganoderma lucidum (Ling-zhi) in ganoderic acid biosynthesis pathway
  publication-title: World J. Microb. Biot.
  doi: 10.1007/s11274-012-1206-z
– volume: 21
  start-page: 155
  year: 2022
  ident: ref_135
  article-title: Mnsod1 promotes the development of Pleurotus ostreatus and enhances the tolerance of mycelia to heat stress
  publication-title: Microb. Cell Fact.
  doi: 10.1186/s12934-022-01878-2
– volume: 207
  start-page: 280
  year: 2018
  ident: ref_149
  article-title: Functional analysis of an APSES transcription factor (GlSwi6) involved in fungal growth, fruiting body development and ganoderic-acid biosynthesis in Ganoderma lucidum
  publication-title: Microbiol. Res.
  doi: 10.1016/j.micres.2017.12.015
– volume: 66
  start-page: 4702
  year: 2018
  ident: ref_233
  article-title: Improved Polysaccharide Production by Homologous Co-overexpression of Phosphoglucomutase and UDP Glucose Pyrophosphorylase Genes in the Mushroom Coprinopsis cinerea
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.8b01343
– ident: ref_75
  doi: 10.3390/jof8020186
– ident: ref_184
  doi: 10.3389/fmicb.2022.1038034
– volume: 15
  start-page: 223
  year: 2013
  ident: ref_201
  article-title: The cloning, characterization, and functional analysis of a gene encoding an isopentenyl diphosphate isomerase involved in triterpene biosynthesis in the Lingzhi or reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes)
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushr.v15.i3.10
– volume: 15
  start-page: 376
  year: 2023
  ident: ref_199
  article-title: Germplasm resources and secondary metabolism regulation in Reishi mushroom (Ganoderma lucidum)
  publication-title: Chin. Herb. Med.
– volume: 20
  start-page: 4067
  year: 2022
  ident: ref_114
  article-title: Application of Mating Type Gene Molecular Markers in Morchella Single-spore Cross Breeding
  publication-title: Mol. Plant Breed.
– volume: 17
  start-page: 1236
  year: 2023
  ident: ref_16
  article-title: Pangenomics of the death cap mushroom Amanita phalloides, and of Agaricales, reveals dynamic evolution of toxin genes in an invasive range
  publication-title: ISME J.
  doi: 10.1038/s41396-023-01432-x
– volume: 6
  start-page: 100430
  year: 2023
  ident: ref_21
  article-title: Application of omics technology in the research on edible fungi
  publication-title: Curr. Res. Food Sci.
  doi: 10.1016/j.crfs.2022.100430
– volume: 38
  start-page: 919
  year: 2016
  ident: ref_88
  article-title: Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAX
  publication-title: Biotechnol. Lett.
  doi: 10.1007/s10529-016-2064-9
– ident: ref_31
  doi: 10.1371/journal.pone.0255765
– volume: 118
  start-page: 37
  year: 2018
  ident: ref_54
  article-title: The heat shock protein 40 LeDnaJ regulates stress resistance and indole-3-acetic acid biosynthesis in Lentinula edodes
  publication-title: Fungal Genet. Biol.
  doi: 10.1016/j.fgb.2018.07.002
– volume: 22
  start-page: 60
  year: 2023
  ident: ref_111
  article-title: High-efficient production of mushroom polyketide compounds in a platform host Aspergillus oryzae
  publication-title: Microb. Cell Fact.
  doi: 10.1186/s12934-023-02071-9
– volume: 187
  start-page: 769
  year: 2021
  ident: ref_193
  article-title: Ganoderma lucidum: A potential source to surmount viral infections through β-glucans immunomodulatory and triterpenoids antiviral properties
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2021.06.122
– volume: 26
  start-page: 125
  year: 2019
  ident: ref_197
  article-title: Current Progress in the Study on Biosynthesisand Regulation of Ganoderma Triterpenoids
  publication-title: Acta Edulis Fungi
– volume: 30
  start-page: 711
  year: 2008
  ident: ref_117
  article-title: Fungal sex genes-searching for the ancestors
  publication-title: BioEssays News Rev. Mol. Cell. Dev. Biol.
  doi: 10.1002/bies.20782
– ident: ref_226
  doi: 10.3389/fmicb.2020.00577
– volume: 440
  start-page: 129841
  year: 2022
  ident: ref_190
  article-title: Molecular mechanism underlying cadmium tolerance differentiation in Lentinula edodes as revealed by mRNA and milRNA analyses
  publication-title: J. Hazard. Mater.
  doi: 10.1016/j.jhazmat.2022.129841
– ident: ref_225
  doi: 10.1016/j.fgb.2020.103415
– volume: 80
  start-page: 153384
  year: 2021
  ident: ref_23
  article-title: Functional proteomic analysis reveals that fungal immunomodulatory protein reduced expressions of heat shock proteins correlates to apoptosis in lung cancer cells
  publication-title: Phytomed. Int. J. Phytother. Phytopharm.
– volume: 532
  start-page: 293
  year: 2016
  ident: ref_80
  article-title: Gene-edited CRISPR mushroom escapes US regulation
  publication-title: Nature
  doi: 10.1038/nature.2016.19754
– ident: ref_245
  doi: 10.3390/molecules27134090
– volume: 41
  start-page: 160
  year: 2019
  ident: ref_188
  article-title: Para-aminobenzoic acid synthase from mushroom Agaricus bisporus enhances UV-C tolerance in Arabidopsis by reducing oxidative DNA damage
  publication-title: Acta Physiol. Plant.
  doi: 10.1007/s11738-019-2936-4
– volume: 18
  start-page: 137
  year: 2021
  ident: ref_217
  article-title: Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury
  publication-title: J. Neuroinflamm.
  doi: 10.1186/s12974-021-02188-x
– volume: 20
  start-page: 537
  year: 2018
  ident: ref_256
  article-title: Computational Insights into the Molecular Mechanism of the High Immunomodulatory Activity of LZ-8 Protein Isolated from the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes)
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.2018026264
– volume: 19
  start-page: 1653
  year: 2017
  ident: ref_58
  article-title: Membrane fluidity is involved in the regulation of heat stress induced secondary metabolism in Ganoderma lucidum
  publication-title: Environ. Microbiol.
  doi: 10.1111/1462-2920.13693
– volume: 89
  start-page: 1323
  year: 2011
  ident: ref_8
  article-title: Current findings, future trends, and unsolved problems in studies of medicinal mushrooms
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-010-3067-4
– volume: 87
  start-page: 1221
  year: 2010
  ident: ref_4
  article-title: Proteins with antifungal properties and other medicinal applications from plants and mushrooms
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-010-2690-4
– volume: 134
  start-page: 146
  year: 2019
  ident: ref_170
  article-title: Expression of a recombinant Lentinula edodes cellobiohydrolase by Pichia pastoris and its effects on in vitro ruminal fermentation of agricultural straws
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2019.05.043
– volume: 102
  start-page: 7795
  year: 2018
  ident: ref_11
  article-title: Mushroom cultivation in the circular economy
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-018-9226-8
– volume: 37
  start-page: 1637
  year: 2021
  ident: ref_37
  article-title: Advances in metabolic engineering of filamentous fungi
  publication-title: Chin. J. Biotechnol.
– ident: ref_32
  doi: 10.1128/mbio.00628-22
– volume: 37
  start-page: 874
  year: 2021
  ident: ref_98
  article-title: Progress and perspective on development of non-model industrial bacteria as chassis cells for biochemical productionin the synthetic biology era
  publication-title: Chin. J. Biotechnol.
– ident: ref_34
  doi: 10.1016/j.postharvbio.2021.111784
– volume: 56
  start-page: 57
  year: 2017
  ident: ref_81
  article-title: CRISPR-Cas9 assisted gene disruption in the higher fungus Ganoderma species
  publication-title: Process Biochem.
  doi: 10.1016/j.procbio.2017.02.012
– ident: ref_178
  doi: 10.1128/aem.00940-22
– volume: 162
  start-page: 112090
  year: 2022
  ident: ref_29
  article-title: Metabolomic analysis provides insights into the mechanism of color and taste changes in Dictyophora indusiata fruiting bodies under different drying processes
  publication-title: Food Res. Int.
  doi: 10.1016/j.foodres.2022.112090
– ident: ref_227
  doi: 10.3389/fmicb.2021.698436
– volume: 38
  start-page: 2061
  year: 2019
  ident: ref_121
  article-title: Research progress on the mating-typing locus structures of basidiomycete mushrooms
  publication-title: Mycosystema
– volume: 7
  start-page: 310
  year: 2017
  ident: ref_183
  article-title: Transcription factors of Schizophyllum commune involved in mushroom formation and modulation of vegetative growth
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-017-00483-3
– volume: 33
  start-page: 121
  year: 2014
  ident: ref_39
  article-title: Establishment of genetic transformation system of Hericium erinaceus using PEG mediated method
  publication-title: Mycosystema
– volume: 23
  start-page: 10030
  year: 2021
  ident: ref_228
  article-title: Efficient conversion of spent mushroom substrate into a high value-added anticancer drug pentostatin with engineered Cordyceps militaris
  publication-title: Green Chem.
  doi: 10.1039/D1GC03594K
– volume: 305
  start-page: 111417
  year: 2022
  ident: ref_52
  article-title: QTL mapping reveals mating type gene LeHD1 regulating mycelial growth in shiitake mushroom, Lentinula edodes
  publication-title: Sci. Hortic.
  doi: 10.1016/j.scienta.2022.111417
– volume: 115
  start-page: 1842
  year: 2018
  ident: ref_102
  article-title: Biosynthesis of a ganoderic acid in Saccharomyces cerevisiae by expressing a cytochrome P450 gene from Ganoderma lucidum
  publication-title: Biotechnol. Bioeng.
  doi: 10.1002/bit.26583
– volume: 785
  start-page: 145618
  year: 2021
  ident: ref_48
  article-title: The transcription factor FvHmg1 negatively regulates fruiting body development in Winter Mushroom Flammulina velutipes
  publication-title: Gene
  doi: 10.1016/j.gene.2021.145618
– ident: ref_153
  doi: 10.3390/life13030764
– volume: 116
  start-page: 3301
  year: 2019
  ident: ref_108
  article-title: Efficient biosynthesis of antitumor ganoderic acid HLDOA using a dual tunable system for optimizing the expression of CYP5150L8 and a Ganoderma P450 reductase
  publication-title: Biotechnol. Bioeng.
  doi: 10.1002/bit.27154
– volume: 19
  start-page: 271
  year: 2021
  ident: ref_15
  article-title: Sequencing and Analysis of the Whole Genome of Morchella importuna MT1
  publication-title: J. Fungal Res.
– volume: 27
  start-page: 105
  year: 2020
  ident: ref_77
  article-title: Research Progress on Agrobacterium mediated Transformation of Edible Fungi
  publication-title: Acta Edulis Fungi
– volume: 22
  start-page: 205
  year: 2023
  ident: ref_177
  article-title: The transcription factor GCN4 contributes to maintaining intracellular amino acid contents under nitrogen-limiting conditions in the mushroom Ganoderma lucidum
  publication-title: Microb. Cell Factories
  doi: 10.1186/s12934-023-02213-z
– volume: 58–59
  start-page: 80
  year: 2013
  ident: ref_156
  article-title: The Coprinopsis cinerea septin Cc.Cdc3 is involved in stipe cell elongation
  publication-title: Fungal Genet. Biol.
  doi: 10.1016/j.fgb.2013.08.007
– volume: 200
  start-page: 487
  year: 2018
  ident: ref_229
  article-title: Polysaccharide isolated from Phellinus linteus mycelia exerts anti-inflammatory effects via MAPK and PPAR signaling pathways
  publication-title: Carbohydr. Polym.
  doi: 10.1016/j.carbpol.2018.08.021
– ident: ref_45
  doi: 10.3389/fmicb.2023.1139679
– volume: 39
  start-page: 6149
  year: 2012
  ident: ref_204
  article-title: Molecular cloning, characterization, and function analysis of a mevalonate pyrophosphate decarboxylase gene from Ganoderma lucidum
  publication-title: Mol. Biol. Rep.
  doi: 10.1007/s11033-011-1431-9
– volume: 24
  start-page: 1
  year: 2022
  ident: ref_219
  article-title: Cordycepin as a Metabolite with Pharmacological Potential: A Review
  publication-title: Int. J. Med. Mushrooms
  doi: 10.1615/IntJMedMushrooms.2022044442
– volume: 38
  start-page: 399
  year: 2015
  ident: ref_238
  article-title: Increased polysaccharide production and biosynthetic gene expressions in a submerged culture of Ganoderma lucidum by the overexpression of the homologous α-phosphoglucomutase gene
  publication-title: Bioproc. Biosyst. Eng.
  doi: 10.1007/s00449-014-1279-1
– volume: 869
  start-page: 161807
  year: 2023
  ident: ref_13
  article-title: Increasing the value of Phragmites australis straw in a sustainable integrated agriculture model (SIAM) comprising edible mushroom cultivation and spent mushroom substrate compost
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2023.161807
– volume: 25
  start-page: 17
  year: 2018
  ident: ref_141
  article-title: Identification and Expression Analysis of Two Oligopeptide Transporter Encoding Genes fvoptl and fvopt2 from Flammulina velutipes
  publication-title: Acta Edulis Fungi
– ident: ref_94
  doi: 10.1093/femsle/fnad015
– volume: 203
  start-page: 5373
  year: 2021
  ident: ref_138
  article-title: The Fvclp1 gene regulates mycelial growth and fruiting body development in edible mushroom Flammulina velutipes
  publication-title: Arch. Microbiol.
  doi: 10.1007/s00203-021-02514-0
– ident: ref_30
  doi: 10.3389/fmicb.2021.815954
– ident: ref_93
  doi: 10.3390/jof8101000
– ident: ref_50
  doi: 10.3390/jof8040401
– volume: 42
  start-page: 520
  year: 2023
  ident: ref_122
  article-title: Characteristics related to sexual reproduction and mating type locus of Inonotus obliquus
  publication-title: Mycosystema
– volume: 17
  start-page: 2419
  year: 2010
  ident: ref_232
  article-title: Lentinus edodes: A macrofungus with pharmacological activities
  publication-title: Curr. Med. Chem.
  doi: 10.2174/092986710791698495
– volume: 39
  start-page: 993
  year: 2020
  ident: ref_146
  article-title: Cytochrome c peroxidase gene (ffccp) and its differential expression during stipe elongation in Flammulina filiformis
  publication-title: Mycosystema
– volume: 165
  start-page: 1593
  year: 2020
  ident: ref_167
  article-title: The role of Rho1 gene in the cell wall integrity and polysaccharides biosynthesis of the edible mushroom Grifola frondosa
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2020.09.239
– ident: ref_242
  doi: 10.3390/foods10010095
– ident: ref_17
  doi: 10.3390/jof8060581
– volume: 123
  start-page: 200
  year: 2019
  ident: ref_62
  article-title: Identification and expression analysis of Pofst3 suggests a role during Pleurotus ostreatus primordia formation
  publication-title: Fungal Biol.
  doi: 10.1016/j.funbio.2018.12.008
– volume: 7
  start-page: 1260
  year: 2017
  ident: ref_84
  article-title: Genome editing in the mushroom-forming basidiomycete Coprinopsis cinerea, optimized by a high-throughput transformation system
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-017-00883-5
– volume: 105
  start-page: 7353
  year: 2021
  ident: ref_209
  article-title: The non-canonical functions of telomerase reverse transcriptase gene GlTert on regulating fungal growth, oxidative stress, and ganoderic acid biosynthesis in Ganoderma lucidum
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-021-11564-9
– ident: ref_26
  doi: 10.1016/j.mtbio.2023.100560
– volume: 18
  start-page: 115
  year: 2019
  ident: ref_203
  article-title: Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum
  publication-title: Microb. Cell Fact.
  doi: 10.1186/s12934-019-1164-3
– volume: 60
  start-page: 351
  year: 2019
  ident: ref_67
  article-title: Differential expression of two gpd genes in the cultivated mushroom Pleurotus eryngii using RNA sequencing analysis
  publication-title: Mycoscience
  doi: 10.1016/j.myc.2019.06.004
– volume: 179
  start-page: 54
  year: 2015
  ident: ref_155
  article-title: Cloning and functional analysis of a laccase gene during fruiting body formation in Hypsizygus marmoreus
  publication-title: Microbiol. Res.
  doi: 10.1016/j.micres.2015.06.005
– volume: 243
  start-page: 307
  year: 2019
  ident: ref_40
  article-title: The efficient genetic transformation of Cordyceps militaris by using mononuclear protoplasts
  publication-title: Sci. Hortic.
  doi: 10.1016/j.scienta.2018.08.043
– volume: 49
  start-page: 801
  year: 2022
  ident: ref_20
  article-title: Studies on Transcriptome During Fruiting Body Development of Lentinula edodes
  publication-title: Acta Hortic. Sin.
– volume: 37
  start-page: 1628
  year: 2018
  ident: ref_161
  article-title: Expression analyses of Vvrin1 gene encoding MADS-box transcription factors in different development stages of Volvariella volvacea
  publication-title: Mycosystema
– ident: ref_207
  doi: 10.1128/AEM.00156-21
– volume: 9
  start-page: 847
  year: 2010
  ident: ref_118
  article-title: Basidiomycete mating type genes and pheromone signaling
  publication-title: Eukaryot. Cell
  doi: 10.1128/EC.00319-09
– volume: 36
  start-page: 1293
  year: 2020
  ident: ref_220
  article-title: Advances in biosynthesis of cordycepin from Cordyceps militaris
  publication-title: Chin. J. Biotechnol.
– ident: ref_129
  doi: 10.1093/femsle/fnad036
– ident: ref_240
  doi: 10.1016/j.ijbiomac.2023.126778
– ident: ref_65
  doi: 10.1007/s11274-018-2529-1
– volume: 163
  start-page: 1466
  year: 2017
  ident: ref_206
  article-title: Alternative oxidase impacts ganoderic acid biosynthesis by regulating intracellular ROS levels in Ganoderma lucidum
  publication-title: Microbiology
  doi: 10.1099/mic.0.000527
– volume: 78
  start-page: 7968
  year: 2012
  ident: ref_60
  article-title: Enhancement of ganoderic acid accumulation by overexpression of an N-terminally truncated 3-hydroxy-3-methylglutaryl coenzyme A reductase gene in the basidiomycete Ganoderma lucidum
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.01263-12
– volume: 67
  start-page: 8875
  year: 2019
  ident: ref_235
  article-title: Functions of a Glucan Synthase Gene GFGLS in Mycelial Growth and Polysaccharide Production of Grifola frondosa
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.9b03569
– volume: 24
  start-page: 307
  year: 2019
  ident: ref_248
  article-title: Fungal immunomodulatory proteins: Characteristic, potential antitumor activities and their molecular mechanisms
  publication-title: Drug Discov. Today
  doi: 10.1016/j.drudis.2018.09.014
– volume: 56
  start-page: 111
  year: 2019
  ident: ref_99
  article-title: In vivo production of psilocybin in E. coli
  publication-title: Metab. Eng.
  doi: 10.1016/j.ymben.2019.09.009
– volume: 9
  start-page: e16682
  year: 2023
  ident: ref_192
  article-title: Triterpenoids of Ganoderma lucidum inhibited S180 sarcoma and H22 hepatoma in mice by regulating gut microbiota
  publication-title: Heliyon
  doi: 10.1016/j.heliyon.2023.e16682
– volume: 115
  start-page: 360
  year: 2013
  ident: ref_49
  article-title: Characterization of a gene coding for a putative adenosine deaminase-related growth factor by RNA interference in the Basidiomycete Flammulina velutipes
  publication-title: J. Biosci. Bioeng.
  doi: 10.1016/j.jbiosc.2012.10.020
– volume: 37
  start-page: 576
  year: 2018
  ident: ref_55
  article-title: Functional analyses of anthranilate synthase gene LetrpE in Lentinula edodes by RNAi mediated gene knockdown
  publication-title: Mycosystema
– ident: ref_22
  doi: 10.3390/molecules26216708
– volume: 125
  start-page: 38
  year: 2019
  ident: ref_231
  article-title: Acetylation of polysaccharide from Morchella angusticeps peck enhances its immune activation and anti-inflammatory activities in macrophage RAW264.7 cells
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2018.12.036
– volume: 41
  start-page: 480
  year: 2023
  ident: ref_12
  article-title: Harnessing synthetic biology for mushroom farming
  publication-title: Trends Biotechnol.
  doi: 10.1016/j.tibtech.2022.10.001
– ident: ref_173
  doi: 10.1016/j.biortech.2022.126792
– ident: ref_116
  doi: 10.2307/1293845
– volume: 105
  start-page: 2815
  year: 2021
  ident: ref_154
  article-title: Genetic and functional analysis of the Zn(II)(2)Cys(6) transcription factor HADA-1 in Hypsizygus marmoreus
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-021-11175-4
– volume: 39
  start-page: 1049
  year: 2020
  ident: ref_160
  article-title: Construction of the overexpression transformant strains with MADS-box transcription factor Vvrin1 gene and analysis on differential growth rate of Volvariella volvacea
  publication-title: Mycosystema
– volume: 2019
  start-page: 3139689
  year: 2019
  ident: ref_257
  article-title: Protective Function of Novel Fungal Immunomodulatory Proteins Fip-lti1 and Fip-lti2 from Lentinus tigrinus in Concanavalin A-Induced Liver Oxidative Injury
  publication-title: Oxid. Med. Cell. Longev.
  doi: 10.1155/2019/3139689
– volume: 166
  start-page: 949
  year: 1950
  ident: ref_215
  article-title: Cordycepin, a metabolic product isolated from cultures of Cordyceps militaris (Linn.) Link
  publication-title: Nature
  doi: 10.1038/166949a0
– volume: 13
  start-page: 1034545
  year: 2022
  ident: ref_246
  article-title: Immune regulatory functions of biologically active proteins from edible fungi
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2022.1034545
– volume: 24
  start-page: 1479
  year: 2017
  ident: ref_223
  article-title: Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin
  publication-title: Cell Chem. Biol.
  doi: 10.1016/j.chembiol.2017.09.001
– volume: 103
  start-page: 7835
  year: 2019
  ident: ref_63
  article-title: Advances in research on Cordyceps militaris degeneration
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-019-10074-z
– ident: ref_243
  doi: 10.3390/ijms24054864
– volume: 62
  start-page: 55
  year: 1998
  ident: ref_119
  article-title: Molecular genetics of mating recognition in basidiomycete fungi
  publication-title: Microbiol. Mol. Biol. R.
  doi: 10.1128/MMBR.62.1.55-70.1998
– volume: 39
  start-page: 1056
  year: 2020
  ident: ref_181
  article-title: Bioinformatics analysis of manganese peroxidase gene (LeMnP1) in Lentinula edodes and effects of high temperature stress on its expression
  publication-title: Mycosystema
– ident: ref_241
  doi: 10.3389/fbioe.2021.796278
– ident: ref_2
– ident: ref_230
  doi: 10.1016/j.bcab.2021.102163
– volume: 309
  start-page: 111623
  year: 2023
  ident: ref_185
  article-title: Blue light and its receptor white collar complex (FfWCC) regulates mycelial growth and fruiting body development in Flammulina filiformis
  publication-title: Sci. Hortic.
  doi: 10.1016/j.scienta.2022.111623
– volume: 85
  start-page: e01735-01719
  year: 2019
  ident: ref_139
  article-title: A Single Transcription Factor (PDD1) Determines Development and Yield of Winter Mushroom (Flammulina velutipes)
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.01735-19
– volume: 116
  start-page: 109759
  year: 2023
  ident: ref_218
  article-title: Cordycepin suppresses vascular inflammation, apoptosis and oxidative stress of arterial smooth muscle cell in thoracic aortic aneurysm with VEGF inhibition
  publication-title: Int. Immunopharmacol.
  doi: 10.1016/j.intimp.2023.109759
– volume: 217
  start-page: 132
  year: 2016
  ident: ref_239
  article-title: Improved polysaccharide production in a submerged culture of Ganoderma lucidum by the heterologous expression of Vitreoscilla hemoglobin gene
  publication-title: J. Biotechnol.
  doi: 10.1016/j.jbiotec.2015.11.011
– volume: 42
  start-page: 131
  year: 2023
  ident: ref_46
  article-title: Native bio-function of FIP-fve towards Flammulina filiformis
  publication-title: J. Huazhong Agric. Univ.
– volume: 168
  start-page: 527
  year: 2013
  ident: ref_250
  article-title: Functional expression of FIP-fve, a fungal immunomodulatory protein from the edible mushroom Flammulina velutipes in Pichia pastoris GS115
  publication-title: J. Biotechnol.
  doi: 10.1016/j.jbiotec.2013.09.013
– volume: 150
  start-page: 536
  year: 2020
  ident: ref_103
  article-title: Heterologous expression and characterization of a novel chitin deacetylase, CDA3, from the mushroom Coprinopsis cinerea
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2020.02.083
– volume: 47
  start-page: 698
  year: 2018
  ident: ref_143
  article-title: fv-gs6: A glucan synthase gene associated with stipe elongation of Flammulina velutipes
  publication-title: J. Fujian Agric. For. Univ. (Nat. Sci. Ed.)
– volume: 8
  start-page: 242
  year: 2023
  ident: ref_222
  article-title: Engineering Komagataella phaffii to biosynthesize cordycepin from methanol which drives global metabolic alterations at the transcription level
  publication-title: Synth. Syst. Biotechnol.
  doi: 10.1016/j.synbio.2023.03.003
– volume: 17
  start-page: 224
  year: 2019
  ident: ref_36
  article-title: Research on Edible Fungi Genetic System
  publication-title: J. Fungal Res.
– volume: 48
  start-page: 4054
  year: 2021
  ident: ref_179
  article-title: Expression of catalase gene (VvCAT1) from Volvariella volvacea in Escherichia coli and its temperature tolerance
  publication-title: Microbiol. China
– volume: 14
  start-page: 2343
  year: 2021
  ident: ref_91
  article-title: Efficient genome editing in filamentous fungi via an improved CRISPR-Cas9 ribonucleoprotein method facilitated by chemical reagents
  publication-title: Microb. Biotechnol.
  doi: 10.1111/1751-7915.13652
– volume: 42
  start-page: 344
  year: 2023
  ident: ref_113
  article-title: Induction of sexual fruiting-body formation by pairing the opposite mating-type isolates of Cordyceps militaris
  publication-title: Mycosystema
– volume: 152
  start-page: 7
  year: 2018
  ident: ref_76
  article-title: Efficient transformation of Pleurotus eryngii with a safe selective marker mutated from the Pesdi1 gene
  publication-title: J. Microbiol. Methods
  doi: 10.1016/j.mimet.2018.07.006
– ident: ref_28
  doi: 10.1016/j.fbio.2023.102486
– volume: 18
  start-page: 4687
  year: 2016
  ident: ref_175
  article-title: Functional analysis of Agaricus bisporus serine proteinase 1 reveals roles in utilization of humic rich substrates and adaptation to the leaf-litter ecological niche
  publication-title: Environ. Microbiol.
  doi: 10.1111/1462-2920.13350
– volume: 40
  start-page: 2065
  year: 2021
  ident: ref_66
  article-title: Expression analyses of exogenous genes controlled by different promoters in Hypsizygus marmoreus
  publication-title: Mycosystema
– volume: 30
  start-page: 9
  year: 2023
  ident: ref_83
  article-title: Construction of a CRISPR/Cas9-Based Genome Editing System in Ganoderma lucidum “Hunong No.1’Cultivar
  publication-title: Acta Edulis Fungi
– volume: 2
  start-page: e00446-00417
  year: 2017
  ident: ref_89
  article-title: A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates
  publication-title: mSphere
– volume: 26
  start-page: 119
  year: 2019
  ident: ref_95
  article-title: Application of CRISPR/Cas9 Technology in Macrofungi Research
  publication-title: Acta Edulis Fungi
– volume: 82
  start-page: 4112
  year: 2016
  ident: ref_210
  article-title: Heat Stress Modulates Mycelium Growth, Heat Shock Protein Expression, Ganoderic Acid Biosynthesis, and Hyphal Branching of Ganoderma lucidum via Cytosolic Ca2
  publication-title: Appl. Environ. Microb.
  doi: 10.1128/AEM.01036-16
– ident: ref_33
  doi: 10.1128/mbio.03626-21
– volume: 147
  start-page: 110452
  year: 2021
  ident: ref_234
  article-title: Homologous overexpression of genes in Cordyceps militaris improves the production of polysaccharides
  publication-title: Food Res. Int.
  doi: 10.1016/j.foodres.2021.110452
– ident: ref_10
– volume: 52
  start-page: 850
  year: 2012
  ident: ref_106
  article-title: Overexpression and characterization of a laccase gene from Pleurotus ostreatus in Trichoderma reesei
  publication-title: Acta Microbiol. Sin.
– ident: ref_176
  doi: 10.3389/fmicb.2021.724451
– volume: 56
  start-page: 177
  year: 2015
  ident: ref_186
  article-title: A putative transcription factor Gf.BMR1 in Grifola frondosa, the homolog of BMR1 in Bipolaris oryzae, was strongly induced by near-ultraviolet light and blue light
  publication-title: Mycoscience
  doi: 10.1016/j.myc.2014.05.005
– volume: 33
  start-page: 1268
  year: 2014
  ident: ref_44
  article-title: Agrobacterium-mediated Transformation of an Endogenous HMG-box Transcription Factor fvhom1 in Flammulina velutipes
  publication-title: Genom. Appl. Biol.
– volume: 104
  start-page: 6855
  year: 2020
  ident: ref_249
  article-title: Anticancer potentiality and mode of action of low-carbohydrate proteins and peptides from mushrooms
  publication-title: Appl. Microbiol. Biot.
  doi: 10.1007/s00253-020-10707-8
– volume: 29
  start-page: 23
  year: 2022
  ident: ref_123
  article-title: Genetic Structure and Polymorphism of Mating Type Loci in Different Hypsizygus marmoreus Strains
  publication-title: Acta Edulis Fungi
– volume: 43
  start-page: 25
  year: 2017
  ident: ref_78
  article-title: Research progress in transformation of fungi mediated by protoplasts
  publication-title: Plant Prot.
– volume: 106
  start-page: 523
  year: 2022
  ident: ref_213
  article-title: Biosynthesis of a novel ganoderic acid by expressing CYP genes from Ganoderma lucidum in Saccharomyces cerevisiae
  publication-title: Appl. Microbiol. Biot.
  doi: 10.1007/s00253-021-11717-w
– ident: ref_71
  doi: 10.3390/genes10060467
– volume: 184
  start-page: 112677
  year: 2021
  ident: ref_74
  article-title: Enhancement of antroquinonol production via the overexpression of 4-hydroxybenzoate polyprenyltransferase biosynthesis-related genes in Antrodia cinnamomea
  publication-title: Phytochemistry
  doi: 10.1016/j.phytochem.2021.112677
– volume: 13
  start-page: 7740
  year: 2022
  ident: ref_109
  article-title: Biosynthesis of mushroom-derived type II ganoderic acids by engineered yeast
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-022-35500-1
– volume: 92
  start-page: 94
  year: 2019
  ident: ref_3
  article-title: Trends of utilizing mushroom polysaccharides (MPs) as potent nutraceutical components in food and medicine: A comprehensive review
  publication-title: Trends Food Sci. Technol.
  doi: 10.1016/j.tifs.2019.08.009
– volume: 132
  start-page: 162
  year: 2023
  ident: ref_221
  article-title: Microbial synthesis of cordycepin, current systems and future perspectives
  publication-title: Trends Food Sci. Technol.
  doi: 10.1016/j.tifs.2023.01.006
– volume: 43
  start-page: 327
  year: 2015
  ident: ref_144
  article-title: Cloning and Expression Analysis of Phenylalanine Ammonia-Lyase Gene in the Mycelium and Fruit Body of the Edible Mushroom Flammulina velutipes
  publication-title: Mycobiology
  doi: 10.5941/MYCO.2015.43.3.327
– ident: ref_19
  doi: 10.3390/genes13061080
– ident: ref_169
  doi: 10.3389/fmicb.2018.02944
– volume: 15
  start-page: 2982
  year: 2022
  ident: ref_110
  article-title: Multiplex gene precise editing and large DNA fragment deletion by the CRISPR-Cas9-TRAMA system in edible mushroom Cordyceps militaris
  publication-title: Microb. Biotechnol.
  doi: 10.1111/1751-7915.14147
– volume: 107
  start-page: 6179
  year: 2023
  ident: ref_168
  article-title: Transcription factors: Switches for regulating growth and development in macrofungi
  publication-title: Appl. Microbiol. Biot.
  doi: 10.1007/s00253-023-12726-7
– ident: ref_196
  doi: 10.3390/nu14112268
– volume: 39
  start-page: 1152
  year: 2020
  ident: ref_124
  article-title: Analyses of mating systems in Stropharia rugosoannulata based on genomic data
  publication-title: Mycosystema
– volume: 10
  start-page: 408
  year: 2021
  ident: ref_6
  article-title: Healthy function and high valued utilization of edible fungi
  publication-title: Food Sci. Hum. Well
  doi: 10.1016/j.fshw.2021.04.003
– ident: ref_27
  doi: 10.3390/ijms20246116
– volume: 223
  start-page: 1320
  year: 2022
  ident: ref_24
  article-title: Comparative proteomic analysis reveals differential protein expression of Hypsizygus marmoreus in response to different light qualities
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2022.11.037
– volume: 7
  start-page: 664
  year: 2022
  ident: ref_92
  article-title: Efficient genome editing in Claviceps purpurea using a CRISPR/Cas9 ribonucleoprotein method
  publication-title: Synth. Syst. Biotechnol.
  doi: 10.1016/j.synbio.2022.02.002
– volume: 213
  start-page: 113791
  year: 2023
  ident: ref_194
  article-title: Lanostane triterpenoids with anti-proliferative and anti-inflammatory activities from medicinal mushroom Ganoderma lingzhi
  publication-title: Phytochemistry
  doi: 10.1016/j.phytochem.2023.113791
– volume: 294
  start-page: 663
  year: 2019
  ident: ref_72
  article-title: Exploring molecular tools for transformation and gene expression in the cultivated edible mushroom Agrocybe aegerita
  publication-title: Mol. Genet. Genom.
  doi: 10.1007/s00438-018-01528-6
– ident: ref_70
  doi: 10.1007/s11274-017-2378-3
– volume: 103
  start-page: 7843
  year: 2019
  ident: ref_73
  article-title: Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-019-10016-9
– volume: 56
  start-page: 2103
  year: 2016
  ident: ref_254
  article-title: Discovery and Characterization of the Highly Active Fungal Immunomodulatory Protein Fip-vvo82
  publication-title: J. Chem. Inf. Model.
  doi: 10.1021/acs.jcim.6b00087
– ident: ref_174
  doi: 10.1016/j.biortech.2020.124119
– ident: ref_38
  doi: 10.1016/j.mimet.2020.105878
– volume: 62
  start-page: 106
  year: 2021
  ident: ref_128
  article-title: Identification, characterization and expression of A-mating type genes in monokaryons and dikaryons of the edible mushroom Mycoleptodonoides aitchisonii (Bunaharitake)
  publication-title: Mycoscience
  doi: 10.47371/mycosci.2020.11.008
– volume: 35
  start-page: 292
  year: 2010
  ident: ref_1
  article-title: The nutritional and health benefits of mushrooms
  publication-title: Nutr. Bull.
  doi: 10.1111/j.1467-3010.2010.01859.x
– volume: 20
  start-page: 1982
  year: 2021
  ident: ref_9
  article-title: Reviewing the world’s edible mushroom species: A new evidence-based classification system
  publication-title: Compr. Rev. Food Sci. Food Saf.
  doi: 10.1111/1541-4337.12708
– ident: ref_258
  doi: 10.3390/molecules28124796
– ident: ref_247
  doi: 10.1016/j.ijbiomac.2023.124648
– volume: 5
  start-page: 277
  year: 2022
  ident: ref_214
  article-title: Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi
  publication-title: Nat. Catal.
  doi: 10.1038/s41929-022-00762-x
– volume: 22
  start-page: 107
  year: 2020
  ident: ref_208
  article-title: In Ganoderma lucidum, Glsnf1 regulates cellulose degradation by inhibiting GlCreA during the utilization of cellulose
  publication-title: Environ. Microbiol.
  doi: 10.1111/1462-2920.14826
– volume: 106
  start-page: 4907
  year: 2022
  ident: ref_259
  article-title: Genome-scale metabolic network models: From first-generation to next-generation
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-022-12066-y
– volume: 152
  start-page: 148
  year: 2018
  ident: ref_68
  article-title: A colonized millet grain method for Agrobacterium-mediated transformation of the button mushroom Agaricus bisporus
  publication-title: J. Microbiol. Method
  doi: 10.1016/j.mimet.2018.07.018
– volume: 48
  start-page: 212
  year: 1949
  ident: ref_115
  article-title: Multiple-Allelomorph Heterothallism in the Fungi
  publication-title: New Phytol.
  doi: 10.1111/j.1469-8137.1949.tb05120.x
– ident: ref_172
  doi: 10.1016/j.biortech.2023.128888
– ident: ref_142
  doi: 10.3389/fmicb.2020.00498
– volume: 161
  start-page: 1161
  year: 2020
  ident: ref_237
  article-title: UDP-glucose pyrophosphorylase gene affects mycelia growth and polysaccharide synthesis of Grifola frondosa
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2020.06.139
– ident: ref_25
  doi: 10.1016/j.postharvbio.2021.111786
– volume: 102
  start-page: 5483
  year: 2018
  ident: ref_253
  article-title: Molecular cloning, codon-optimized gene expression, and bioactivity assessment of two novel fungal immunomodulatory proteins from Ganoderma applanatum in Pichia
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-018-9022-5
– volume: 49
  start-page: 2563
  year: 2022
  ident: ref_145
  article-title: Differential expression of key genes in pheromone signaling pathway in fruiting body development of Flammulina filiformis
  publication-title: Microbiol. China
– ident: ref_112
  doi: 10.1002/cbic.202300008
– ident: ref_126
  doi: 10.3390/jof9100959
– ident: ref_86
  doi: 10.3389/fmicb.2018.01157
– ident: ref_158
  doi: 10.1007/s11274-019-2741-7
– volume: 36
  start-page: 1111
  year: 2017
  ident: ref_130
  article-title: Cloning and function analysis of fruiting body lectin gene from Pleurotus ostreatus
  publication-title: Mycosystema
– volume: 168
  start-page: 110254
  year: 2023
  ident: ref_105
  article-title: Heterologous expression, purification, and characterization of a recombinant Cordyceps militaris lipase from Candida rugosa-like family in Pichia pastoris
  publication-title: Enzyme Microb. Technol.
  doi: 10.1016/j.enzmictec.2023.110254
– volume: 35
  start-page: 946
  year: 2016
  ident: ref_159
  article-title: Cloning and functional prediction of the Ppcsl-1 related to change-temperature fruiting of Pleurotus pulmonarius
  publication-title: Mycosystema
– volume: 198
  start-page: 113131
  year: 2022
  ident: ref_195
  article-title: Lanostane-type triterpenoids from the mycelial mat of Ganoderma lucidum and their hepatoprotective activities
  publication-title: Phytochemistry
  doi: 10.1016/j.phytochem.2022.113131
– volume: 61
  start-page: 2397
  year: 2021
  ident: ref_251
  article-title: Overexpression and activity analysis of Antrodia camphorata immunomodulatory protein
  publication-title: Acta Microbiol. Sin.
– volume: 1
  start-page: 53
  year: 2013
  ident: ref_244
  article-title: Schizophyllan: A review on its structure, properties, bioactivities and recent developments
  publication-title: Bioact. Carbohydr. Diet. Fibre
  doi: 10.1016/j.bcdf.2013.01.002
– volume: 9
  start-page: 7632
  year: 2019
  ident: ref_90
  article-title: High-throughput targeted gene deletion in the model mushroom Schizophyllum commune using pre-assembled Cas9 ribonucleoproteins
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-44133-2
– ident: ref_7
  doi: 10.1016/j.ijbiomac.2023.124291
– volume: 22
  start-page: 20
  year: 2023
  ident: ref_97
  article-title: Microbial cell factories based on filamentous bacteria, yeasts, and fungi
  publication-title: Microb. Cell Fact.
  doi: 10.1186/s12934-023-02025-1
– volume: 22
  start-page: 15
  year: 2015
  ident: ref_131
  article-title: Cloning and Expression of a fst3 Gene from Pleurotus ostreatus
  publication-title: Acta Edulis Fungi
– ident: ref_200
  doi: 10.3389/fmicb.2022.878110
– volume: 104
  start-page: 1661
  year: 2020
  ident: ref_79
  article-title: CRISPR-Cas9 assisted functional gene editing in the mushroom Ganoderma lucidum
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-019-10298-z
– volume: 106
  start-page: 563
  year: 2022
  ident: ref_236
  article-title: The β-1,3-glucan synthase gene GFGLS2 plays major roles in mycelial growth and polysaccharide synthesis in Grifola frondosa
  publication-title: Appl. Microbiol. Biot.
  doi: 10.1007/s00253-021-11734-9
– volume: 15
  start-page: 2594
  year: 2022
  ident: ref_87
  article-title: Efficient CRISPR/Cas9 system based on autonomously replicating plasmid with an AMA1 sequence and precisely targeted gene deletion in the edible fungus, Cordyceps militaris
  publication-title: Microb. Biotechnol.
  doi: 10.1111/1751-7915.14107
– volume: 22
  start-page: 107
  year: 2022
  ident: ref_104
  article-title: Cloning of the Transglutaminase Gene from Cordyceps militaris and Its Expressionin Pichia pastoris
  publication-title: J. Chin. Inst. Food Sci. Technol.
– ident: ref_224
  doi: 10.3389/fmicb.2020.01038
– volume: 2014
  start-page: 805841
  year: 2014
  ident: ref_191
  article-title: Mushrooms: A potential natural source of anti-inflammatory compounds for medical applications
  publication-title: Mediat. Inflamm.
  doi: 10.1155/2014/805841
– volume: 107
  start-page: 108695
  year: 2022
  ident: ref_216
  article-title: Cordycepin enhances anti-tumor immunity in colon cancer by inhibiting phagocytosis immune checkpoint CD47 expression
  publication-title: Int. Immunopharmacol.
  doi: 10.1016/j.intimp.2022.108695
– volume: 13
  start-page: 386
  year: 2020
  ident: ref_82
  article-title: Dual sgRNA-directed gene deletion in basidiomycete Ganoderma lucidum using the CRISPR/Cas9 system
  publication-title: Microb. Biotechnol.
  doi: 10.1111/1751-7915.13534
– ident: ref_165
  doi: 10.3390/jof9040412
– ident: ref_151
  doi: 10.3390/ijms24054586
– volume: 56
  start-page: 1036
  year: 2016
  ident: ref_166
  article-title: Expression of α-glucosidase during morphological differentiation in the basidiomycetous fungus Pholiota microspora
  publication-title: J. Basic. Microb.
  doi: 10.1002/jobm.201500752
– volume: 2234
  start-page: 87
  year: 2021
  ident: ref_107
  article-title: CRISPR/Cas9-Mediated Genome Editing of Trichoderma reesei
  publication-title: Methods Mol. Biol.
  doi: 10.1007/978-1-0716-1048-0_8
– ident: ref_41
– volume: 46
  start-page: 3233
  year: 2019
  ident: ref_100
  article-title: Heterologous expression and characterization of the key enzymes involved in sugar donor synthesis of polysaccharide in Ganoderma lucidum
  publication-title: Microbiol. China
– volume: 15
  start-page: 4491
  year: 2017
  ident: ref_47
  article-title: Construction of Silencing Vector for FIP-fve Gene and Genetic Transformation of Enoki Mushroom (Flammulina velutipes)
  publication-title: Mol. Plant Breed.
– volume: 22
  start-page: 7
  year: 2015
  ident: ref_69
  article-title: Efficiency of Flammulina velutipes Transformation by Agrobacterium tumefaciens-mediated Transformation Using Different Receptors
  publication-title: Acta Edulis Fungi
– volume: 38
  start-page: 331
  year: 2010
  ident: ref_43
  article-title: Highly Efficient Electroporation-mediated Transformation into Edible Mushroom Flammulina velutipes
  publication-title: Mycobiology
  doi: 10.4489/MYCO.2010.38.4.331
– ident: ref_127
  doi: 10.1128/spectrum.05272-22
– ident: ref_35
  doi: 10.3390/jof9060688
– volume: 23
  start-page: 1112
  year: 2015
  ident: ref_42
  article-title: Liposome-mediated Fruit Body Gill Tissue Transformation of Agaricus bisporus and Function Exploration of 1-aminocyclopropane-1-carboxylic Acid Oxidase Gene (ACO)
  publication-title: J. Agric. Biotechnol.
– volume: 39
  start-page: 1130
  year: 2020
  ident: ref_120
  article-title: Characterization of clamps and nuclear phases in the monokaryons with transformed mating genes in Pleurotus eryngii
  publication-title: Mycosystema
– ident: ref_18
  doi: 10.1371/journal.pone.0230680
– volume: 199
  start-page: 341
  year: 2022
  ident: ref_171
  article-title: Characterization of yeast cell surface displayed Lentinula edodes xylanase and its effects on the hydrolysis of wheat
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2021.12.178
– volume: 54
  start-page: 100
  year: 2013
  ident: ref_59
  article-title: The cloning, characterization and functional analysis of a gene encoding an acetyl-CoA acetyltransferase involved in triterpene biosynthesis in Ganoderma lucidum
  publication-title: Mycoscience
  doi: 10.1016/j.myc.2012.09.002
– volume: 100
  start-page: 7151
  year: 2016
  ident: ref_157
  article-title: The transcriptional regulator c2h2 accelerates mushroom formation in Agaricus bisporus
  publication-title: Appl. Microbiol. Biot.
  doi: 10.1007/s00253-016-7574-9
– volume: 39
  start-page: 827
  year: 2020
  ident: ref_189
  article-title: Functions of gene ATX1 under cadmium stress in Morchella importuna
  publication-title: Mycosystema
– volume: 30
  start-page: 1
  year: 2023
  ident: ref_132
  article-title: Analysis of HMG-box Transcription Factors in Pleurotus ostreatus and Cloning of a Candidate Gene
  publication-title: Acta Edulis Fungi
– volume: 352
  start-page: 190
  year: 2014
  ident: ref_182
  article-title: Photo morphogenesis and photo response of the blue-light receptor gene Cmwc-1 in different strains of Cordyceps militaris
  publication-title: FEMS Microbiol. Lett.
  doi: 10.1111/1574-6968.12393
– volume: 25
  start-page: 35
  year: 2018
  ident: ref_205
  article-title: Identification and Analysis of Candidate Cytochrome P450 Genes Involved in the Biosynthesis of Ganoderic Acid in Ganoderma lingzhi
  publication-title: Acta Edulis Fungi
– volume: 58
  start-page: 2100
  year: 2018
  ident: ref_53
  article-title: Function analysis of HMG-box transcription factor lelcrp1 in Lentinula edodes
  publication-title: Acta Microbiol. Sin.
– ident: ref_134
  doi: 10.3390/ijms24098143
– volume: 33
  start-page: 1
  year: 2017
  ident: ref_255
  article-title: Comparative analysis of two fungal immunomodulatory proteins LZ-8 and LZ-9 of Ganoderma lucidum
  publication-title: Acta Agric. Shanghai
– volume: 78
  start-page: 1556
  year: 2015
  ident: ref_61
  article-title: Characterization of the 2,3-Oxidosqualene Cyclase Gene from Antrodia cinnamomea and Enhancement of Cytotoxic Triterpenoid Compound Production
  publication-title: J. Nat. Prod.
  doi: 10.1021/acs.jnatprod.5b00020
– volume: 1
  start-page: 128
  year: 2021
  ident: ref_5
  article-title: Polysaccharides from edible fungi Pleurotus spp.: Advances and perspectives
  publication-title: J. Future Foods
  doi: 10.1016/j.jfutfo.2022.01.002
– volume: 34
  start-page: 107
  year: 2018
  ident: ref_163
  article-title: Sequence Characterization and Differential Expression Analysis of a Aryl Alcohol Oxidase Gene vvaao1 from Volvariella volvacea
  publication-title: Biotechnol. Bull.
– volume: 104
  start-page: 10737
  year: 2020
  ident: ref_211
  article-title: Nitrate reductase-dependent nitric oxide plays a key role on MeJA-induced ganoderic acid biosynthesis in Ganoderma lucidum
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-020-10951-y
– ident: ref_51
  doi: 10.3389/fmicb.2022.1009885
– ident: ref_137
  doi: 10.3390/ijms17121884
– volume: 59
  start-page: 119
  year: 2018
  ident: ref_152
  article-title: Sequence analysis and heterologous expression of lectin-like gene CMLec3 from the medicinal fungus Cordyceps militaris
  publication-title: Mycoscience
  doi: 10.1016/j.myc.2017.09.001
– volume: 108
  start-page: 1104
  year: 2016
  ident: ref_148
  article-title: The pH-responsive transcription factor PacC regulates mycelial growth, fruiting body development, and ganoderic acid biosynthesis in Ganoderma lucidum
  publication-title: Mycologia
– ident: ref_85
– volume: 60
  start-page: 246
  year: 2019
  ident: ref_164
  article-title: Overexpression of the laccase gene, lcc1, in Lentinula edodes using the pChG vector
  publication-title: Mycoscience
  doi: 10.1016/j.myc.2019.02.004
– volume: 112
  start-page: 80
  year: 2022
  ident: ref_101
  article-title: A uridine diphosphate-glycosyltransferase GFUGT88A1 derived from edible mushroom Grifola frondosa extends oligosaccharide chains
  publication-title: Process Biochem.
  doi: 10.1016/j.procbio.2021.11.024
– volume: 60
  start-page: 19
  year: 2017
  ident: ref_198
  article-title: Triterpenoid biosynthesis and the transcriptional response elicited by nitric oxide in submerged fermenting Ganoderma lucidum
  publication-title: Process Biochem.
  doi: 10.1016/j.procbio.2017.05.029
– volume: 28
  start-page: 11
  year: 2021
  ident: ref_56
  article-title: Functional Analysis of Indole-3-pyruvate Monooxygenase Gene YUCCA8 Involved in Heat Resistance of Lentinula edodes by RNAi
  publication-title: Acta Edulis Fungi
– volume: 123
  start-page: 95
  year: 2019
  ident: ref_162
  article-title: Characterization and expression pattern of homeobox transcription factors in fruiting body development of straw mushroom Volvariella volvacea
  publication-title: Fungal. Biol.
  doi: 10.1016/j.funbio.2018.10.008
– volume: 27
  start-page: 51
  year: 2020
  ident: ref_180
  article-title: Heterologous Expression of Manganese Superoxide Dismutase from Volvariella volvacea in E. coli and Characterization of ts Stress Tolerance
  publication-title: Acta Edulis Fungi
– volume: 36
  start-page: 1514
  year: 2017
  ident: ref_64
  article-title: Agrobacterium-mediated transformation of the Lentinula edodes mycelia
  publication-title: Mycosystema
– ident: ref_96
  doi: 10.3389/fmicb.2023.1169884
– volume: 23
  start-page: 1286
  year: 2021
  ident: ref_212
  article-title: Regulation of glutamine synthetase activity by transcriptional and posttranslational modifications negatively influences ganoderic acid biosynthesis in Ganoderma lucidum
  publication-title: Environ. Microbiol.
  doi: 10.1111/1462-2920.15400
– volume: 706
  start-page: 84
  year: 2019
  ident: ref_136
  article-title: A hydrophobin gene, Hyd9, plays an important role in the formation of aerial hyphae and primordia in Flammulina filiformis
  publication-title: Gene
  doi: 10.1016/j.gene.2019.04.067
– volume: 28
  start-page: 1
  year: 2021
  ident: ref_147
  article-title: Subcellular Localization of Ganoderma lucidum CRZl and Transcription Levels of crzl at Different Developmental Stages
  publication-title: Acta Edulis Fungi
– volume: 40
  start-page: 806
  year: 2021
  ident: ref_14
  article-title: Development and prospect of genetics of edible mushrooms in China
  publication-title: Mycosystema
– volume: 37
  start-page: 14
  year: 2021
  ident: ref_125
  article-title: B Mating Locus from Agrocybe aegerita: Structural Analysis
  publication-title: Chin. Agric. Sci. Bull.
– volume: 123
  start-page: 209
  year: 2019
  ident: ref_133
  article-title: Dominant effects of gat1 mutations on the ligninolytic activity of the white-rot fungus Pleurotus ostreatus
  publication-title: Fungal Biol.
  doi: 10.1016/j.funbio.2018.12.007
– volume: 104
  start-page: 5827
  year: 2020
  ident: ref_140
  article-title: A putative transcription factor LFC1 negatively regulates development and yield of winter mushroom
  publication-title: Appl. Microbiol. Biotechnol.
  doi: 10.1007/s00253-020-10642-8
SSID ssj0001586993
Score 2.3499842
SecondaryResourceType review_article
Snippet Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal...
SourceID doaj
proquest
gale
pubmed
crossref
SourceType Open Website
Aggregation Database
Index Database
Enrichment Source
StartPage 311
SubjectTerms active substances
Amino acids
China
Chitinase
Economic development
Food industry
Fungi
gene editing
Genes
genetic transformation
Genomes
Genomics
Germplasm
Heat shock proteins
Light
macrofungi
mating-type genes
Metabolites
Methods
Nutrient transport
Proteomics
Real estate development
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals (ODIN)
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1NSxwxGA5FevAitVo7VUsKQqG4OLOZzYe3tbhIwdKDgreQZJKyRWbEWQ89-dd9MplZdqvQi7dh8maY5P163pnkCSFHfsK8yaty5GAQo5IZizgYULUaYYpcWaCE-L3j8ie_uC5_3ExuVo76imvCEj1wmriTiRsXYVIazpwtfW6RzlXhy4CyQno2djH6IuetFFNpf7DkyLxpQx5DXX_ypwlFR35SFGspqGPqfx6P_0GZXbaZvSNbPUyk0_R62-SNr9-Tt2cNoNzfHfLYsyrRafqD39J5TYHk6AxZKn3co5FPuqVNoOfV3N56auqKXqYf6WiF4O_5KR3W3dGrgcq1PV59yEBZctx1_3XfdBsz211yPTu_-n4x6k9SgAqkWIz82AYJXy6r4EVQJXeAAcp6hDsrOfKkyI2pPPwdzV4JXBqUUqGSlkHUsQ9ko25q_5FQqDw3kgduIx96HpRlcGvLvJAm5E5l5Nswudr1NOPxtItbjXIjakKvaCIjR0vhu8Su8bLYWdTSUiRSYnc3YCi6NxT9P0PJyNeoYx0dFy_kTL__AMOKFFh6KhSCv2BcZuRgTRIO59abByvRvcO3GmFToaZHdMzIl2Vz7BkXsdW-eYgyPGcCGBMD2kvWtRwSHi1RSfJPrzHUfbI5BvZK6zIPyMbi_sEfAjst7OfOTZ4AFx4Vxg
  priority: 102
  providerName: Directory of Open Access Journals
Title Current Advances in the Functional Genes of Edible and Medicinal Fungi: Research Techniques, Functional Analysis, and Prospects
URI https://www.ncbi.nlm.nih.gov/pubmed/38786666
https://www.proquest.com/docview/3059523225
https://www.proquest.com/docview/3060372561
https://doaj.org/article/5c21f54a63cb4e0b92991e4f4488e32c
Volume 10
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3Pa9swFBZbssMuY7_nrQsaFAajpnZky3IvJd4SyqCljBZ6M5IslYxid3F62Kn_ej_ZctpsY7cQPZso79f3nqRPhOyalBkZVUmoYRBhwqRCHLSoWmUm4yhXQAmu33F8wo_Ok-8X6YVvuLV-W-UQE7tAXTXa9cj3YZc5iiaY3-H1r9DdGuVWV_0VGo_JGCFYiBEZF_OT0x_3XZZUcGTg_mAeQ32__7OxcUeCEsdbqahj7P87Lv-BNruss3hOnnm4SGe9fl-QR6Z-SZ4UDSDd71fk1rMr0Vm_kt_SZU2B6OgC2apv8lHHK93SxtJ5tVRXhsq6osf9gjpGIXi5PKDD_jt6NlC6tnsPXzJQl-x1j5-umu6AZvuanC_mZ1-PQn-jAlQhsnVopsoK-HRSWZPZPOEacCBXBmFPCY58mUVSVgZ-j2GTZ_goUVLZSigGUc3ekFHd1OYdoVB9JAW3XDle9MjmisG9FTOZkDbSeUC-DH9uqT3duLv14qpE2eE0UT7QREB2N8LXPcvGv8UKp6WNiKPG7r5oVpel97Qy1dPYponkTKvERAr4L49NYlGHCsOmOiCfnY5L58D4QVr6cwiYlqPCKmdZjiSQMS4CsrMlCcfT28ODlZTe8dvy3kwD8mkz7J50m9lq09w4GR6xDFgTE3rbW9dmSni1QEXJ3___5R_I0ynQVb_zcoeM1qsb8xHoaK0mZDwrvhWLiXeFSddluAN7ABFH
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwED-NDgleEN8EBhhpCAktWhInjoOEUAutOrZWE-qkvRnbsaeiKRlNJ7Qn_iP-Rs756FZAvO0tii9WnPvdl3O-A9g2CTUyyGNfIyD8mEqFetBi1CpTGQaZQi_B7XdMpmx8FH8-To434Fd3FsalVXY6sVbUeandHvku4jLDoAnh9-Hsu--6Rrm_q10LjQYW--biB4Zs1fu9T8jf11E0Gs4-jv22qwC-Dk-XvomU5YjrOLcmtVnMNJrETBkUfcUZ2ow0kDI3iH0cNlmKlxLDCptzRZFUU5z3BmzGlAVRDzYHw-nhl8tdnYQztPjNQUBKs2D3W2nDuuhKGK6ZvrpDwN924A_vtrZyo7twp3VPSb_B0z3YMMV9uDko0YW8eAA_22pOpN9kDlRkXhD0IMkIrWOzqUhcHeuKlJYM87k6NUQWOZk0P_BxFAlP5u9Il-9HZl0J2Wrn6iRdqZSd-vHDRVkfCK0ewtG1fOtH0CvKwjwBglALJGeWKVeHPbCZoqhOFDUplzbQmQdvu48rdFve3HXZOBUY5jhOiCuc8GB7RXzWVPX4N9nAcWlF4kpx1zfKxYloJVskOgptEktGtYpNoNDfzEITW4x7uaGR9uCN47FwCgNfSMv23AMuy5XeEv00Q6OTUsY92FqjREHX68MdSkSraCpxKRYevFoNuydd8lxhynNHwwKaom-LC3rcoGu1JJyaYwTLnv5_8pdwazybHIiDven-M7gdoWfXZH1uQW-5ODfP0TNbqhetOBD4et0S-Bv3I02j
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1ba9RAFD7UrYgv4t2tVUeoCNKwSSabiyCya3dprV0WaaFvcWYyU7aUpG62SJ_8X_46v8ll21XxrW8hczJkcu6TM98h2tJ9roWbBY6CQDgBFxJ20CBrFZHw3EQiSrD7HQeTcPco-HzcP16jX-1ZGFtW2drEylBnhbJ75D3IZYKkCeLXM01ZxHRn_PH8u2M7SNk_rW07jVpE9vXlD6Rv5Ye9HfD6je-PR4efdp2mwwBeLY4WjvaliSHjQWZ0ZJIgVHCPidQwAzIO4T8iV4hMQw8wrJMIlwIphsliyUGqOOa9ReuRzYo6tD4cTaZfr3Z4-nEI718fCuQ8cXunhfEqABbPW3GDVbeAv33CH5Fu5fHG9-leE6qyQS1bD2hN5w_p9rBAOHn5iH42yE5sUFcRlGyWM0STbAxPWW8wMotpXbLCsFE2k2eaiTxjB_XPfIyC8GT2nrW1f-ywhZMtt69P0sKmbFePT-dFdTi0fExHN_Ktn1AnL3L9jBjEzhVxaEJpMdldk0gO0yK5jmJhXJV06V37cVPVQJ3bjhtnKVIey4n0Gie6tLUkPq8RPv5NNrRcWpJYWO7qRjE_SRstT_vK90w_ECFXMtCuROyZeDowyIFjzX3VpbeWx6k1HnghJZozEFiWheFKB1ECBxTxMO7S5gollF6tDrdSkjZGp0yvVKRLr5fD9klbSJfr4sLShC6PEOdiQU9r6VouCVPHyGbDjf9P_oruQPPSL3uT_ed010eQVxeAblJnMb_QLxCkLeTLRhsYfbtpBfwNWsVR2A
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Current+Advances+in+the+Functional+Genes+of+Edible+and+Medicinal+Fungi%3A+Research+Techniques%2C+Functional+Analysis%2C+and+Prospects&rft.jtitle=Journal+of+fungi+%28Basel%29&rft.au=Li%2C+Wenyun&rft.au=Zou%2C+Gen&rft.au=Bao%2C+Dapeng&rft.au=Wu%2C+Yingying&rft.date=2024-05-01&rft.eissn=2309-608X&rft.volume=10&rft.issue=5&rft_id=info:doi/10.3390%2Fjof10050311&rft_id=info%3Apmid%2F38786666&rft.externalDocID=38786666
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2309-608X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2309-608X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2309-608X&client=summon