Increased binding of peripheral benzodiazepine receptor in mild cognitive impairment–dementia converters measured by positron emission tomography with [11C]DAA1106 - Yasuno, Fumihiko; Kosaka, Jun; Ota, Miho; Higuchi, Makoto; Ito, Hiroshi; Fujimura, Yota; Nozaki, Shoko; Takahashi, Sho; Mizukami, Katsuyoshi; Asada, Takashi; Suhara, Tetsuya (Psychiatry research. Neuroimaging, 2012)
Keywords: [11C]DAA1106; Acetamides; Adult and adolescent clinical studies; Aged; Alzheimer Disease - diagnosis; Alzheimer Disease - metabolism; Alzheimer's disease (AD); Biological and medical sciences; Brain - diagnostic imaging; Brain - metabolism; Case-Control Studies; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - metabolism; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Disease Progression; Female; Follow-Up Studies; Geriatrics; Humans; Male; Medical sciences; Microglia; Microglia - diagnostic imaging; Microglia - metabolism; Middle Aged; Mild cognitive impairment (MCI); Neurology; Organic mental disorders. Neuropsychology; Peripheral benzodiazepine receptor (PBR); Phenyl Ethers; Positron emission tomography; Prognosis; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Radioligand Assay; Radiology; Radiopharmaceuticals; Receptors, GABA - metabolism; Alzheimer's disease (AD); [11C]DAA1106; Positron emission tomography; Mild cognitive impairment (MCI); Peripheral benzodiazepine receptor (PBR); Microglia; [ 11C]DAA1106; Radionuclide study; Human; Peripheral benzodiazepine receptor; Nervous system diseases; Cognitive disorder; C]DAA1106; Alzheimer disease; Neuroglia; Cerebral disorder; Central nervous system disease; Degenerative disease; mild cognitive impairment; [; Emission tomography