Cross-Reactivity Conferred by Homologous and Heterologous Prime-Boost A/H5 Influenza Vaccination Strategies in Humans: A Literature Review

• Published in: Vaccines (Basel) Vol. 9; no. 12; p. 1465
• Main Authors: Kok, Adinda, Fouchier, Ron A. M., Richard, Mathilde
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 10.12.2021; MDPI
• Subjects: Antibodies; Antigens; Aquatic birds; Avian flu; avian influenza A virus; Coronaviruses; COVID-19; Cross-reactivity; Datasets; Genetic diversity; Glycoproteins; H5 influenza virus; Hemagglutinins; Heterogeneity; Homology; Immune response (humoral); Immunogenicity; Immunology; Infections; Influenza; Literature reviews; pandemic; Pandemics; Review; Vaccination; Vaccines; Viruses; Zoonoses; zoonosis; avian influenza A virus; H5 influenza virus; pandemic; zoonosis; vaccination

Avian influenza viruses from the A/H5 A/goose/Guangdong/1/1996 (GsGd) lineage pose a continuing threat to animal and human health. Since their emergence in 1997, these viruses have spread across multiple continents and have become enzootic in poultry. Additionally, over 800 cases of human infection...