Prokinetics in acute upper GI bleeding: a meta-analysis

• Published in: Gastrointestinal endoscopy Vol. 72; no. 6; pp. 1138 - 1145
• Main Authors: Barkun, Alan N., Bardou, Marc, Martel, Myriam, Gralnek, Ian M., Sung, Joseph J.Y.
• Format: Journal Article
• Language: English
• Published: Maryland heights, MO Mosby, Inc 01.12.2010; Elsevier
• Subjects: Acute Disease; Biological and medical sciences; Blood Transfusion; Digestive system. Abdomen; Duodenal Diseases - diagnosis; Duodenal Diseases - therapy; Endoscopy; Endoscopy, Digestive System; Erythromycin - administration & dosage; Esophageal Diseases - diagnosis; Esophageal Diseases - therapy; Gastroenterology and Hepatology; Gastroenterology. Liver. Pancreas. Abdomen; Gastrointestinal Agents - administration & dosage; Gastrointestinal Hemorrhage - diagnosis; Gastrointestinal Hemorrhage - therapy; Humans; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Metoclopramide - administration & dosage; Other diseases. Semiology; Premedication; Randomized Controlled Trials as Topic; Stomach Diseases - diagnosis; Stomach Diseases - therapy; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; OR; UGIB; CI; WMD; upper GI bleeding; weighted mean difference; confidence interval; odds ratio; Digestive diseases; Intestinal disease; Gastrointestinal bleeding; Acute

Recent data suggest that administration of prokinetics before gastroscopy may be useful in patients with acute upper GI bleeding (UGIB). Published studies are limited in the number of subjects evaluated, and the conclusions are disparate. To assess the evidence of administering prokinetic agents bef...