Mastocytosis

• Published in: Immunology and allergy clinics of North America Vol. 34; no. 1; p. 181
• Main Authors: Carter, Melody C, Metcalfe, Dean D, Komarow, Hirsh D
• Format: Journal Article
• Language: English
• Published: United States 01.02.2014
• Subjects: Disease Progression; Humans; Mastocytosis - diagnosis; Mastocytosis - etiology; Mastocytosis - therapy; Prognosis; Treatment Outcome; Bone marrow; Mastocytosis; Mast cell; Skin; Urticaria; KIT

Mastocytosis is a disorder of abnormal mast cell proliferation, with clinical features that include flushing, pruritus, abdominal pain, diarrhea, hypotension, syncope, and musculoskeletal pain. These features are the result of mast cell mediator release and infiltration into target organs. Patients...