Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies

• Published in: Journal of translational medicine Vol. 23; no. 1; pp. 130 - 12
• Main Authors: Ye, Gui-Chen, Peng, Hao, Xiang, Jia-Cheng, Miao, Ling-Tao, Liu, Cheng-Zhi, Wang, Shao-Gang, Xia, Qi-Dong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 29.01.2025; BioMed Central; BMC
• Subjects: Androgen; Androgen suppression therapy; Care and treatment; Cohort Studies; Composition; Development and progression; Diagnosis; Gastrointestinal Microbiome - genetics; Genome-Wide Association Study; Gut; Humans; Male; Metagenome - genetics; Metastasis; Microbiome; Microbiota; Microbiota (Symbiotic organisms); Neoplasm Metastasis; Patient outcomes; Prostate cancer; Prostatic Neoplasms - genetics; Prostatic Neoplasms - microbiology; Prostatic Neoplasms - pathology; Treatment; China; Treatment; Androgen; Prostate cancer; Gut; Microbiome

Prostate cancer is one of the most common cancers in the United States with a high mortality rate. In recent years, the traditional opinion about prostate microbiome was challenged. Although there still are some arguments, an escalating number of researchers are shifting their focus toward the micro...