Taste Preference Synergy Between Glutamate Receptor Agonists and Inosine Monophosphate in Rats

• Published in: Chemical senses Vol. 25; no. 5; pp. 507 - 515
• Main Authors: Delay, E.R., Beaver, A.J., Wagner, K.A., Stapleton, J.R., Harbaugh, J.O., Catron, K.D., Roper, S.D.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford Oxford University Press 01.10.2000; Oxford Publishing Limited (England)
• Subjects: Animals; Behavioral psychophysiology; Biological and medical sciences; Excitatory Amino Acid Agonists - pharmacology; Fundamental and applied biological sciences. Psychology; Inosine monophosphate; Inosine Monophosphate - pharmacology; Male; Neurotransmission and behavior; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate - drug effects; Sodium Glutamate - pharmacology; Taste - physiology; Agonist; Rat; Rodentia; Licking behavior; Glutamate receptor; Synergism; Mixture; Vertebrata; Mammalia; Animal; Gustation; Perception; Taste; Chemical stimulus

Monosodium glutamate (MSG) elicits a taste called umami and interacts synergistically with nucleotide monophosphates such as 5′-inosine monophosphate (IMP) to potentiate this taste intensity. Indeed, the synergistic interaction of nucleotide monophosphates and MSG is a hallmark of umami. We examined...