Uncovering the predictive and immunomodulatory potential of transient receptor potential melastatin family-related CCNE1 in pan-cancer

• Published in: Molecular cancer Vol. 23; no. 1; pp. 258 - 7
• Main Authors: Zhang, Nan, Zhang, Hao, Li, Shuyu, Wu, Wantao, Luo, Peng, Liu, Zaoqu, Chen, Yu, Xia, Zhiwei, Huang, Chenshen, Cheng, Quan
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.11.2024; BioMed Central; BMC
• Subjects: Biomarkers, Tumor; Cancer; Cancer immunotherapy; Care and treatment; CCNE1; Cell Line, Tumor; Correspondence; Cyclin E - genetics; Cyclin E - metabolism; Gene Expression Regulation, Neoplastic; Health aspects; Humans; Immunomodulation - genetics; Immunotherapy; Immunotherapy - methods; Machine learning; Macrophage; Neoplasms - genetics; Neoplasms - immunology; Neoplasms - metabolism; Neoplasms - pathology; Oncogene Proteins - genetics; Oncogene Proteins - metabolism; Oncology, Experimental; Prognosis; TRPM Cation Channels - genetics; TRPM Cation Channels - metabolism; TRPM family; Tumor microenvironment; TRPM family; Tumor microenvironment; Cancer immunotherapy; CCNE1; Macrophage

Millions of new cases of cancer are diagnosed worldwide each year, making it a serious public health concern. Developments in customized therapy and early detection have significantly enhanced treatment for and results from cancer. Therefore, it is important to investigate new molecular biomarkers....