Nomogram for preoperative prediction of nodal extracapsular extension or positive surgical margins in oropharyngeal squamous cell carcinoma

• Published in: Oral oncology Vol. 83; pp. 73 - 80
• Main Authors: Hararah, Mohammad K., Stokes, William A., Jones, Bernard L., Oweida, Ayman, Ding, Ding, McDermott, Jessica, Goddard, Julie, Karam, Sana D.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2018
• Subjects: Adjuvant; Aged; Alphapapillomavirus - isolation & purification; Carcinoma; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - surgery; Carcinoma, Squamous Cell - virology; Chemoradiotherapy; Decision making; Female; Head and neck cancer; Human papillomavirus (HPV); Humans; Lymph nodes; Lymphatic Metastasis; Male; Margins of Excision; Nomograms; Oropharyngeal cancer; Oropharyngeal Neoplasms - pathology; Oropharyngeal Neoplasms - surgery; Oropharyngeal Neoplasms - virology; Preoperative Period; Radiation therapy; Squamous cell; Surgical margins; Carcinoma; Squamous cell; Decision making; Oropharyngeal cancer; Head and neck cancer; Surgical margins; Adjuvant; Human papillomavirus (HPV); Radiation therapy; Chemoradiotherapy; Lymph nodes

•Largest analysis of surgically treated HPV positive oropharyngeal SCC.•Preoperative factors predict pathologic extracapsular extension or positive surgical margins.•Preoperative clinical factors include N-staging, T-staging, age, and tumor grade.•Nomogram was built and internally validated for HPV...