Disposition of Drugs in Block Copolymer Micelle Delivery Systems From Discovery to Recovery

Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the therapeutic performance and modify the toxicity profile of encapsulated drugs by changing their pharmacokinetic characteristics. The efforts in t...

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Published inClinical pharmacokinetics Vol. 47; no. 10; pp. 619 - 634
Main Authors Aliabadi, Hamidreza Montazeri, Shahin, Mostafa, Brocks, Dion R., Lavasanifar, Afsaneh
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.01.2008
Adis international
Wolters Kluwer Health, Inc
Springer Nature B.V
Subjects
Animals
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - adverse effects
Biological and medical sciences
Drug Delivery Systems
General pharmacology
Humans
Internal Medicine
Leading Article
Medical sciences
Medicine
Medicine & Public Health
Micelles
Neoplasms - drug therapy
Pharmaceutical Preparations - administration & dosage
Pharmaceutical Preparations - metabolism
Pharmaceutical technology. Pharmaceutical industry
Pharmacokinetics
Pharmacology. Drug treatments
Pharmacology/Toxicology
Pharmacotherapy
Polymers
Tissue Distribution
Critical Micellar Concentration
Pluronic
Polymeric Micelle
Maximum Tolerable Dose
Paclitaxel
Human
Drug
Delivery system
Pharmacokinetic pharmacodynamic relationship
Micelle
Polymer
Review
Copolymer
Pharmacokinetics
Research and development
Online AccessGet full text

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Abstract Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the therapeutic performance and modify the toxicity profile of encapsulated drugs by changing their pharmacokinetic characteristics. The efforts in this area have led in recent years to the advancement of several polymeric micellar formulations to clinical trials, some of which have shown promise in changing the biodistribution of the incorporated drug after intravenous administration as a means of tumour-targeted drug delivery. Recently, the possible benefit of polymeric micellar delivery in enhancing the absorption and bioavailability of incorporated drugs from alternative routes of drug administration has attracted interest. This article provides an overview of the effect of polymeric micellar delivery on absorption, distribution, metabolism and excretion of incorporated therapeutic agents. It also aims to assess the current information on the performance of polymeric micellar delivery systems in modifying the pharmacokinetics/pharmacodynamics of the incorporated drugs in clinical trials, and to re-examine the important structural factors required for successful design of polymeric micellar delivery systems capable of inducing favourable changes in the pharmacokinetics of the encapsulated drug.
AbstractList Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the therapeutic performance and modify the toxicity profile of encapsulated drugs by changing their pharmacokinetic characteristics. The efforts in this area have led in recent years to the advancement of several polymeric micellar formulations to clinical trials, some of which have shown promise in changing the biodistribution of the incorporated drug after intravenous administration as a means of tumour-targeted drug delivery. Recently, the possible benefit of polymeric micellar delivery in enhancing the absorption and bioavailability of incorporated drugs from alternative routes of drug administration has attracted interest. This article provides an overview of the effect of polymeric micellar delivery on absorption, distribution, metabolism and excretion of incorporated therapeutic agents. It also aims to assess the current information on the performance of polymeric micellar delivery systems in modifying the pharmacokinetics/pharmacodynamics of the incorporated drugs in clinical trials, and to re-examine the important structural factors required for successful design of polymeric micellar delivery systems capable of inducing favourable changes in the pharmacokinetics of the encapsulated drug.
Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the therapeutic performance and modify the toxicity profile of encapsulated drugs by changing their pharmacokinetic characteristics. The efforts in this area have led in recent years to the advancement of several polymeric micellar formulations to clinical trials, some of which have shown promise in changing the biodistribution of the incorporated drug after intravenous administration as a means of tumour-targeted drug delivery. Recently, the possible benefit of polymeric micellar delivery in enhancing the absorption and bioavailability of incorporated drugs from alternative routes of drug administration has attracted interest. This article provides an overview of the effect of polymeric micellar delivery on absorption, distribution, metabolism and excretion of incorporated therapeutic agents. It also aims to assess the current information on the performance of polymeric micellar delivery systems in modifying the pharmacokinetics/pharmacodynamics of the incorporated drugs in clinical trials, and to re-examine the important structural factors required for successful design of polymeric micellar delivery systems capable of inducing favourable changes in the pharmacokinetics of the encapsulated drug.Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the therapeutic performance and modify the toxicity profile of encapsulated drugs by changing their pharmacokinetic characteristics. The efforts in this area have led in recent years to the advancement of several polymeric micellar formulations to clinical trials, some of which have shown promise in changing the biodistribution of the incorporated drug after intravenous administration as a means of tumour-targeted drug delivery. Recently, the possible benefit of polymeric micellar delivery in enhancing the absorption and bioavailability of incorporated drugs from alternative routes of drug administration has attracted interest. This article provides an overview of the effect of polymeric micellar delivery on absorption, distribution, metabolism and excretion of incorporated therapeutic agents. It also aims to assess the current information on the performance of polymeric micellar delivery systems in modifying the pharmacokinetics/pharmacodynamics of the incorporated drugs in clinical trials, and to re-examine the important structural factors required for successful design of polymeric micellar delivery systems capable of inducing favourable changes in the pharmacokinetics of the encapsulated drug.
Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the therapeutic performance and modify the toxicity profile of encapsulated drugs by changing their pharmacokinetic characteristics. The efforts in this area have led in recent years to the advancement of several polymeric micellar formulations to clinical trials, some of which have shown promise in changing the biodistribution of the incorporated drug after intravenous administration as a means of tumour-targeted drug delivery. Recently, the possible benefit of polymeric micellar delivery in enhancing the absorption and bioavailability of incorporated drugs from alternative routes of drug administration has attracted interest. This article provides an overview of the effect of polymeric micellar delivery on absorption, distribution, metabolism and excretion of incorporated therapeutic agents. It also alms to assess the current information on the performance of polymeric micellar delivery systems in modifying the pharmacokinetics/pharmacodynamics of the incorporated drugs in clinical trials, and to re-examine the important structural factors required for successful design of polymeric micellar delivery systems capable of inducing favourable changes in the pharmacokinetics of the encapsulated drug.
Audience Academic
Author Brocks, Dion R.
Lavasanifar, Afsaneh
Shahin, Mostafa
Aliabadi, Hamidreza Montazeri
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  givenname: Hamidreza Montazeri
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  fullname: Aliabadi, Hamidreza Montazeri
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  givenname: Mostafa
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  organization: Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta
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  organization: Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta
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Cites_doi 10.1016/S0168-3659(03)00094-4
10.1016/0168-3659(94)90203-8
10.1007/s11095-004-1188-0
10.1016/S0024-3205(00)00786-4
10.1007/s11095-006-0022-2
10.1016/j.jconrel.2005.03.018
10.1007/12_025
10.1021/bc950093n
10.1016/0169-409X(95)00029-7
10.1023/A:1016085108889
10.1016/S0169-409X(02)00017-0
10.1016/j.jconrel.2004.06.018
10.1016/j.vetimm.2007.05.011
10.1016/j.ijpharm.2006.08.018
10.2165/00003088-200140070-00005
10.1016/j.jconrel.2004.02.003
10.1016/S0168-3659(97)00124-7
10.1126/science.1095833
10.1016/0169-409X(95)00031-2
10.1002/(SICI)1099-081X(199710)18:7<623::AID-BDD46>3.0.CO;2-V
10.1016/j.ijpharm.2005.01.018
10.1038/sj.bjc.6602772
10.1016/j.ejpb.2006.09.002
10.1016/j.ijpharm.2006.10.016
10.1081/DDC-120001491
10.1351/pac200476071321
10.1007/BF02973916
10.1073/pnas.88.24.11460
10.1080/10611860500376741
10.1016/S1043-6618(03)00043-4
10.1002/jps.10397
10.1016/j.jconrel.2005.11.012
10.1002/jgm.1093
10.1021/bc034113u
10.1023/A:1018873702411
10.1016/0165-6147(94)90314-X
10.1016/j.jconrel.2006.10.001
10.1016/S0168-3659(01)00341-8
10.1023/B:PHAM.0000033005.25698.9c
10.1016/S0927-7765(99)00058-2
10.1016/j.ejpb.2006.11.010
10.1007/s002800050630
10.1023/A:1015127225021
10.1016/j.jconrel.2004.09.002
10.1021/bm0503165
10.1016/j.jconrel.2007.06.008
10.1016/S0169-409X(02)00015-7
10.1016/j.jconrel.2003.10.012
10.1016/S0378-5173(99)00339-7
10.1016/S0939-6411(99)00039-9
10.1023/A:1010908916184
10.1023/A:1024422625596
10.1023/A:1011942814300
10.1016/S0927-7765(99)00064-8
10.1016/j.ijpharm.2007.04.013
10.1038/sj.gt.3301485
10.1089/10430340460745801
10.1016/j.jconrel.2006.09.046
10.1016/S0168-3659(01)00299-1
10.1002/1097-0045(20000701)44:2<156::AID-PROS8>3.0.CO;2-8
10.1016/0005-2736(91)90182-8
10.1007/s10549-007-9591-y
10.1016/0168-3659(94)90118-X
10.1038/sj.bjc.6603311
10.1124/jpet.102.043307
10.1016/0005-2736(91)90246-5
10.2165/00003088-200342050-00002
10.1016/j.plipres.2004.09.001
10.1038/sj.bjc.6602479
10.1016/j.jconrel.2006.12.007
10.1016/S0169-409X(02)00019-4
10.1208/ps040440
10.1211/jpp.58.7.0004
10.1158/0008-5472.CAN-06-1605
10.1080/03639040701397381
10.1016/S0142-9612(00)00393-8
10.1016/S0378-5173(01)00825-0
10.2165/00003495-199700544-00004
10.1038/bjc.1996.587
10.1615/CritRevTherDrugCarrierSyst.v20.i5.20
10.1021/bm060307b
10.1023/A:1018942823676
10.2165/00137696-200402010-00002
10.1007/s00396-004-1243-8
10.1016/S0939-6411(02)00119-4
10.1097/00001813-199708000-00008
10.1016/S0168-3659(01)00477-1
10.1016/S0169-409X(00)00124-1
10.1016/j.jconrel.2004.06.003
10.1021/bc950089b
10.1016/0005-2736(89)90078-3
10.1016/j.ijpharm.2006.09.030
10.1158/1078-0432.CCR-03-0655
10.1208/pt0801001
10.1016/S0168-3659(99)00133-9
10.1016/S0378-5173(00)00443-9
10.1093/annonc/mdm374
10.1016/S0378-5173(00)00508-1
10.1080/03639040500214662
10.1016/S0169-409X(96)00401-2
10.1016/j.ijpharm.2005.04.016
10.1016/j.jconrel.2004.08.022
10.1038/sj.bjc.6602204
10.1023/A:1011964213024
10.1016/j.ijpharm.2006.06.040
10.1007/BF02980249
10.1016/j.biomaterials.2006.08.004
10.1016/S0163-7827(03)00033-X
10.1080/10611860400011927
10.1016/S0168-3659(97)00163-6
10.1517/17425247.3.1.139
10.1080/10611860701538586
10.1016/S0024-3205(99)00111-3
10.1016/j.ejpb.2007.03.022
10.1007/BF02974636
10.1016/S0169-409X(01)00242-3
10.1023/A:1018998203127
10.1016/j.jconrel.2004.10.022
10.1021/bc00036a001
10.3109/10611869909085500
10.1038/sj.bjc.6603855
10.1016/S0168-3659(01)00275-9
10.1016/j.ultras.2004.01.087
10.1007/s00018-004-4153-5
10.1016/0168-3659(94)90237-2
10.1021/ja039651w
10.1111/j.1745-7254.2006.00340.x
10.1023/A:1022286422439
10.1016/j.intimp.2007.05.003
10.1111/j.1349-7006.2001.tb01099.x
10.1016/j.jconrel.2005.02.010
10.1081/PDT-100102035
10.2174/1567201052772852
10.1016/j.jconrel.2004.12.018
10.1016/0378-5173(95)04386-1
10.1016/j.ijpharm.2006.10.002
10.1615/CritRevTherDrugCarrierSyst.v15.i5.20
10.1016/0168-3659(90)90139-K
10.1093/ajhp/61.23.2541
10.1016/0168-3659(93)90172-2
10.1016/j.biomaterials.2005.05.042
10.1038/sj.bjc.6601856
10.1002/marc.1987.030080903
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IngestDate Tue Aug 05 10:17:41 EDT 2025
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IsPeerReviewed true
IsScholarly true
Issue 10
Keywords Critical Micellar Concentration
Pluronic
Polymeric Micelle
Maximum Tolerable Dose
Paclitaxel
Human
Drug
Delivery system
Pharmacokinetic pharmacodynamic relationship
Micelle
Polymer
Review
Copolymer
Pharmacokinetics
Research and development
Language English
License CC BY 4.0
LinkModel DirectLink
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content type line 14
ObjectType-Review-3
content type line 23
PMID 18783294
PQID 222742643
PQPubID 32335
PageCount 16
ParticipantIDs proquest_miscellaneous_69539166
proquest_journals_222742643
gale_infotracmisc_A199864175
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pubmed_primary_18783294
pascalfrancis_primary_20743735
crossref_primary_10_2165_00003088_200847100_00001
crossref_citationtrail_10_2165_00003088_200847100_00001
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ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2008-01-01
PublicationDateYYYYMMDD 2008-01-01
PublicationDate_xml – month: 01
  year: 2008
  text: 2008-01-01
  day: 01
PublicationDecade 2000
PublicationPlace Cham
PublicationPlace_xml – name: Cham
– name: Auckland
– name: Switzerland
PublicationTitle Clinical pharmacokinetics
PublicationTitleAbbrev Clin Pharmacokinet
PublicationTitleAlternate Clin Pharmacokinet
PublicationYear 2008
Publisher Springer International Publishing
Adis international
Wolters Kluwer Health, Inc
Springer Nature B.V
Publisher_xml – name: Springer International Publishing
– name: Adis international
– name: Wolters Kluwer Health, Inc
– name: Springer Nature B.V
References Allen, Eisenberg, Maysinger (CR11) 1999; 9
Yoo, Park (CR109) 2004; 96
Alakhov, Klinski, Li (CR85) 1999; 16
Uchino, Matsumura, Negishi (CR91) 2005; 93
Carafa, Marianecci, Annibaldi (CR34) 2006; 325
Chang, Chang, Tong (CR24) 2004; 15
Jagannath, Wells, Mshvildadze (CR59) 1999; 64
Kim, Kim, Shim (CR99) 2001; 72
Kwon (CR16) 2003; 20
Foger, Hoyer, Kafedjiiski (CR47) 2006; 27
Richards, Thomas, Bowen (CR65) 2006; 58
Kumar, Chen, Parmar (CR69) 2004; 126
Tamilvanan (CR73) 2004; 43
Batrakova, Li, Alakhov (CR150) 2003; 304
Valle, Lawrance, Brewer (CR151) 2004; 22
Adams, Lavasanifar, Kwon (CR10) 2003; 92
Nishiyama, Okazaki, Cabral (CR118) 2003; 63
Lavasanifar, Samuel, Sattari (CR132) 2002; 19
Han, Guo, Zhang (CR116) 2006; 27
Torchilin (CR23) 2001; 73
Ould-Ouali, Noppe, Langlois (CR51) 2005; 102
Vinogradov, Batrakova, Li (CR49) 2004; 12
Dowling, Arjomand, Lin (CR61) 2004; 61
Kim, Shin, Lee (CR134) 1998; 51
Seeballuck, Ashford, O’Driscoll (CR48) 2003; 20
Matsumura, Hamaguchi, Ura (CR89) 2004; 91
Kwon, Kataoka (CR6) 1995; 16
Lee, Na, Bae (CR111) 2005; 103
Fundueanu, Constantin, Bortolotti (CR40) 2007; 66
Hamaguchi, Kato, Yasui (CR87) 2007; 97
Kwon, Suwa, Yokohama (CR104) 1994; 29
Aliabadi, Elhasi, Mahmud (CR128) 2007; 329
Kim, Lee, Vaishali (CR37) 2005; 105
Hathout, Mansour, Mortada (CR76) 2007; 8
Kim, Lee, Shin (CR123) 2001; 22
Kataoka, Kwon, Yokoyama (CR14) 1993; 24
Allen, Cullis (CR4) 2004; 303
Aliabadi, Brocks, Lavasanifar (CR83) 2005; 26
Yokoyama, Okano, Sakurai (CR103) 1991; 51
Liaw, Chang, Hsiao (CR78) 2001; 8
Danson, Ferry, Alakhov (CR86) 2004; 90
Dhanikula, Singh, Panchagnula (CR98) 2005; 2
Chiappetta, Sosnik (CR26) 2007; 66
CR141
Yang, Pan, Sun (CR39) 2007; 119
Klang, Abdulrazik, Benita (CR71) 2000; 5
Yokoyama (CR9) 1992; 9
Mathot, Van Beijsterveldt, Preat (CR52) 2006; 111
Miller, Batrakova, Kabanov (CR148) 1999; 16
Gabizon, Shmeeda, Barenholz (CR93) 2003; 42
Kwon (CR15) 1998; 15
Cilek, Celebi, Tirnaksiz (CR36) 2005; 298
Liu, Mori, Huang (CR126) 1991; 1066
Kataoka, Matsumoto, Yokoyama (CR108) 2000; 64
Aliabadi, Lavasanifar (CR1) 2006; 3
Kabanov, Vinogradov, Suzdaltseva (CR13) 1995; 6
Woo, Lee, Shim (CR55) 2003; 20
Banerjee, Jagannath, Hunter (CR58) 2000; 67
Jette, Law, Schmitt (CR133) 2004; 21
Johnson, Charman, Porter (CR57) 2002; 4
Le Garrec, Gori, Luo (CR100) 2004; 99
Nah, Paek, Jeong (CR130) 1998; 21
Kim, Kim, Chung (CR115) 2004; 10
Allen, Hansen, Lopes de Menezes (CR81) 1995; 16
Kataoka, Harada, Nagasaki (CR5) 2001; 47
Cabral, Nishiyama, Okazaki (CR119) 2005; 101
Kwon, Kim, Ha (CR30) 2007; 30
Lu, Wen, Yang (CR41) 2007; 333
Zhang, Burt, Von Hoff (CR112) 1997; 40
Zastre, Jackson, Bajwa (CR50) 2002; 54
Lee, Cho, Cho (CR131) 2004; 94
Yokoyama, Okano, Sakurai (CR105) 1999; 7
Kwon, Okano (CR7) 1996; 21
Francis, Cristea, Winnik (CR28) 2004; 76
Le Garrec, Ranger, Leroux (CR18) 2004; 2
Nishiyama, Kato, Sugiyama (CR90) 2001; 18
Zhang, Jackson, Burt (CR152) 1996; 132
Peltier, Oger, Lagarce (CR56) 2006; 23
Lee, Huh, Lee (CR53) 2007; 8
Kakizawa, Kataoka (CR21) 2002; 54
Nakanishi, Fukushima, Okamoto (CR106) 2001; 74
Budai, Hajdu, Budai (CR75) 2007; 343
Yokoyama, Okano, Sakurai (CR140) 1994; 32
Vyas, Mysore, Jaitely (CR74) 1998; 53
Kwon, Suwa, Yokoyama (CR127) 1994; 28
Allen (CR3) 1994; 15
Kim, Kim, Kim (CR142) 2007; 18
Allen (CR2) 1997; 54
Desai, Labhasetwar, Amidon (CR45) 1996; 13
Shin, Cho (CR66) 2006; 29
Gao, Lee, Kim (CR110) 2005; 13
Shin, Cho, Oh (CR32) 2000; 193
Allen, Hansen, Martin (CR92) 1991; 1066
Chao, Chang, Lu (CR25) 2007; 118
Stamatialis, Rolevink, Koops (CR67) 2006; 116
Escobar-Chavez, Quintanar-Guerrero, Ganem-Quintanar (CR62) 2005; 31
Harris, Martin, Modi (CR94) 2001; 40
Negishi, Koizumi, Uchino (CR153) 2006; 95
Kwon (CR29) 2005
Yi, Yoon, Kim (CR54) 2007; 117
Jeong, Cheon, Kim (CR129) 1998; 51
Hamaguchi, Matsumura, Suzuki (CR88) 2005; 92
Nishiyama, Kataoka (CR84) 2006; 193
Lavasanifar, Samuel, Kwon (CR135) 2001; 77
Yoncheva, Guembe, Campanero (CR44) 2007; 334
Nair, Panchagnula (CR63) 2003; 47
Sznitowska, Zurowska-Pryczkowska, Dabrowska (CR72) 2000; 202
Batrakova, Lee, Li (CR149) 1999; 16
Venne, Li, Mandeville (CR146) 1996; 56
Sezgin, Yuksel, Baykara (CR43) 2007; 332
Shuai, Ai, Nasongkla (CR136) 2004; 98
Pillai, Panchagnula (CR64) 2003; 89
Bogdanov, Martin, Bogdanova (CR120) 1996; 7
Batrakova, Han, Miller (CR46) 1998; 15
Lee, Chung, Im (CR143) 2008; 108
Torchilin (CR22) 2002; 54
Zhang, Ping, Huang (CR35) 2005; 294
Rapoport, Christensen, Fain (CR107) 2004; 42
Sant, Smith, Leroux (CR31) 2005; 104
Papahadjopoulos, Allen, Gabizon (CR124) 1991; 88
Suh, Jun, Dzimianski (CR68) 1997; 18
Alakhov, Moskaleva, Batrakova (CR144) 1996; 7
Yokoyama, Miyauchi, Yamada (CR139) 1990; 50
Jeong, Kim, Bae (CR60) 2002; 54
Yokoyama, Inoue, Kataoka (CR138) 1987; 8
Aliabadi, Brocks, Mahdipoor (CR82) 2007; 122
Allen, Hansen, Rutledge (CR125) 1989; 981
Liu, Zeng, Allen (CR97) 2007; 65
Shuai, Merdan, Schaper (CR137) 2004; 15
Sun, Pan, Yang (CR38) 2007; 7
Batrakova, Li, Li (CR96) 2004; 100
Kwon, Yokoyama, Okano (CR102) 1993; 10
Francis, Cristea, Yang (CR42) 2005; 22
Batrakova, Dorodnych, Klinskii (CR145) 1996; 74
Allen, Maysinger, Eisenberg (CR12) 1999; 16
Moghimi, Szebeni (CR95) 2003; 42
Lavasanifar, Samuel, Kwon (CR17) 2002; 54
Zhang, Burt, Mangold (CR113) 1997; 8
Yokoyama, Miyauchi, Yamada (CR101) 1990; 11
Tong, Chang, Liu (CR33) 2007; 9
Mizumura, Matsumura, Hamaguchi (CR117) 2001; 92
Miyazaki, Suzuki, Kawasaki (CR70) 2001; 229
Mahmud, Xiong, Aliabadi (CR19) 2007; 15
Jones, Leroux (CR20) 1999; 48
Gupta, Madan, Majumdar (CR77) 2000; 209
Francis, Cristea, Winnik (CR27) 2005; 6
Tu, Pang, Yan (CR80) 2007; 33
Carmignani, Rossi, Saettone (CR79) 2002; 28
Shi, Fang, You (CR121) 2005; 283
Batrakova, Han, Alakhov (CR147) 1998; 15
Koizumi, Kitagawa, Negishi (CR122) 2006; 66
Torchilin (CR8) 2004; 61
Leung, Jackson, Miyake (CR114) 2000; 44
Allen (R81-1-20080912) 1995; 16
Lavasanifar (R132-1-20080912) 2002; 19
Carmignani (R79-1-20080912) 2002; 28
Seeballuck (R48-1-20080912) 2003; 20
Torchilin (R23-1-20080912) 2001; 73
Yokoyama (R9-1-20080912) 1992; 9
LeGarrec (R18-1-20080912) 2004; 2
Francis (R27-1-20080912) 2005; 6
Kataoka (R108-1-20080912) 2000; 64
Batrakova (R96-1-20080912) 2004; 100
Lavasanifar (R17-1-20080912) 2002; 54
Negishi (R153-1-20080912) 2006; 95
Allen (R11-1-20080912) 1999; 9
Sznitowska (R72-1-20080912) 2000; 202
Desai (R45-1-20080912) 1996; 13
Zhang (R35-1-20080912) 2005; 294
Kim (R115-1-20080912) 2004; 10
Kakizawa (R21-1-20080912) 2002; 54
Papahadjopoulos (R124-1-20080912) 1991; 88
Batrakova (R147-1-20080912) 1998; 15
Koizumi (R122-1-20080912) 2006; 66
Yoncheva (R44-1-20080912) 2007; 334
Kwon (R102-1-20080912) 1993; 10
Jette (R133-1-20080912) 2004; 21
BogdanovJr (R120-1-20080912) 1996; 7
Hathout (R76-1-20080912) 2007; 8
Lee (R111-1-20080912) 2005; 103
Harris (R94-1-20080912) 2001; 40
Kwon (R6-1-20080912) 1995; 16
Torchilin (R8-1-20080912) 2004; 61
Kataoka (R5-1-20080912) 2001; 47
Shuai (R137-1-20080912) 2004; 15
Batrakova (R46-1-20080912) 1998; 15
Ould-Ouali (R51-1-20080912) 2005; 102
Kwon (R127-1-20080912) 1994; 28
Nair (R63-1-20080912) 2003; 47
Fundueanu (R40-1-20080912) 2007; 66
Tu (R80-1-20080912) 2007; 33
Aliabadi (R128-1-20080912) 2007; 329
Budai (R75-1-20080912) 2007; 343
Batrakova (R150-1-20080912) 2003; 304
Kim (R99-1-20080912) 2001; 72
Hamaguchi (R87-1-20080912) 2007; 97
Richards (R65-1-20080912) 2006; 58
Aliabadi (R82-1-20080912) 2007; 122
Alakhov (R85-1-20080912) 1999; 16
Francis (R42-1-20080912) 2005; 22
Matsumura (R89-1-20080912) 2004; 91
Klang (R71-1-20080912) 2000; 5
Kataoka (R14-1-20080912) 1993; 24
Rapoport (R107-1-20080912) 2004; 42
Dowling (R61-1-20080912) 2004; 61
Kabanov (R13-1-20080912) 1995; 6
Alakhov (R144-1-20080912) 1996; 7
Miyazaki (R70-1-20080912) 2001; 229
Zhang (R152-1-20080912) 1996; 132
Kwon (R15-1-20080912) 1998; 15
Johnson (R57-1-20080912) 2002; 4
Zhang (R112-1-20080912) 1997; 40
Venne (R146-1-20080912) 1996; 56
Francis (R28-1-20080912) 2004; 76
Dhanikula (R98-1-20080912) 2005; 2
Allen (R125-1-20080912) 1989; 981
Kwon (R16-1-20080912) 2003; 20
Han (R116-1-20080912) 2006; 27
Mizumura (R117-1-20080912) 2001; 92
Tamilvanan (R73-1-20080912) 2004; 43
Peltier (R56-1-20080912) 2006; 23
Cabral (R119-1-20080912) 2005; 101
Aliabadi (R1-1-20080912) 2006; 3
Kim (R134-1-20080912) 1998; 51
Sun (R38-1-20080912) 2007; 7
Kwon (R7-1-20080912) 1996; 21
Tong (R33-1-20080912) 2007; 9
Gupta (R77-1-20080912) 2000; 209
Shin (R66-1-20080912) 2006; 29
LeGarrec (R100-1-20080912) 2004; 99
Adams (R10-1-20080912) 2003; 92
Liu (R126-1-20080912) 1991; 1066
Yang (R39-1-20080912) 2007; 119
Mathot (R52-1-20080912) 2006; 111
Cilek (R36-1-20080912) 2005; 298
Carafa (R34-1-20080912) 2006; 325
Shuai (R136-1-20080912) 2004; 98
Yokoyama (R140-1-20080912) 1994; 32
Allen (R12-1-20080912) 1999; 16
Allen (R3-1-20080912) 1994; 15
Vinogradov (R49-1-20080912) 2004; 12
Allen (R92-1-20080912) 1991; 1066
Batrakova (R145-1-20080912) 1996; 74
Yokoyama (R103-1-20080912) 1991; 51
Stamatialis (R67-1-20080912) 2006; 116
Nishiyama (R84-1-20080912) 2006; 193
Shin (R32-1-20080912) 2000; 193
Nishiyama (R90-1-20080912) 2001; 18
Lavasanifar (R135-1-20080912) 2001; 77
Zhang (R113-1-20080912) 1997; 8
Sant (R31-1-20080912) 2005; 104
Uchino (R91-1-20080912) 2005; 93
Shi (R121-1-20080912) 2005; 283
Kim (R37-1-20080912) 2005; 105
Leung (R114-1-20080912) 2000; 44
Lee (R143-1-20080912) 2008; 108
Chiappetta (R26-1-20080912) 2007; 66
Yokoyama (R138-1-20080912) 1987; 8
Mahmud (R19-1-20080912) 2007; 15
Kumar (R69-1-20080912) 2004; 126
Lu (R41-1-20080912) 2007; 333
Vyas (R74-1-20080912) 1998; 53
Chao (R25-1-20080912) 2007; 118
Jagannath (R59-1-20080912) 1999; 64
Liaw (R78-1-20080912) 2001; 8
Hamaguchi (R88-1-20080912) 2005; 92
Jeong (R60-1-20080912) 2002; 54
Moghimi (R95-1-20080912) 2003; 42
Zastre (R50-1-20080912) 2002; 54
Lee (R131-1-20080912) 2004; 94
Aliabadi (R83-1-20080912) 2005; 26
Banerjee (R58-1-20080912) 2000; 67
Liu (R97-1-20080912) 2007; 65
Jeong (R129-1-20080912) 1998; 51
Yokoyama (R139-1-20080912) 1990; 50
Jones (R20-1-20080912) 1999; 48
Miller (R148-1-20080912) 1999; 16
Nishiyama (R118-1-20080912) 2003; 63
Pillai (R64-1-20080912) 2003; 89
Nakanishi (R106-1-20080912) 2001; 74
Suh (R68-1-20080912) 1997; 18
Gao (R110-1-20080912) 2005; 13
Yokoyama (R101-1-20080912) 1990; 11
Allen (R4-1-20080912) 2004; 303
Kwon (R30-1-20080912) 2007; 30
Yokoyama (R105-1-20080912) 1999; 7
Escobar-Chavez (R62-1-20080912) 2005; 31
Gabizon (R93-1-20080912) 2003; 42
Sezgin (R43-1-20080912) 2007; 332
Foger (R47-1-20080912) 2006; 27
Kwon (R104-1-20080912) 1994; 29
Yoo (R109-1-20080912) 2004; 96
Yi (R54-1-20080912) 2007; 117
Nah (R130-1-20080912) 1998; 21
Lee (R53-1-20080912) 2007; 8
Woo (R55-1-20080912) 2003; 20
Batrakova (R149-1-20080912) 1999; 16
Kim (R142-1-20080912) 2007; 18
Torchilin (R22-1-20080912) 2002; 54
Chang (R24-1-20080912) 2004; 15
Danson (R86-1-20080912) 2004; 90
Kim (R123-1-20080912) 2001; 22
16093210 - Drug Dev Ind Pharm. 2005 May;31(4-5):447-54
15925422 - J Control Release. 2005 Jun 20;105(1-2):32-42
17481869 - Eur J Pharm Biopharm. 2007 Jun;66(3):303-17
17008034 - Int J Pharm. 2007 Feb 1;329(1-2):158-65
10353627 - Life Sci. 1999;64(19):1733-8
15763623 - J Control Release. 2005 Mar 21;103(2):405-18
17852364 - Drug Dev Ind Pharm. 2007 Oct;33(10):1142-50
11516494 - J Control Release. 2001 Jun 15;73(2-3):137-72
10881025 - Prostate. 2000 Jul 1;44(2):156-63
2065067 - Biochim Biophys Acta. 1991 Jul 1;1066(1):29-36
11858520 - Drug Dev Ind Pharm. 2002 Jan;28(1):101-5
15783068 - Pharm Res. 2005 Feb;22(2):209-19
17724775 - J Gene Med. 2007 Nov;9(11):956-66
17718968 - J Control Release. 2006 Nov 28;116(2):e53-5
9875469 - Arch Pharm Res. 1998 Aug;21(4):418-22
15950411 - Int J Pharm. 2005 Jul 14;298(1):176-85
10213370 - Pharm Res. 1999 Mar;16(3):396-401
17476588 - Breast Cancer Res Treat. 2008 Mar;108(2):241-50
14695216 - Cancer Res. 2003 Dec 15;63(24):8977-83
15522762 - Prog Lipid Res. 2004 Nov;43(6):489-533
15150584 - Br J Cancer. 2004 Jun 1;90(11):2085-91
9685914 - J Control Release. 1998 Feb 12;51(2-3):169-78
15681087 - J Control Release. 2005 Feb 16;102(3):657-68
12739982 - Clin Pharmacokinet. 2003;42(5):419-36
16919723 - Biomaterials. 2006 Dec;27(34):5855-60
15621677 - J Drug Target. 2004;12(8):517-26
16222314 - Br J Cancer. 2005 Sep 19;93(6):678-87
9311446 - Anticancer Drugs. 1997 Aug;8(7):696-701
15907580 - J Control Release. 2005 May 18;104(2):289-300
16805949 - J Pharm Pharmacol. 2006 Jul;58(7):903-8
15526161 - Cell Mol Life Sci. 2004 Oct;61(19-20):2549-59
16308207 - J Drug Target. 2005 Aug;13(7):391-7
15144578 - Hum Gene Ther. 2004 May;15(5):481-93
7940982 - Trends Pharmacol Sci. 1994 Jul;15(7):215-20
12742011 - Pharmacol Res. 2003 Jun;47(6):555-62
8932333 - Br J Cancer. 1996 Nov;74(10 ):1545-52
11072877 - Life Sci. 2000 Sep 8;67(16):2011-6
11426885 - Biomaterials. 2001 Jul;22(14):2049-56
8608176 - Bioconjug Chem. 1995 Nov-Dec;6(6):639-43
11084241 - Int J Pharm. 2000 Nov 19;209(1-2):1-14
11438834 - Gene Ther. 2001 Jul;8(13):999-1004
12538842 - J Pharmacol Exp Ther. 2003 Feb;304(2):845-54
16005061 - Biomaterials. 2005 Dec;26(35):7251-9
10606784 - Int J Pharm. 2000 Jan 5;193(2):213-8
17047068 - Cancer Res. 2006 Oct 15;66(20):10048-56
16370946 - Expert Opin Drug Deliv. 2006 Jan;3(1):139-62
1763060 - Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11460-4
17644207 - J Control Release. 2007 Sep 11;122(1):63-70
15047411 - Ultrasonics. 2004 Apr;42(1-9):943-50
10469928 - Eur J Pharm Biopharm. 1999 Sep;48(2):101-11
14559067 - Prog Lipid Res. 2003 Nov;42(6):463-78
17628697 - Vet Immunol Immunopathol. 2007 Oct 15;119(3-4):299-302
17968711 - J Drug Target. 2007 Nov;15(9):553-84
15327322 - J Am Chem Soc. 2004 Sep 1;126(34):10640-4
10640653 - J Control Release. 2000 Feb 14;64(1-3):143-53
9647349 - Pharm Res. 1998 Jun;15(6):850-5
9330782 - Biopharm Drug Dispos. 1997 Oct;18(7):623-33
11897144 - Adv Drug Deliv Rev. 2002 Feb 21;54(2):169-90
17081709 - Int J Pharm. 2007 Mar 21;333(1-2):87-94
16909136 - Br J Cancer. 2006 Sep 4;95(5):601-6
9361956 - Drugs. 1997;54 Suppl 4:8-14
16723095 - Acta Pharmacol Sin. 2006 Jun;27(6):747-53
12445560 - Eur J Pharm Biopharm. 2002 Nov;54(3):299-309
11389998 - J Control Release. 2001 May 14;72(1-3):191-202
15342183 - J Control Release. 2004 Sep 14;99(1):83-101
15588907 - J Control Release. 2005 Jan 3;101(1-3):223-32
17097755 - J Control Release. 2007 Jan 22;117(1):59-67
8378259 - Pharm Res. 1993 Jul;10(7):970-4
16884870 - Int J Pharm. 2006 Nov 15;325(1-2):155-62
15567504 - J Control Release. 2004 Dec 10;100(3):389-97
17958332 - Arch Pharm Res. 2007 Sep;30(9):1138-43
12033373 - Pharm Res. 2002 Apr;19(4):418-22
9742041 - Pharmazie. 1998 Jul;53(7):466-9
17257817 - Eur J Pharm Biopharm. 2007 Mar;65(3):309-19
15814248 - Int J Pharm. 2005 Apr 27;294(1-2):247-59
11604255 - Int J Pharm. 2001 Oct 23;229(1-2):29-36
1458544 - Crit Rev Ther Drug Carrier Syst. 1992;9(3-4):213-48
15312997 - J Control Release. 2004 Aug 27;98 (3):415-26
9137535 - Cancer Chemother Pharmacol. 1997;40(1):81-6
10915939 - Int J Pharm. 2000 Jul 20;202(1-2):161-4
15290858 - Pharm Res. 2004 Jul;21(7):1184-91
12608532 - Pharm Res. 2003 Jan;20(1):24-30
12820139 - J Pharm Sci. 2003 Jul;92(7):1343-55
8742003 - Bioconjug Chem. 1996 Jan-Feb;7(1):144-9
11496942 - Pharm Res. 2001 Jul;18(7):1035-41
11689268 - J Control Release. 2001 Nov 9;77(1-2):155-60
2719971 - Biochim Biophys Acta. 1989 May 19;981(1):27-35
17785767 - Ann Oncol. 2007 Dec;18(12):2009-14
11489509 - J Control Release. 2001 Jul 6;74(1-3):295-302
17595665 - Br J Cancer. 2007 Jul 16;97(2):170-6
9794493 - Pharm Res. 1998 Oct;15(10):1525-32
15149170 - Bioconjug Chem. 2004 May-Jun;15(3):441-8
16715372 - Pharm Res. 2006 Jun;23(6):1243-50
2306723 - Cancer Res. 1990 Mar 15;50(6):1693-700
16460829 - J Control Release. 2006 Mar 10;111(1-2):47-55
9685900 - J Control Release. 1998 Jan 23;51(1):13-22
17537601 - Int J Pharm. 2007 Oct 1;343(1-2):34-40
15477860 - Br J Cancer. 2004 Nov 15;91(10):1775-81
17118588 - Int J Pharm. 2007 Apr 4;334(1-2):156-65
17258837 - J Control Release. 2007 Mar 12;118(1):105-17
11251249 - Adv Drug Deliv Rev. 2001 Mar 23;47(1):113-31
15173077 - Clin Cancer Res. 2004 Jun 1;10(11):3708-16
14744484 - J Control Release. 2004 Feb 10;94(2-3):323-35
12880295 - Pharm Res. 2003 Jul;20(7):1085-92
11109251 - Pharm Dev Technol. 2000;5(4):521-32
17055200 - Int J Pharm. 2007 Mar 6;332(1-2):161-7
12695068 - J Control Release. 2003 Apr 14;89(1):127-40
14959789 - Crit Rev Ther Drug Carrier Syst. 2003;20(5):357-403
11897148 - Adv Drug Deliv Rev. 2002 Feb 21;54(2):235-52
8983343 - Bioconjug Chem. 1996 Mar-Apr;7(2):209-16
10680973 - J Drug Target. 1999;7(3):171-86
2039998 - Cancer Res. 1991 Jun 15;51(12):3229-36
15031496 - Science. 2004 Mar 19;303(5665):1818-22
11267944 - Jpn J Cancer Res. 2001 Mar;92(3):328-36
11897146 - Adv Drug Deliv Rev. 2002 Feb 21;54(2):203-22
15785749 - Br J Cancer. 2005 Apr 11;92(7):1240-6
15081218 - J Control Release. 2004 Apr 28;96(2):273-83
17121190 - Arch Pharm Res. 2006 Oct;29(10):928-33
17085025 - Eur J Pharm Biopharm. 2007 Apr;66(1):11-20
9822868 - Crit Rev Ther Drug Carrier Syst. 1998;15(5):481-512
16153081 - Biomacromolecules. 2005 Sep-Oct;6(5):2462-7
1854781 - Biochim Biophys Acta. 1991 Jul 22;1066(2):159-65
17630205 - Int Immunopharmacol. 2007 Sep;7(9):1259-64
11510630 - Clin Pharmacokinet. 2001;40(7):539-51
8987081 - Pharm Res. 1996 Dec;13(12):1838-45
8705995 - Cancer Res. 1996 Aug 15;56(16):3626-9
11755705 - Adv Drug Deliv Rev. 2002 Jan 17;54(1):37-51
15595229 - Am J Health Syst Pharm. 2004 Dec 1;61(23):2541-4
17206808 - Biomacromolecules. 2007 Jan;8(1):202-8
12646011 - AAPS PharmSci. 2002;4(4):E40
16305406 - Curr Drug Deliv. 2005 Jan;2(1):35-44
10496652 - Pharm Res. 1999 Sep;16(9):1373-9
17408209 - AAPS PharmSciTech. 2007 Jan 05;8(1):1
References_xml – volume: 89
  start-page: 127
  issue: 1
  year: 2003
  end-page: 40
  ident: CR64
  article-title: Transdermal delivery of insulin from poloxamer gel: ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(03)00094-4
– volume: 28
  start-page: 334
  issue: 1–3
  year: 1994
  end-page: 5
  ident: CR127
  article-title: Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(94)90203-8
– volume: 22
  start-page: 209
  issue: 2
  year: 2005
  end-page: 19
  ident: CR42
  article-title: Engineering polysaccharide-based polymeric micelles to enhance permeability of cyclosporin A across Caco-2 cells
  publication-title: Pharm Res
  doi: 10.1007/s11095-004-1188-0
– volume: 67
  start-page: 2011
  issue: 16
  year: 2000
  end-page: 6
  ident: CR58
  article-title: Bioavailability of tobramycin after oral delivery in FVB mice using CRL-1605 copolymer, an inhibitor of P-glycoprotein
  publication-title: Life Sci
  doi: 10.1016/S0024-3205(00)00786-4
– volume: 23
  start-page: 1243
  issue: 6
  year: 2006
  end-page: 50
  ident: CR56
  article-title: Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded lipid nanocapsules
  publication-title: Pharm Res
  doi: 10.1007/s11095-006-0022-2
– volume: 105
  start-page: 32
  issue: 1–2
  year: 2005
  end-page: 42
  ident: CR37
  article-title: Tricaprylin microemulsion for oral delivery of low molecular weight heparin conjugates
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2005.03.018
– volume: 193
  start-page: 67
  year: 2006
  end-page: 101
  ident: CR84
  article-title: Nanostructured devices based on block copolymer assemblies for drug delivery: designing structures for enhanced drug function
  publication-title: Adv Polym Sci
  doi: 10.1007/12_025
– volume: 8
  start-page: 431
  year: 1987
  end-page: 5
  ident: CR138
  article-title: Preparation of adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: a new type of polymeric anticancer agent
  publication-title: Makromol Chem
– volume: 7
  start-page: 209
  issue: 2
  year: 1996
  end-page: 16
  ident: CR144
  article-title: Hypersensitization of multidrug resistant human ovarian carcinoma cells by Pluronic P85 block copolymer
  publication-title: Bioconjug Chem
  doi: 10.1021/bc950093n
– volume: 16
  start-page: 267
  issue: 2–3
  year: 1995
  end-page: 84
  ident: CR81
  article-title: Pharmacokinetics of long circulating liposomes
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/0169-409X(95)00029-7
– volume: 13
  start-page: 1838
  issue: 12
  year: 1996
  end-page: 45
  ident: CR45
  article-title: Gastrointestinal uptake of biodegradable microparticles: effect of particle size
  publication-title: Pharm Res
  doi: 10.1023/A:1016085108889
– volume: 54
  start-page: 203
  issue: 2
  year: 2002
  end-page: 22
  ident: CR21
  article-title: Block copolymer micelles for delivery of gene and related compounds
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(02)00017-0
– volume: 99
  start-page: 83
  issue: 1
  year: 2004
  end-page: 101
  ident: CR100
  article-title: Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.06.018
– volume: 119
  start-page: 299
  issue: 3–4
  year: 2007
  end-page: 302
  ident: CR39
  article-title: The immune response and protective efficacy of oral alginate microparticle vaccine in soft-shelled turtles ( )
  publication-title: Vet Immunol and Immunopathol
  doi: 10.1016/j.vetimm.2007.05.011
– volume: 24
  start-page: 119
  issue: 1–3
  year: 1993
  end-page: 32
  ident: CR14
  article-title: Block copolymer micelles as vehicles for drug delivery
  publication-title: J Control Rel
– volume: 329
  start-page: 158
  year: 2007
  end-page: 65
  ident: CR128
  article-title: Encapsulation of hydrophobic drugs in polymeric micelles through co-solvent evaporation: the effect of solvent composition on micellar properties and drug loading
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.08.018
– volume: 40
  start-page: 539
  issue: 7
  year: 2001
  end-page: 51
  ident: CR94
  article-title: Pegylation: a novel process for modifying pharmacokinetics
  publication-title: Clin Pharmacokinet
  doi: 10.2165/00003088-200140070-00005
– volume: 96
  start-page: 273
  issue: 2
  year: 2004
  end-page: 83
  ident: CR109
  article-title: Folate receptor targeted biodegradable polymeric doxorubicin micelles
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.02.003
– volume: 51
  start-page: 13
  issue: 1
  year: 1998
  end-page: 22
  ident: CR134
  article-title: Methoxy poly(ethylene glycol) and epsilon-caprolactone amphiphilic block copolymeric micelle containing indomethacin: II. Micelle formation and drug release behaviours
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(97)00124-7
– volume: 303
  start-page: 1818
  issue: 5665
  year: 2004
  end-page: 22
  ident: CR4
  article-title: Drag delivery systems: entering the mainstream
  publication-title: Science
  doi: 10.1126/science.1095833
– volume: 16
  start-page: 295
  issue: 2–3
  year: 1995
  end-page: 309
  ident: CR6
  article-title: Block copolymer micelles as long-circulating drag vehicles
  publication-title: Adv Drag Deliv Rev
  doi: 10.1016/0169-409X(95)00031-2
– volume: 18
  start-page: 623
  issue: 7
  year: 1997
  end-page: 33
  ident: CR68
  article-title: Pharmacokinetic and local tissue disposition studies of naproxen-following topical and systemic administration in dogs and rats
  publication-title: Biopharm Drug Dispos
  doi: 10.1002/(SICI)1099-081X(199710)18:7<623::AID-BDD46>3.0.CO;2-V
– volume: 294
  start-page: 247
  issue: 1–2
  year: 2005
  end-page: 59
  ident: CR35
  article-title: Investigation of lectin-modified insulin liposomes as carriers for oral administration
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2005.01.018
– volume: 93
  start-page: 678
  issue: 6
  year: 2005
  end-page: 87
  ident: CR91
  article-title: Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6602772
– volume: 66
  start-page: 11
  issue: 1
  year: 2007
  end-page: 20
  ident: CR40
  article-title: Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2006.09.002
– volume: 334
  start-page: 156
  issue: 1–2
  year: 2007
  end-page: 65
  ident: CR44
  article-title: Evaluation of bioadhesive potential and intestinal transport of pegylated poly(anhydride) nanoparticles
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.10.016
– volume: 28
  start-page: 101
  issue: 1
  year: 2002
  end-page: 5
  ident: CR79
  article-title: Ophthalmic vehicles containing polymer-solubilized tropicamide: ‘in vitro/in vivo’ evaluation
  publication-title: Drug Dev Ind Pharm
  doi: 10.1081/DDC-120001491
– volume: 76
  start-page: 1321
  issue: 7–8
  year: 2004
  end-page: 35
  ident: CR28
  article-title: Polymeric micelles for oral drag delivery: why and how
  publication-title: Pure Appl Chem
  doi: 10.1351/pac200476071321
– volume: 29
  start-page: 928
  issue: 10
  year: 2006
  end-page: 33
  ident: CR66
  article-title: Enhanced transdermal delivery of pranoprofen from the bioadhesive gels
  publication-title: Arch Pharm Res
  doi: 10.1007/BF02973916
– volume: 88
  start-page: 11460
  issue: 24
  year: 1991
  end-page: 4
  ident: CR124
  article-title: Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.88.24.11460
– volume: 13
  start-page: 391
  issue: 7
  year: 2005
  end-page: 7
  ident: CR110
  article-title: Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice
  publication-title: J Drug Target
  doi: 10.1080/10611860500376741
– volume: 47
  start-page: 555
  issue: 6
  year: 2003
  end-page: 62
  ident: CR63
  article-title: Poloxamer gel as vehicle for transdermal iontophoretic delivery of arginine vasopressin: evaluation of in vivo performance in rats
  publication-title: Pharmacol Res
  doi: 10.1016/S1043-6618(03)00043-4
– volume: 92
  start-page: 1343
  issue: 7
  year: 2003
  end-page: 55
  ident: CR10
  article-title: Amphiphilic block copolymers for drag delivery
  publication-title: J Pharm Sci
  doi: 10.1002/jps.10397
– year: 2005
  ident: CR29
  publication-title: Polymeric drag delivery systems: drags and the pharmaceutical sciences
– volume: 111
  start-page: 47
  issue: 1–2
  year: 2006
  end-page: 55
  ident: CR52
  article-title: Intestinal uptake and biodistribution of novel polymeric micelles after oral administration
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2005.11.012
– volume: 9
  start-page: 956
  issue: 11
  year: 2007
  end-page: 66
  ident: CR33
  article-title: Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters
  publication-title: J Gene Med
  doi: 10.1002/jgm.1093
– volume: 15
  start-page: 441
  issue: 3
  year: 2004
  end-page: 8
  ident: CR137
  article-title: Core-cross-linked polymeric micelles as paclitaxel carriers
  publication-title: Bioconjug Chem
  doi: 10.1021/bc034113u
– volume: 16
  start-page: 396
  issue: 3
  year: 1999
  end-page: 401
  ident: CR148
  article-title: Inhibition of multidrug resistance-associated protein (MRP) functional activity with Pluronic block copolymers
  publication-title: Pharm Res
  doi: 10.1023/A:1018873702411
– volume: 15
  start-page: 215
  issue: 7
  year: 1994
  end-page: 20
  ident: CR3
  article-title: Long-circulating (sterically stabilized) liposomes for targeted drag delivery
  publication-title: Trends Pharmacol Sci
  doi: 10.1016/0165-6147(94)90314-X
– volume: 117
  start-page: 59
  issue: 1
  year: 2007
  end-page: 67
  ident: CR54
  article-title: A mixed polymeric micellar formulation of itraconazole: characteristics, toxicity and pharmacokinetics
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2006.10.001
– volume: 74
  start-page: 295
  issue: 1–3
  year: 2001
  end-page: 302
  ident: CR106
  article-title: Development of the polymer micelle carrier system for doxorubicin
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00341-8
– volume: 21
  start-page: 1184
  issue: 7
  year: 2004
  end-page: 91
  ident: CR133
  article-title: Preparation and drug loading of poly(ethylene glycol)-block-poly(epsilon-caprolactone) micelles through the evaporation of a cosolvent azeotrope
  publication-title: Pharm Res
  doi: 10.1023/B:PHAM.0000033005.25698.9c
– volume: 16
  start-page: 3
  issue: 1–4
  year: 1999
  end-page: 27
  ident: CR12
  article-title: Nano-engineering block copolymer aggregates for drag delivery
  publication-title: Colloids Surf B Biointerfaces
  doi: 10.1016/S0927-7765(99)00058-2
– volume: 65
  start-page: 309
  issue: 3
  year: 2007
  end-page: 19
  ident: CR97
  article-title: In vivo fate of unimers and micelles of a poly(ethylene glycol)-block-poly(caprolactone) copolymer in mice following intravenous administration
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2006.11.010
– volume: 40
  start-page: 81
  issue: 1
  year: 1997
  end-page: 6
  ident: CR112
  article-title: An investigation of the antitumour activity and biodistribution of polymeric micellar paclitaxel
  publication-title: Cancer Chemother Pharmacol
  doi: 10.1007/s002800050630
– volume: 19
  start-page: 418
  issue: 4
  year: 2002
  end-page: 22
  ident: CR132
  article-title: Block copolymer micelles for the encapsulation and delivery of amphotericin B
  publication-title: Pharm Res
  doi: 10.1023/A:1015127225021
– volume: 100
  start-page: 389
  issue: 3
  year: 2004
  end-page: 97
  ident: CR96
  article-title: Distribution kinetics of a micelle-forming block copolymer Pluronic P85
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.09.002
– volume: 6
  start-page: 2462
  issue: 5
  year: 2005
  end-page: 7
  ident: CR27
  article-title: Exploiting the vitamin B12 pathway to enhance oral drug delivery via polymeric micelles
  publication-title: Biomacromolecules
  doi: 10.1021/bm0503165
– volume: 122
  start-page: 63
  issue: 1
  year: 2007
  end-page: 70
  ident: CR82
  article-title: A novel use of an in vitro method to predict the in vivo stability of block copolymer based nano-containers
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2007.06.008
– volume: 54
  start-page: 169
  issue: 2
  year: 2002
  end-page: 90
  ident: CR17
  article-title: Poly(ethylene oxide)-block-poly(L-amino acid) micelles for drag delivery
  publication-title: Adv Drag Deliv Rev
  doi: 10.1016/S0169-409X(02)00015-7
– volume: 63
  start-page: 8977
  issue: 24
  year: 2003
  end-page: 83
  ident: CR118
  article-title: Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice
  publication-title: Cancer Res
– volume: 94
  start-page: 323
  issue: 2–3
  year: 2004
  end-page: 35
  ident: CR131
  article-title: Incorporation and release behavior of hydrophobic drug in functionalized poly(D,L-lactide)-block-poly(ethylene oxide) micelles
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2003.10.012
– volume: 193
  start-page: 213
  issue: 2
  year: 2000
  end-page: 8
  ident: CR32
  article-title: Enhanced efficacy by percutaneous absorption of piroxicam from the poloxamer gel in rats
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(99)00339-7
– volume: 48
  start-page: 101
  issue: 2
  year: 1999
  end-page: 11
  ident: CR20
  article-title: Polymeric micelles: a new generation of colloidal drug carriers
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/S0939-6411(99)00039-9
– volume: 18
  start-page: 1035
  issue: 7
  year: 2001
  end-page: 41
  ident: CR90
  article-title: Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system
  publication-title: Pharm Res
  doi: 10.1023/A:1010908916184
– volume: 20
  start-page: 1085
  issue: 7
  year: 2003
  end-page: 92
  ident: CR48
  article-title: The effects of Pluronics block copolymers and Cremophor EL on intestinal lipoprotein processing and the potential link with P-glycoprotein in Caco-2 cells
  publication-title: Pharm Res
  doi: 10.1023/A:1024422625596
– volume: 15
  start-page: 1525
  issue: 10
  year: 1998
  end-page: 32
  ident: CR46
  article-title: Effects of Pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells
  publication-title: Pharm Res
  doi: 10.1023/A:1011942814300
– volume: 16
  start-page: 113
  issue: 1–4
  year: 1999
  end-page: 34
  ident: CR85
  article-title: Block copolymer-based formulation of doxorubicin: from cell screen to clinical trials
  publication-title: Colloids Surf B Biointerfaces
  doi: 10.1016/S0927-7765(99)00064-8
– volume: 343
  start-page: 34
  issue: 1–2
  year: 2007
  end-page: 40
  ident: CR75
  article-title: Gels and liposomes in optimized ocular drug delivery: studies on ciprofloxacin formulations
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2007.04.013
– volume: 8
  start-page: 999
  issue: 13
  year: 2001
  end-page: 1004
  ident: CR78
  article-title: In vivo gene delivery into ocular tissues by eye drops of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) polymeric micelles
  publication-title: Gene Ther
  doi: 10.1038/sj.gt.3301485
– volume: 15
  start-page: 481
  issue: 5
  year: 2004
  end-page: 93
  ident: CR24
  article-title: Nonionic polymeric micelles for oral gene delivery in vivo
  publication-title: Hum Gene Ther
  doi: 10.1089/10430340460745801
– volume: 116
  start-page: e53
  issue: 2
  year: 2006
  end-page: 5
  ident: CR67
  article-title: Transdermal timolol delivery from a Pluronic gel
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2006.09.046
– volume: 73
  start-page: 137
  issue: 2–3
  year: 2001
  end-page: 72
  ident: CR23
  article-title: Structure and design of polymeric surfactant-based drug delivery systems
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00299-1
– volume: 44
  start-page: 156
  issue: 2
  year: 2000
  end-page: 63
  ident: CR114
  article-title: Polymeric micellar paclitaxel phosphorylates Bcl-2 and induces apoptotic regression of androgen-independent LNCaP prostate tumors
  publication-title: Prostate
  doi: 10.1002/1097-0045(20000701)44:2<156::AID-PROS8>3.0.CO;2-8
– volume: 1066
  start-page: 159
  issue: 2
  year: 1991
  end-page: 65
  ident: CR126
  article-title: Large liposomes containing ganglioside GM1 accumulate effectively in spleen
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(91)90182-8
– volume: 108
  start-page: 241
  issue: 2
  year: 2008
  end-page: 50
  ident: CR143
  article-title: Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer
  publication-title: Breast Cancer Res Treat
  doi: 10.1007/s10549-007-9591-y
– volume: 90
  start-page: 2085
  issue: 11
  year: 2004
  end-page: 91
  ident: CR86
  article-title: Phase I dose escalation and pharmacokinetic study of Pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer
  publication-title: Br J Cancer
– volume: 29
  start-page: 17
  year: 1994
  end-page: 23
  ident: CR104
  article-title: Enhanced tumor accumulation and prolonged circulation times for micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(94)90118-X
– volume: 95
  start-page: 601
  issue: 5
  year: 2006
  end-page: 6
  ident: CR153
  article-title: NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6603311
– volume: 304
  start-page: 845
  issue: 2
  year: 2003
  end-page: 54
  ident: CR150
  article-title: Optimal structure requirements for Pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.102.043307
– volume: 1066
  start-page: 29
  issue: 1
  year: 1991
  end-page: 36
  ident: CR92
  article-title: Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(91)90246-5
– volume: 42
  start-page: 419
  issue: 5
  year: 2003
  end-page: 36
  ident: CR93
  article-title: Pharmacokinetics of pegylated liposomal doxorubicin: review of animal and human studies
  publication-title: Clin Pharmacokinet
  doi: 10.2165/00003088-200342050-00002
– volume: 43
  start-page: 489
  issue: 6
  year: 2004
  end-page: 533
  ident: CR73
  article-title: Oil-in-water lipid emulsions: implications for parenteral and ocular delivering systems
  publication-title: Prog Lipid Res
  doi: 10.1016/j.plipres.2004.09.001
– volume: 92
  start-page: 1240
  issue: 7
  year: 2005
  end-page: 6
  ident: CR88
  article-title: NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6602479
– volume: 118
  start-page: 105
  issue: 1
  year: 2007
  end-page: 17
  ident: CR25
  article-title: Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2006.12.007
– volume: 26
  start-page: 7251
  issue: 35
  year: 2005
  end-page: 9
  ident: CR83
  article-title: Polymeric micelles for the solublization and delivery of cyclosporine A: pharmacokinetics and biodistribution
  publication-title: Bio-materials
– volume: 54
  start-page: 235
  issue: 2
  year: 2002
  end-page: 52
  ident: CR22
  article-title: PEG-based micelles as carriers of contrast agents for different imaging modalities
  publication-title: Adv Drag Deliv Rev
  doi: 10.1016/S0169-409X(02)00019-4
– volume: 4
  start-page: E40
  issue: 4
  year: 2002
  ident: CR57
  article-title: An in vitro examination of the impact of polyethylene glycol 400, Pluronic P85, and vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine
  publication-title: AAPS Pharm Sci
  doi: 10.1208/ps040440
– volume: 58
  start-page: 903
  issue: 7
  year: 2006
  end-page: 8
  ident: CR65
  article-title: In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a Pluronic lecithin organogel vehicle containing fish oil
  publication-title: J Pharm Pharmacol
  doi: 10.1211/jpp.58.7.0004
– volume: 66
  start-page: 10048
  issue: 20
  year: 2006
  end-page: 56
  ident: CR122
  article-title: Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-06-1605
– volume: 33
  start-page: 1142
  issue: 10
  year: 2007
  end-page: 50
  ident: CR80
  article-title: Ocular permeability of pirenzepine hydrochloride enhanced by methoxy poly(ethylene glycol)-poly(D,L-lactide) block copolymer
  publication-title: Drug Del Ind Pharm
  doi: 10.1080/03639040701397381
– volume: 53
  start-page: 466
  issue: 7
  year: 1998
  end-page: 9
  ident: CR74
  article-title: Discoidal niosome based controlled ocular delivery of timolol maleate
  publication-title: Pharmazie
– volume: 22
  start-page: 2049
  issue: 14
  year: 2001
  end-page: 56
  ident: CR123
  article-title: Indomethacin-loaded methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) diblock copolymeric nanosphere: pharmacokinetic characteristics of indomethacin in the normal Sprague-Dawley rats
  publication-title: Biomaterials
  doi: 10.1016/S0142-9612(00)00393-8
– volume: 229
  start-page: 29
  issue: 1–2
  year: 2001
  end-page: 36
  ident: CR70
  article-title: In situ gelling xyloglucan formulations for sustained release ocular delivery of pilocarpine hydrochloride
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(01)00825-0
– volume: 54
  start-page: 8
  issue: 4
  year: 1997
  end-page: 14
  ident: CR2
  article-title: Liposomes: opportunities in drag delivery
  publication-title: Drags
  doi: 10.2165/00003495-199700544-00004
– volume: 74
  start-page: 1545
  issue: 10
  year: 1996
  end-page: 52
  ident: CR145
  article-title: Anthracycline antibiotics non-covalently incorporated into the block copolymer micelles: in vivo evaluation of anti-cancer activity
  publication-title: Br J Cancer
  doi: 10.1038/bjc.1996.587
– volume: 20
  start-page: 357
  issue: 5
  year: 2003
  end-page: 403
  ident: CR16
  article-title: Polymeric micelles for delivery of poorly water-soluble compounds
  publication-title: Crit Rev Ther Drug Carrier Syst
  doi: 10.1615/CritRevTherDrugCarrierSyst.v20.i5.20
– volume: 51
  start-page: 3229
  issue: 12
  year: 1991
  end-page: 36
  ident: CR103
  article-title: Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood
  publication-title: Cancer Res
– volume: 8
  start-page: 202
  issue: 1
  year: 2007
  end-page: 8
  ident: CR53
  article-title: Hydrotropic polymeric micelles for enhanced paclitaxel solubility: in vitro and in vivo characterization
  publication-title: Biomacromolecules
  doi: 10.1021/bm060307b
– volume: 50
  start-page: 1693
  issue: 6
  year: 1990
  end-page: 700
  ident: CR139
  article-title: Characterization and anticancer activity of the micelle-forming polymeric anticancer drug Adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
  publication-title: Cancer Res
– volume: 16
  start-page: 1373
  issue: 9
  year: 1999
  end-page: 9
  ident: CR149
  article-title: Fundamental relationships between the composition of Pluronic block copolymers and their hypersensitization effect in MDR cancer cells
  publication-title: Pharm Res
  doi: 10.1023/A:1018942823676
– volume: 2
  start-page: 15
  issue: 1
  year: 2004
  end-page: 42
  ident: CR18
  article-title: Micelles in anticancer drag delivery
  publication-title: Am J Drug Del
  doi: 10.2165/00137696-200402010-00002
– volume: 283
  start-page: 954
  issue: 9
  year: 2005
  end-page: 67
  ident: CR121
  article-title: Stealth MePEG-PCL micelles: effects of polymer composition on micelles physiochemical characteristics, in vitro drug release, in vivo pharmacokinetics in rats and biodistribution in S180 tumor bearing mice
  publication-title: Colloid Polym Sci
  doi: 10.1007/s00396-004-1243-8
– volume: 54
  start-page: 299
  issue: 3
  year: 2002
  end-page: 309
  ident: CR50
  article-title: Enhanced cellular accumulation of a P-glycoprotein substrate, rhodamine-123, by Caco-2 cells using low molecular weight methoxypolyethylene glycol-block-polycaprolactone diblock copolymers
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/S0939-6411(02)00119-4
– volume: 61
  start-page: 2541
  issue: 23
  year: 2004
  end-page: 4
  ident: CR61
  article-title: Relative bioavailability of ketoprofen 20% in a poloxamer-lecithin organogel
  publication-title: Am J Health Syst Pharm
– volume: 8
  start-page: 696
  issue: 7
  year: 1997
  end-page: 701
  ident: CR113
  article-title: Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel
  publication-title: Anticancer Drugs
  doi: 10.1097/00001813-199708000-00008
– volume: 77
  start-page: 155
  issue: 1–2
  year: 2001
  end-page: 60
  ident: CR135
  article-title: Micelles self-assembled from poly(ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: effect on the solubilization and haemolytic activity of amphotericin B
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00477-1
– volume: 47
  start-page: 113
  issue: 1
  year: 2001
  end-page: 31
  ident: CR5
  article-title: Block copolymer micelles for drag delivery: design, characterization and biological significance
  publication-title: Adv Drag Deliv Rev
  doi: 10.1016/S0169-409X(00)00124-1
– volume: 9
  start-page: 139
  issue: 1
  year: 1999
  end-page: 51
  ident: CR11
  article-title: Copolymer drag carriers: conjugates, micelles and microspheres
  publication-title: STP Pharma Sci
– volume: 98
  start-page: 415
  issue: 3
  year: 2004
  end-page: 26
  ident: CR136
  article-title: Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.06.003
– volume: 7
  start-page: 144
  issue: 1
  year: 1996
  end-page: 9
  ident: CR120
  article-title: An adduct of cis-diam-minedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties
  publication-title: Bioconjug Chem
  doi: 10.1021/bc950089b
– volume: 15
  start-page: 481
  issue: 5
  year: 1998
  end-page: 512
  ident: CR15
  article-title: Diblock copolymer nanoparticles for drag delivery
  publication-title: Crit Rev Ther Drag Carrier Syst
– volume: 981
  start-page: 27
  issue: 1
  year: 1989
  end-page: 35
  ident: CR125
  article-title: Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(89)90078-3
– volume: 332
  start-page: 161
  issue: 1–2
  year: 2007
  end-page: 7
  ident: CR43
  article-title: Investigation of Pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.09.030
– volume: 56
  start-page: 3626
  issue: 16
  year: 1996
  end-page: 9
  ident: CR146
  article-title: Hypersensitizing effect of Pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells
  publication-title: Cancer Res
– volume: 11
  start-page: 269
  issue: 1–3
  year: 1990
  end-page: 78
  ident: CR101
  article-title: Polymer micelles as novel drug carrier: Adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
  publication-title: J Control Rel
– volume: 10
  start-page: 3708
  issue: 11
  year: 2004
  end-page: 16
  ident: CR115
  article-title: Phase I and pharmacokinetic study of Genexol-PM, a Cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-03-0655
– volume: 8
  start-page: 1
  issue: 1
  year: 2007
  ident: CR76
  article-title: Liposomes as an ocular delivery system for acetazolamide: in vitro and in vivo studies
  publication-title: AAPS Pharm Sci Tech
  doi: 10.1208/pt0801001
– volume: 64
  start-page: 143
  issue: 1–3
  year: 2000
  end-page: 53
  ident: CR108
  article-title: Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(99)00133-9
– volume: 9
  start-page: 213
  issue: 3–4
  year: 1992
  end-page: 48
  ident: CR9
  article-title: Block copolymers as drag carriers
  publication-title: Crit Rev Ther Drag Carrier Syst
– volume: 202
  start-page: 161
  issue: 1–2
  year: 2000
  end-page: 4
  ident: CR72
  article-title: Increased partitioning of pilocarpine to the oily phase of submicron emulsion does not result in improved ocular bioavailability
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(00)00443-9
– volume: 18
  start-page: 2009
  issue: 12
  year: 2007
  end-page: 14
  ident: CR142
  article-title: Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cis-platin in patients with advanced non-small-cell lung cancer
  publication-title: Ann Oncol
  doi: 10.1093/annonc/mdm374
– volume: 209
  start-page: 1
  issue: 1–2
  year: 2000
  end-page: 14
  ident: CR77
  article-title: Ketorolac entrapped in polymeric micelles: preparation, characterisation and ocular anti-inflammatory studies
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(00)00508-1
– volume: 31
  start-page: 447
  issue: 4–5
  year: 2005
  end-page: 54
  ident: CR62
  article-title: In vivo skin permeation of sodium naproxen formulated in Pluronic F-127 gels: effect of Azone and Transcutol
  publication-title: Drug Dev Ind Pharm
  doi: 10.1080/03639040500214662
– volume: 22
  start-page: 362S
  issue: 14S
  year: 2004
  ident: CR151
  article-title: A phase II, window study of SP1049C as first-line therapy in inoperable metastatic adenocarcinoma of the oesophagus [abstract no. 4195]
  publication-title: J Clin Oncol
– volume: 21
  start-page: 107
  issue: 2
  year: 1996
  end-page: 16
  ident: CR7
  article-title: Polymeric micelles as new drug carriers
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(96)00401-2
– volume: 298
  start-page: 176
  issue: 1
  year: 2005
  end-page: 85
  ident: CR36
  article-title: A lecithin-based microemulsion of rh-insulin with aprotinin for oral administration: investigation of hypoglycemic effects in non-diabetic and STZ-induced diabetic rats
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2005.04.016
– volume: 101
  start-page: 223
  issue: 1–3
  year: 2005
  end-page: 32
  ident: CR119
  article-title: Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.08.022
– volume: 91
  start-page: 1775
  issue: 10
  year: 2004
  end-page: 81
  ident: CR89
  article-title: Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6602204
– volume: 15
  start-page: 850
  issue: 6
  year: 1998
  end-page: 5
  ident: CR147
  article-title: Effects of Pluronic block copolymers on drug absorption in Caco-2 cell monolayers
  publication-title: Pharm Res
  doi: 10.1023/A:1011964213024
– volume: 325
  start-page: 155
  issue: 1–2
  year: 2006
  end-page: 62
  ident: CR34
  article-title: Novel O-palmitoylscleroglucan-coated liposomes as drag carriers: development, characterization and interaction with leuprolide
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.06.040
– volume: 30
  start-page: 1138
  issue: 9
  year: 2007
  end-page: 43
  ident: CR30
  article-title: Pharmaceutical evaluation of genistein-loaded Pluronic micelles for oral delivery
  publication-title: Arch Pharm Res
  doi: 10.1007/BF02980249
– volume: 27
  start-page: 5855
  issue: 34
  year: 2006
  end-page: 60
  ident: CR47
  article-title: In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2006.08.004
– volume: 42
  start-page: 463
  issue: 6
  year: 2003
  end-page: 78
  ident: CR95
  article-title: Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties
  publication-title: Prog Lipid Res
  doi: 10.1016/S0163-7827(03)00033-X
– volume: 12
  start-page: 517
  issue: 8
  year: 2004
  end-page: 26
  ident: CR49
  article-title: Mixed polymer micelles of amphiphilic and cationic copolymers for delivery of antisense oligonucleotides
  publication-title: J Drug Target
  doi: 10.1080/10611860400011927
– volume: 51
  start-page: 169
  issue: 2–3
  year: 1998
  end-page: 78
  ident: CR129
  article-title: Clonazepam release from core-shell type nanoparticles in vitro
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(97)00163-6
– volume: 3
  start-page: 139
  issue: 1
  year: 2006
  end-page: 62
  ident: CR1
  article-title: Polymeric micelles for drag delivery
  publication-title: Expert Opin Drag Del
  doi: 10.1517/17425247.3.1.139
– volume: 15
  start-page: 553
  issue: 9
  year: 2007
  end-page: 84
  ident: CR19
  article-title: Polymeric micelles for drag targeting
  publication-title: J Drag Target
  doi: 10.1080/10611860701538586
– volume: 64
  start-page: 1733
  issue: 19
  year: 1999
  end-page: 8
  ident: CR59
  article-title: Significantly improved oral uptake of amikacin in FVB mice in the presence of CRL-1605 copolymer
  publication-title: Life Sci
  doi: 10.1016/S0024-3205(99)00111-3
– volume: 66
  start-page: 303
  issue: 3
  year: 2007
  end-page: 17
  ident: CR26
  article-title: Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drag delivery agents: improved hydrosolubility, stability and bioavailability of drugs
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2007.03.022
– volume: 21
  start-page: 418
  issue: 4
  year: 1998
  end-page: 22
  ident: CR130
  article-title: Clonazepam release from poly(DL-lactide-co-glycolide) nanoparticles prepared by dialysis method
  publication-title: Arch Pharm Res
  doi: 10.1007/BF02974636
– volume: 54
  start-page: 37
  issue: 1
  year: 2002
  end-page: 51
  ident: CR60
  article-title: Thermosensitive sol-gel reversible hydrogels
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(01)00242-3
– volume: 10
  start-page: 970
  issue: 7
  year: 1993
  end-page: 4
  ident: CR102
  article-title: Biodistribution of micelle-forming polymer-drug conjugates
  publication-title: Pharm Res
  doi: 10.1023/A:1018998203127
– volume: 102
  start-page: 657
  issue: 3
  year: 2005
  end-page: 68
  ident: CR51
  article-title: Self-assembling PEG-p(CL-co-TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.10.022
– volume: 6
  start-page: 639
  issue: 6
  year: 1995
  end-page: 43
  ident: CR13
  article-title: Water-soluble block polycations as carriers for oligonucleotide delivery
  publication-title: Bioconjug Chem
  doi: 10.1021/bc00036a001
– volume: 7
  start-page: 171
  issue: 3
  year: 1999
  end-page: 86
  ident: CR105
  article-title: Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system
  publication-title: J Drug Target
  doi: 10.3109/10611869909085500
– volume: 97
  start-page: 170
  issue: 2
  year: 2007
  end-page: 6
  ident: CR87
  article-title: A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6603855
– volume: 72
  start-page: 191
  issue: 1–3
  year: 2001
  end-page: 202
  ident: CR99
  article-title: In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00275-9
– volume: 42
  start-page: 943
  issue: 1–9
  year: 2004
  end-page: 50
  ident: CR107
  article-title: Ultrasound-triggered drug targeting of tumors in vitro and in vivo
  publication-title: Ultrasonics
  doi: 10.1016/j.ultras.2004.01.087
– volume: 61
  start-page: 2549
  issue: 19–20
  year: 2004
  end-page: 59
  ident: CR8
  article-title: Targeted polymeric micelles for delivery of poorly soluble drags
  publication-title: Cell Mol Life Sci
  doi: 10.1007/s00018-004-4153-5
– volume: 32
  start-page: 269
  year: 1994
  end-page: 77
  ident: CR140
  article-title: Improved synthesis of adriamycin-conjugated poly(ethylene oxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped adriamycin
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(94)90237-2
– volume: 126
  start-page: 10640
  issue: 34
  year: 2004
  end-page: 4
  ident: CR69
  article-title: Supramolecular assemblies based on copolymers of PEG600 and functionalized aromatic diesters for drug delivery applications
  publication-title: J Am Chem Soc
  doi: 10.1021/ja039651w
– volume: 27
  start-page: 747
  issue: 6
  year: 2006
  end-page: 53
  ident: CR116
  article-title: Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123
  publication-title: Acta Pharmacol Sin
  doi: 10.1111/j.1745-7254.2006.00340.x
– volume: 20
  start-page: 24
  issue: 1
  year: 2003
  end-page: 30
  ident: CR55
  article-title: Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031
  publication-title: Pharm Res
  doi: 10.1023/A:1022286422439
– volume: 7
  start-page: 1259
  issue: 9
  year: 2007
  end-page: 64
  ident: CR38
  article-title: The immune response and protective efficacy of vaccination with oral microparticle vaccine in mice
  publication-title: Int Immunopharmacol
  doi: 10.1016/j.intimp.2007.05.003
– volume: 92
  start-page: 328
  issue: 3
  year: 2001
  end-page: 36
  ident: CR117
  article-title: Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity
  publication-title: Jpn J Cancer Res
  doi: 10.1111/j.1349-7006.2001.tb01099.x
– volume: 104
  start-page: 289
  issue: 2
  year: 2005
  end-page: 300
  ident: CR31
  article-title: Enhancement of oral bioavailability of poorly water-soluble drugs by poly(ethylene glycol)-block-poly(alkyl acrylate-co-methacrylic acid) self-assemblies
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2005.02.010
– volume: 5
  start-page: 521
  issue: 4
  year: 2000
  end-page: 32
  ident: CR71
  article-title: Influence of emulsion droplet surface charge on indomethacin ocular tissue distribution
  publication-title: Pharm Dev Technol
  doi: 10.1081/PDT-100102035
– volume: 2
  start-page: 35
  issue: 1
  year: 2005
  end-page: 44
  ident: CR98
  article-title: In vivo pharmacokinetic and tissue distribution studies in mice of alternative formulations for local and systemic delivery of paclitaxel: gel, film, prodrug, liposomes and micelles
  publication-title: Curr Drug Deliv
  doi: 10.2174/1567201052772852
– volume: 103
  start-page: 405
  issue: 2
  year: 2005
  end-page: 18
  ident: CR111
  article-title: Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.12.018
– volume: 132
  start-page: 195
  issue: 1–2
  year: 1996
  end-page: 206
  ident: CR152
  article-title: Development of amphiphilic diblock copolymers as micellar carriers of Taxol
  publication-title: Int J Pharm
  doi: 10.1016/0378-5173(95)04386-1
– ident: CR141
– volume: 333
  start-page: 87
  issue: 1–2
  year: 2007
  end-page: 94
  ident: CR41
  article-title: Sustained-release tablets of indomethacin-loaded microcapsules: preparation, in vitro and in vivo characterization
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.10.002
– volume: 67
  start-page: 2011
  issue: 16
  year: 2000
  ident: R58-1-20080912
  publication-title: Life Sci
  doi: 10.1016/S0024-3205(00)00786-4
– volume: 73
  start-page: 137
  issue: 2-3
  year: 2001
  ident: R23-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00299-1
– volume: 64
  start-page: 1733
  issue: 19
  year: 1999
  ident: R59-1-20080912
  publication-title: Life Sci
  doi: 10.1016/S0024-3205(99)00111-3
– volume: 9
  start-page: 956
  issue: 11
  year: 2007
  ident: R33-1-20080912
  publication-title: J Gene Med
  doi: 10.1002/jgm.1093
– volume: 15
  start-page: 553
  issue: 9
  year: 2007
  ident: R19-1-20080912
  publication-title: J Drug Target
  doi: 10.1080/10611860701538586
– volume: 7
  start-page: 209
  issue: 2
  year: 1996
  ident: R144-1-20080912
  publication-title: Bioconjug Chem
  doi: 10.1021/bc950093n
– volume: 42
  start-page: 463
  issue: 6
  year: 2003
  ident: R95-1-20080912
  publication-title: Prog Lipid Res
  doi: 10.1016/S0163-7827(03)00033-X
– volume: 47
  start-page: 113
  issue: 1
  year: 2001
  ident: R5-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(00)00124-1
– volume: 15
  start-page: 1525
  issue: 10
  year: 1998
  ident: R46-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1011942814300
– volume: 50
  start-page: 1693
  issue: 6
  year: 1990
  ident: R139-1-20080912
  publication-title: Cancer Res
– volume: 193
  start-page: 67
  year: 2006
  ident: R84-1-20080912
  publication-title: Adv Polym Sci
  doi: 10.1007/12_025
– volume: 27
  start-page: 5855
  issue: 34
  year: 2006
  ident: R47-1-20080912
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2006.08.004
– volume: 20
  start-page: 24
  issue: 1
  year: 2003
  ident: R55-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1022286422439
– volume: 229
  start-page: 29
  issue: 1-2
  year: 2001
  ident: R70-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(01)00825-0
– volume: 116
  start-page: e53
  issue: 2
  year: 2006
  ident: R67-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2006.09.046
– volume: 66
  start-page: 303
  issue: 3
  year: 2007
  ident: R26-1-20080912
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2007.03.022
– volume: 44
  start-page: 156
  issue: 2
  year: 2000
  ident: R114-1-20080912
  publication-title: Prostate
  doi: 10.1002/1097-0045(20000701)44:2<156::AID-PROS8>3.0.CO;2-8
– volume: 48
  start-page: 101
  issue: 2
  year: 1999
  ident: R20-1-20080912
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/S0939-6411(99)00039-9
– volume: 10
  start-page: 970
  issue: 7
  year: 1993
  ident: R102-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1018998203127
– volume: 6
  start-page: 639
  issue: 6
  year: 1995
  ident: R13-1-20080912
  publication-title: Bioconjug Chem
  doi: 10.1021/bc00036a001
– volume: 193
  start-page: 213
  issue: 2
  year: 2000
  ident: R32-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(99)00339-7
– volume: 20
  start-page: 1085
  issue: 7
  year: 2003
  ident: R48-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1024422625596
– volume: 103
  start-page: 405
  issue: 2
  year: 2005
  ident: R111-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.12.018
– volume: 108
  start-page: 241
  issue: 2
  year: 2008
  ident: R143-1-20080912
  publication-title: Breast Cancer Res Treat
  doi: 10.1007/s10549-007-9591-y
– volume: 51
  start-page: 3229
  issue: 12
  year: 1991
  ident: R103-1-20080912
  publication-title: Cancer Res
– volume: 19
  start-page: 418
  issue: 4
  year: 2002
  ident: R132-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1015127225021
– volume: 334
  start-page: 156
  issue: 1-2
  year: 2007
  ident: R44-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.10.016
– volume: 8
  start-page: 202
  issue: 1
  year: 2007
  ident: R53-1-20080912
  publication-title: Biomacromolecules
  doi: 10.1021/bm060307b
– volume: 304
  start-page: 845
  issue: 2
  year: 2003
  ident: R150-1-20080912
  publication-title: J Pharmacol Exp Ther
  doi: 10.1124/jpet.102.043307
– volume: 16
  start-page: 396
  issue: 3
  year: 1999
  ident: R148-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1018873702411
– volume: 104
  start-page: 289
  issue: 2
  year: 2005
  ident: R31-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2005.02.010
– volume: 33
  start-page: 1142
  issue: 10
  year: 2007
  ident: R80-1-20080912
  publication-title: Drug Del Ind Pharm
  doi: 10.1080/03639040701397381
– volume: 93
  start-page: 678
  issue: 6
  year: 2005
  ident: R91-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6602772
– volume: 119
  start-page: 299
  issue: 3-4
  year: 2007
  ident: R39-1-20080912
  publication-title: Vet Immunol and Immunopathol
  doi: 10.1016/j.vetimm.2007.05.011
– volume: 66
  start-page: 11
  issue: 1
  year: 2007
  ident: R40-1-20080912
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2006.09.002
– volume: 2
  start-page: 15
  issue: 1
  year: 2004
  ident: R18-1-20080912
  publication-title: Am J Drug Del
  doi: 10.2165/00137696-200402010-00002
– volume: 122
  start-page: 63
  issue: 1
  year: 2007
  ident: R82-1-20080912
  publication-title: JControl Rel
  doi: 10.1016/j.jconrel.2007.06.008
– volume: 100
  start-page: 389
  issue: 3
  year: 2004
  ident: R96-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.09.002
– volume: 63
  start-page: 8977
  issue: 24
  year: 2003
  ident: R118-1-20080912
  publication-title: Cancer Res
– volume: 54
  start-page: 37
  issue: 1
  year: 2002
  ident: R60-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(01)00242-3
– volume: 18
  start-page: 1035
  issue: 7
  year: 2001
  ident: R90-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1010908916184
– volume: 1066
  start-page: 29
  issue: 1
  year: 1991
  ident: R92-1-20080912
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(91)90246-5
– volume: 21
  start-page: 107
  issue: 2
  year: 1996
  ident: R7-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(96)00401-2
– volume: 61
  start-page: 2549
  issue: 19-20
  year: 2004
  ident: R8-1-20080912
  publication-title: Cell Mol Life Sci
  doi: 10.1007/s00018-004-4153-5
– volume: 58
  start-page: 903
  issue: 7
  year: 2006
  ident: R65-1-20080912
  publication-title: J Pharm Pharmacol
  doi: 10.1211/jpp.58.7.0004
– volume: 15
  start-page: 481
  issue: 5
  year: 1998
  ident: R15-1-20080912
  publication-title: Crit Rev Ther Drug Carrier Syst
  doi: 10.1615/CritRevTherDrugCarrierSyst.v15.i5.20
– volume: 16
  start-page: 267
  issue: 2-3
  year: 1995
  ident: R81-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/0169-409X(95)00029-7
– volume: 20
  start-page: 357
  issue: 5
  year: 2003
  ident: R16-1-20080912
  publication-title: Crit Rev Ther Drug Carrier Syst
  doi: 10.1615/CritRevTherDrugCarrierSyst.v20.i5.20
– volume: 283
  start-page: 954
  issue: 9
  year: 2005
  ident: R121-1-20080912
  publication-title: Colloid Polym Sci
  doi: 10.1007/s00396-004-1243-8
– volume: 332
  start-page: 161
  issue: 1-2
  year: 2007
  ident: R43-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.09.030
– volume: 40
  start-page: 539
  issue: 7
  year: 2001
  ident: R94-1-20080912
  publication-title: Clin Pharmacokinet
  doi: 10.2165/00003088-200140070-00005
– volume: 9
  start-page: 213
  issue: 3-4
  year: 1992
  ident: R9-1-20080912
  publication-title: Crit Rev Ther Drug Carrier Syst
– volume: 8
  start-page: 696
  issue: 7
  year: 1997
  ident: R113-1-20080912
  publication-title: Anticancer Drugs
  doi: 10.1097/00001813-199708000-00008
– volume: 28
  start-page: 101
  issue: 1
  year: 2002
  ident: R79-1-20080912
  publication-title: Drug Dev Ind Pharm
  doi: 10.1081/DDC-120001491
– volume: 76
  start-page: 1321
  issue: 7-8
  year: 2004
  ident: R28-1-20080912
  publication-title: Pure Appl Chem
  doi: 10.1351/pac200476071321
– volume: 117
  start-page: 59
  issue: 1
  year: 2007
  ident: R54-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2006.10.001
– volume: 27
  start-page: 747
  issue: 6
  year: 2006
  ident: R116-1-20080912
  publication-title: Acta Pharmacol Sin
  doi: 10.1111/j.1745-7254.2006.00340.x
– volume: 16
  start-page: 295
  issue: 2-3
  year: 1995
  ident: R6-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/0169-409X(95)00031-2
– volume: 74
  start-page: 295
  issue: 1-3
  year: 2001
  ident: R106-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00341-8
– volume: 16
  start-page: 113
  issue: 1-4
  year: 1999
  ident: R85-1-20080912
  publication-title: Colloids Surf B Biointerfaces
  doi: 10.1016/S0927-7765(99)00064-8
– volume: 11
  start-page: 269
  issue: 1-3
  year: 1990
  ident: R101-1-20080912
  publication-title: JControl Rel
  doi: 10.1016/0168-3659(90)90139-K
– volume: 54
  start-page: 203
  issue: 2
  year: 2002
  ident: R21-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(02)00017-0
– volume: 16
  start-page: 1373
  issue: 9
  year: 1999
  ident: R149-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1018942823676
– volume: 95
  start-page: 601
  issue: 5
  year: 2006
  ident: R153-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6603311
– volume: 6
  start-page: 2462
  issue: 5
  year: 2005
  ident: R27-1-20080912
  publication-title: Biomacromolecules
  doi: 10.1021/bm0503165
– volume: 61
  start-page: 2541
  issue: 23
  year: 2004
  ident: R61-1-20080912
  publication-title: Am J Health Syst Pharm
  doi: 10.1093/ajhp/61.23.2541
– volume: 12
  start-page: 517
  issue: 8
  year: 2004
  ident: R49-1-20080912
  publication-title: J Drug Target
  doi: 10.1080/10611860400011927
– volume: 18
  start-page: 623
  issue: 7
  year: 1997
  ident: R68-1-20080912
  publication-title: Biopharm Drug Dispos
  doi: 10.1002/(SICI)1099-081X(199710)18:7<623::AID-BDD46>3.0.CO;2-V
– volume: 92
  start-page: 1343
  issue: 7
  year: 2003
  ident: R10-1-20080912
  publication-title: J Pharm Sci
  doi: 10.1002/jps.10397
– volume: 22
  start-page: 2049
  issue: 14
  year: 2001
  ident: R123-1-20080912
  publication-title: Biomaterials
  doi: 10.1016/S0142-9612(00)00393-8
– volume: 202
  start-page: 161
  issue: 1-2
  year: 2000
  ident: R72-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(00)00443-9
– volume: 343
  start-page: 34
  issue: 1-2
  year: 2007
  ident: R75-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2007.04.013
– volume: 31
  start-page: 447
  issue: 4-5
  year: 2005
  ident: R62-1-20080912
  publication-title: Drug Dev Ind Pharm
  doi: 10.1080/03639040500214662
– volume: 30
  start-page: 1138
  issue: 9
  year: 2007
  ident: R30-1-20080912
  publication-title: Arch Pharm Res
  doi: 10.1007/BF02980249
– volume: 24
  start-page: 119
  issue: 1-3
  year: 1993
  ident: R14-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(93)90172-2
– volume: 22
  start-page: 209
  issue: 2
  year: 2005
  ident: R42-1-20080912
  publication-title: Pharm Res
  doi: 10.1007/s11095-004-1188-0
– volume: 54
  start-page: 299
  issue: 3
  year: 2002
  ident: R50-1-20080912
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/S0939-6411(02)00119-4
– volume: 15
  start-page: 215
  issue: 7
  year: 1994
  ident: R3-1-20080912
  publication-title: Trends Pharmacol Sci
  doi: 10.1016/0165-6147(94)90314-X
– volume: 26
  start-page: 7251
  issue: 35
  year: 2005
  ident: R83-1-20080912
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2005.05.042
– volume: 15
  start-page: 441
  issue: 3
  year: 2004
  ident: R137-1-20080912
  publication-title: Bioconjug Chem
  doi: 10.1021/bc034113u
– volume: 329
  start-page: 158
  year: 2007
  ident: R128-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.08.018
– volume: 51
  start-page: 169
  issue: 2-3
  year: 1998
  ident: R129-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(97)00163-6
– volume: 94
  start-page: 323
  issue: 2-3
  year: 2004
  ident: R131-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2003.10.012
– volume: 64
  start-page: 143
  issue: 1-3
  year: 2000
  ident: R108-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(99)00133-9
– volume: 8
  start-page: 1
  issue: 1
  year: 2007
  ident: R76-1-20080912
  publication-title: AAPS Pharm Sci Tech
  doi: 10.1208/pt0801001
– volume: 88
  start-page: 11460
  issue: 24
  year: 1991
  ident: R124-1-20080912
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.88.24.11460
– volume: 16
  start-page: 3
  issue: 1-4
  year: 1999
  ident: R12-1-20080912
  publication-title: Colloids Surf B Biointerfaces
  doi: 10.1016/S0927-7765(99)00058-2
– volume: 10
  start-page: 3708
  issue: 11
  year: 2004
  ident: R115-1-20080912
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-03-0655
– volume: 66
  start-page: 10048
  issue: 20
  year: 2006
  ident: R122-1-20080912
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-06-1605
– volume: 98
  start-page: 415
  issue: 3
  year: 2004
  ident: R136-1-20080912
  publication-title: JControl Rel
  doi: 10.1016/j.jconrel.2004.06.003
– volume: 23
  start-page: 1243
  issue: 6
  year: 2006
  ident: R56-1-20080912
  publication-title: Pharm Res
  doi: 10.1007/s11095-006-0022-2
– volume: 15
  start-page: 850
  issue: 6
  year: 1998
  ident: R147-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1011964213024
– volume: 51
  start-page: 13
  issue: 1
  year: 1998
  ident: R134-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(97)00124-7
– volume: 1066
  start-page: 159
  issue: 2
  year: 1991
  ident: R126-1-20080912
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(91)90182-8
– volume: 13
  start-page: 391
  issue: 7
  year: 2005
  ident: R110-1-20080912
  publication-title: J Drug Target
  doi: 10.1080/10611860500376741
– volume: 92
  start-page: 328
  issue: 3
  year: 2001
  ident: R117-1-20080912
  publication-title: Jpn J Cancer Res
  doi: 10.1111/j.1349-7006.2001.tb01099.x
– volume: 4
  start-page: E40
  issue: 4
  year: 2002
  ident: R57-1-20080912
  publication-title: AAPS Pharm Sci
  doi: 10.1208/ps040440
– volume: 7
  start-page: 171
  issue: 3
  year: 1999
  ident: R105-1-20080912
  publication-title: J Drug Target
  doi: 10.3109/10611869909085500
– volume: 111
  start-page: 47
  issue: 1-2
  year: 2006
  ident: R52-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2005.11.012
– volume: 9
  start-page: 139
  issue: 1
  year: 1999
  ident: R11-1-20080912
  publication-title: STP Pharma Sci
– volume: 303
  start-page: 1818
  issue: 5665
  year: 2004
  ident: R4-1-20080912
  publication-title: Science
  doi: 10.1126/science.1095833
– volume: 21
  start-page: 418
  issue: 4
  year: 1998
  ident: R130-1-20080912
  publication-title: Arch Pharm Res
  doi: 10.1007/BF02974636
– volume: 294
  start-page: 247
  issue: 1-2
  year: 2005
  ident: R35-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2005.01.018
– volume: 21
  start-page: 1184
  issue: 7
  year: 2004
  ident: R133-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/B:PHAM.0000033005.25698.9c
– volume: 8
  start-page: 999
  issue: 13
  year: 2001
  ident: R78-1-20080912
  publication-title: Gene Ther
  doi: 10.1038/sj.gt.3301485
– volume: 126
  start-page: 10640
  issue: 34
  year: 2004
  ident: R69-1-20080912
  publication-title: J Am Chem Soc
  doi: 10.1021/ja039651w
– volume: 89
  start-page: 127
  issue: 1
  year: 2003
  ident: R64-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(03)00094-4
– volume: 29
  start-page: 928
  issue: 10
  year: 2006
  ident: R66-1-20080912
  publication-title: Arch Pharm Res
  doi: 10.1007/BF02973916
– volume: 56
  start-page: 3626
  issue: 16
  year: 1996
  ident: R146-1-20080912
  publication-title: Cancer Res
– volume: 53
  start-page: 466
  issue: 7
  year: 1998
  ident: R74-1-20080912
  publication-title: Pharmazie
– volume: 29
  start-page: 17
  year: 1994
  ident: R104-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(94)90118-X
– volume: 92
  start-page: 1240
  issue: 7
  year: 2005
  ident: R88-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6602479
– volume: 28
  start-page: 334
  issue: 1-3
  year: 1994
  ident: R127-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(94)90203-8
– volume: 105
  start-page: 32
  issue: 1-2
  year: 2005
  ident: R37-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2005.03.018
– volume: 13
  start-page: 1838
  issue: 12
  year: 1996
  ident: R45-1-20080912
  publication-title: Pharm Res
  doi: 10.1023/A:1016085108889
– volume: 65
  start-page: 309
  issue: 3
  year: 2007
  ident: R97-1-20080912
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2006.11.010
– volume: 42
  start-page: 419
  issue: 5
  year: 2003
  ident: R93-1-20080912
  publication-title: Clin Pharmacokinet
  doi: 10.2165/00003088-200342050-00002
– volume: 40
  start-page: 81
  issue: 1
  year: 1997
  ident: R112-1-20080912
  publication-title: Cancer Chemother Pharmacol
  doi: 10.1007/s002800050630
– volume: 2
  start-page: 35
  issue: 1
  year: 2005
  ident: R98-1-20080912
  publication-title: Curr Drug Deliv
  doi: 10.2174/1567201052772852
– volume: 43
  start-page: 489
  issue: 6
  year: 2004
  ident: R73-1-20080912
  publication-title: Prog Lipid Res
  doi: 10.1016/j.plipres.2004.09.001
– volume: 90
  start-page: 2085
  issue: 11
  year: 2004
  ident: R86-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6601856
– volume: 54
  start-page: 169
  issue: 2
  year: 2002
  ident: R17-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(02)00015-7
– volume: 15
  start-page: 481
  issue: 5
  year: 2004
  ident: R24-1-20080912
  publication-title: Hum Gene Ther
  doi: 10.1089/10430340460745801
– volume: 99
  start-page: 83
  issue: 1
  year: 2004
  ident: R100-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.06.018
– volume: 298
  start-page: 176
  issue: 1
  year: 2005
  ident: R36-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2005.04.016
– volume: 54
  start-page: 235
  issue: 2
  year: 2002
  ident: R22-1-20080912
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/S0169-409X(02)00019-4
– volume: 325
  start-page: 155
  issue: 1-2
  year: 2006
  ident: R34-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.06.040
– volume: 47
  start-page: 555
  issue: 6
  year: 2003
  ident: R63-1-20080912
  publication-title: Pharmacol Res
  doi: 10.1016/S1043-6618(03)00043-4
– volume: 118
  start-page: 105
  issue: 1
  year: 2007
  ident: R25-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2006.12.007
– volume: 333
  start-page: 87
  issue: 1-2
  year: 2007
  ident: R41-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2006.10.002
– volume: 132
  start-page: 195
  issue: 1-2
  year: 1996
  ident: R152-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/0378-5173(95)04386-1
– volume: 981
  start-page: 27
  issue: 1
  year: 1989
  ident: R125-1-20080912
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(89)90078-3
– volume: 7
  start-page: 1259
  issue: 9
  year: 2007
  ident: R38-1-20080912
  publication-title: Int Immunopharmacol
  doi: 10.1016/j.intimp.2007.05.003
– volume: 72
  start-page: 191
  issue: 1-3
  year: 2001
  ident: R99-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00275-9
– volume: 7
  start-page: 144
  issue: 1
  year: 1996
  ident: R120-1-20080912
  publication-title: Bioconjug Chem
  doi: 10.1021/bc950089b
– volume: 96
  start-page: 273
  issue: 2
  year: 2004
  ident: R109-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.02.003
– volume: 74
  start-page: 1545
  issue: 10
  year: 1996
  ident: R145-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/bjc.1996.587
– volume: 5
  start-page: 521
  issue: 4
  year: 2000
  ident: R71-1-20080912
  publication-title: Pharm Dev Technol
  doi: 10.1081/PDT-100102035
– volume: 32
  start-page: 269
  year: 1994
  ident: R140-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/0168-3659(94)90237-2
– volume: 101
  start-page: 223
  issue: 1-3
  year: 2005
  ident: R119-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.08.022
– volume: 97
  start-page: 170
  issue: 2
  year: 2007
  ident: R87-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6603855
– volume: 8
  start-page: 431
  year: 1987
  ident: R138-1-20080912
  publication-title: Makromol Chem
  doi: 10.1002/marc.1987.030080903
– volume: 209
  start-page: 1
  issue: 1-2
  year: 2000
  ident: R77-1-20080912
  publication-title: Int J Pharm
  doi: 10.1016/S0378-5173(00)00508-1
– volume: 18
  start-page: 2009
  issue: 12
  year: 2007
  ident: R142-1-20080912
  publication-title: Ann Oncol
  doi: 10.1093/annonc/mdm374
– volume: 42
  start-page: 943
  issue: 1-9
  year: 2004
  ident: R107-1-20080912
  publication-title: Ultrasonics
  doi: 10.1016/j.ultras.2004.01.087
– volume: 102
  start-page: 657
  issue: 3
  year: 2005
  ident: R51-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/j.jconrel.2004.10.022
– volume: 77
  start-page: 155
  issue: 1-2
  year: 2001
  ident: R135-1-20080912
  publication-title: J Control Rel
  doi: 10.1016/S0168-3659(01)00477-1
– volume: 3
  start-page: 139
  issue: 1
  year: 2006
  ident: R1-1-20080912
  publication-title: Expert Opin Drug Del
  doi: 10.1517/17425247.3.1.139
– volume: 91
  start-page: 1775
  issue: 10
  year: 2004
  ident: R89-1-20080912
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6602204
– reference: 11109251 - Pharm Dev Technol. 2000;5(4):521-32
– reference: 9311446 - Anticancer Drugs. 1997 Aug;8(7):696-701
– reference: 1458544 - Crit Rev Ther Drug Carrier Syst. 1992;9(3-4):213-48
– reference: 14959789 - Crit Rev Ther Drug Carrier Syst. 2003;20(5):357-403
– reference: 12695068 - J Control Release. 2003 Apr 14;89(1):127-40
– reference: 2039998 - Cancer Res. 1991 Jun 15;51(12):3229-36
– reference: 7940982 - Trends Pharmacol Sci. 1994 Jul;15(7):215-20
– reference: 11426885 - Biomaterials. 2001 Jul;22(14):2049-56
– reference: 1854781 - Biochim Biophys Acta. 1991 Jul 22;1066(2):159-65
– reference: 17055200 - Int J Pharm. 2007 Mar 6;332(1-2):161-7
– reference: 9794493 - Pharm Res. 1998 Oct;15(10):1525-32
– reference: 11072877 - Life Sci. 2000 Sep 8;67(16):2011-6
– reference: 15526161 - Cell Mol Life Sci. 2004 Oct;61(19-20):2549-59
– reference: 8705995 - Cancer Res. 1996 Aug 15;56(16):3626-9
– reference: 15785749 - Br J Cancer. 2005 Apr 11;92(7):1240-6
– reference: 15150584 - Br J Cancer. 2004 Jun 1;90(11):2085-91
– reference: 17257817 - Eur J Pharm Biopharm. 2007 Mar;65(3):309-19
– reference: 11689268 - J Control Release. 2001 Nov 9;77(1-2):155-60
– reference: 11267944 - Jpn J Cancer Res. 2001 Mar;92(3):328-36
– reference: 14559067 - Prog Lipid Res. 2003 Nov;42(6):463-78
– reference: 16723095 - Acta Pharmacol Sin. 2006 Jun;27(6):747-53
– reference: 11897144 - Adv Drug Deliv Rev. 2002 Feb 21;54(2):169-90
– reference: 17206808 - Biomacromolecules. 2007 Jan;8(1):202-8
– reference: 17476588 - Breast Cancer Res Treat. 2008 Mar;108(2):241-50
– reference: 15814248 - Int J Pharm. 2005 Apr 27;294(1-2):247-59
– reference: 17121190 - Arch Pharm Res. 2006 Oct;29(10):928-33
– reference: 10213370 - Pharm Res. 1999 Mar;16(3):396-401
– reference: 8932333 - Br J Cancer. 1996 Nov;74(10 ):1545-52
– reference: 17968711 - J Drug Target. 2007 Nov;15(9):553-84
– reference: 17724775 - J Gene Med. 2007 Nov;9(11):956-66
– reference: 15342183 - J Control Release. 2004 Sep 14;99(1):83-101
– reference: 10915939 - Int J Pharm. 2000 Jul 20;202(1-2):161-4
– reference: 2719971 - Biochim Biophys Acta. 1989 May 19;981(1):27-35
– reference: 11604255 - Int J Pharm. 2001 Oct 23;229(1-2):29-36
– reference: 17644207 - J Control Release. 2007 Sep 11;122(1):63-70
– reference: 11510630 - Clin Pharmacokinet. 2001;40(7):539-51
– reference: 17628697 - Vet Immunol Immunopathol. 2007 Oct 15;119(3-4):299-302
– reference: 11897146 - Adv Drug Deliv Rev. 2002 Feb 21;54(2):203-22
– reference: 17630205 - Int Immunopharmacol. 2007 Sep;7(9):1259-64
– reference: 11251249 - Adv Drug Deliv Rev. 2001 Mar 23;47(1):113-31
– reference: 17258837 - J Control Release. 2007 Mar 12;118(1):105-17
– reference: 15327322 - J Am Chem Soc. 2004 Sep 1;126(34):10640-4
– reference: 9822868 - Crit Rev Ther Drug Carrier Syst. 1998;15(5):481-512
– reference: 9685900 - J Control Release. 1998 Jan 23;51(1):13-22
– reference: 8742003 - Bioconjug Chem. 1996 Jan-Feb;7(1):144-9
– reference: 17958332 - Arch Pharm Res. 2007 Sep;30(9):1138-43
– reference: 15081218 - J Control Release. 2004 Apr 28;96(2):273-83
– reference: 17785767 - Ann Oncol. 2007 Dec;18(12):2009-14
– reference: 15312997 - J Control Release. 2004 Aug 27;98 (3):415-26
– reference: 12646011 - AAPS PharmSci. 2002;4(4):E40
– reference: 14744484 - J Control Release. 2004 Feb 10;94(2-3):323-35
– reference: 11858520 - Drug Dev Ind Pharm. 2002 Jan;28(1):101-5
– reference: 9330782 - Biopharm Drug Dispos. 1997 Oct;18(7):623-33
– reference: 16153081 - Biomacromolecules. 2005 Sep-Oct;6(5):2462-7
– reference: 16370946 - Expert Opin Drug Deliv. 2006 Jan;3(1):139-62
– reference: 2306723 - Cancer Res. 1990 Mar 15;50(6):1693-700
– reference: 12820139 - J Pharm Sci. 2003 Jul;92(7):1343-55
– reference: 8608176 - Bioconjug Chem. 1995 Nov-Dec;6(6):639-43
– reference: 10881025 - Prostate. 2000 Jul 1;44(2):156-63
– reference: 15144578 - Hum Gene Ther. 2004 May;15(5):481-93
– reference: 10640653 - J Control Release. 2000 Feb 14;64(1-3):143-53
– reference: 17085025 - Eur J Pharm Biopharm. 2007 Apr;66(1):11-20
– reference: 17718968 - J Control Release. 2006 Nov 28;116(2):e53-5
– reference: 8983343 - Bioconjug Chem. 1996 Mar-Apr;7(2):209-16
– reference: 15290858 - Pharm Res. 2004 Jul;21(7):1184-91
– reference: 15477860 - Br J Cancer. 2004 Nov 15;91(10):1775-81
– reference: 12742011 - Pharmacol Res. 2003 Jun;47(6):555-62
– reference: 15031496 - Science. 2004 Mar 19;303(5665):1818-22
– reference: 16460829 - J Control Release. 2006 Mar 10;111(1-2):47-55
– reference: 15950411 - Int J Pharm. 2005 Jul 14;298(1):176-85
– reference: 17097755 - J Control Release. 2007 Jan 22;117(1):59-67
– reference: 16005061 - Biomaterials. 2005 Dec;26(35):7251-9
– reference: 15595229 - Am J Health Syst Pharm. 2004 Dec 1;61(23):2541-4
– reference: 9742041 - Pharmazie. 1998 Jul;53(7):466-9
– reference: 12880295 - Pharm Res. 2003 Jul;20(7):1085-92
– reference: 11897148 - Adv Drug Deliv Rev. 2002 Feb 21;54(2):235-52
– reference: 11084241 - Int J Pharm. 2000 Nov 19;209(1-2):1-14
– reference: 9137535 - Cancer Chemother Pharmacol. 1997;40(1):81-6
– reference: 10469928 - Eur J Pharm Biopharm. 1999 Sep;48(2):101-11
– reference: 16305406 - Curr Drug Deliv. 2005 Jan;2(1):35-44
– reference: 15763623 - J Control Release. 2005 Mar 21;103(2):405-18
– reference: 10353627 - Life Sci. 1999;64(19):1733-8
– reference: 17852364 - Drug Dev Ind Pharm. 2007 Oct;33(10):1142-50
– reference: 10606784 - Int J Pharm. 2000 Jan 5;193(2):213-8
– reference: 9685914 - J Control Release. 1998 Feb 12;51(2-3):169-78
– reference: 14695216 - Cancer Res. 2003 Dec 15;63(24):8977-83
– reference: 11516494 - J Control Release. 2001 Jun 15;73(2-3):137-72
– reference: 16308207 - J Drug Target. 2005 Aug;13(7):391-7
– reference: 12739982 - Clin Pharmacokinet. 2003;42(5):419-36
– reference: 11489509 - J Control Release. 2001 Jul 6;74(1-3):295-302
– reference: 17481869 - Eur J Pharm Biopharm. 2007 Jun;66(3):303-17
– reference: 9647349 - Pharm Res. 1998 Jun;15(6):850-5
– reference: 12538842 - J Pharmacol Exp Ther. 2003 Feb;304(2):845-54
– reference: 16919723 - Biomaterials. 2006 Dec;27(34):5855-60
– reference: 17408209 - AAPS PharmSciTech. 2007 Jan 05;8(1):1
– reference: 10680973 - J Drug Target. 1999;7(3):171-86
– reference: 12033373 - Pharm Res. 2002 Apr;19(4):418-22
– reference: 15783068 - Pharm Res. 2005 Feb;22(2):209-19
– reference: 15567504 - J Control Release. 2004 Dec 10;100(3):389-97
– reference: 11389998 - J Control Release. 2001 May 14;72(1-3):191-202
– reference: 17118588 - Int J Pharm. 2007 Apr 4;334(1-2):156-65
– reference: 11496942 - Pharm Res. 2001 Jul;18(7):1035-41
– reference: 15621677 - J Drug Target. 2004;12(8):517-26
– reference: 16093210 - Drug Dev Ind Pharm. 2005 May;31(4-5):447-54
– reference: 11438834 - Gene Ther. 2001 Jul;8(13):999-1004
– reference: 15522762 - Prog Lipid Res. 2004 Nov;43(6):489-533
– reference: 1763060 - Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11460-4
– reference: 16805949 - J Pharm Pharmacol. 2006 Jul;58(7):903-8
– reference: 17008034 - Int J Pharm. 2007 Feb 1;329(1-2):158-65
– reference: 15149170 - Bioconjug Chem. 2004 May-Jun;15(3):441-8
– reference: 16909136 - Br J Cancer. 2006 Sep 4;95(5):601-6
– reference: 16715372 - Pharm Res. 2006 Jun;23(6):1243-50
– reference: 8378259 - Pharm Res. 1993 Jul;10(7):970-4
– reference: 10496652 - Pharm Res. 1999 Sep;16(9):1373-9
– reference: 12445560 - Eur J Pharm Biopharm. 2002 Nov;54(3):299-309
– reference: 16884870 - Int J Pharm. 2006 Nov 15;325(1-2):155-62
– reference: 16222314 - Br J Cancer. 2005 Sep 19;93(6):678-87
– reference: 15681087 - J Control Release. 2005 Feb 16;102(3):657-68
– reference: 15173077 - Clin Cancer Res. 2004 Jun 1;10(11):3708-16
– reference: 9875469 - Arch Pharm Res. 1998 Aug;21(4):418-22
– reference: 15925422 - J Control Release. 2005 Jun 20;105(1-2):32-42
– reference: 15907580 - J Control Release. 2005 May 18;104(2):289-300
– reference: 17047068 - Cancer Res. 2006 Oct 15;66(20):10048-56
– reference: 15588907 - J Control Release. 2005 Jan 3;101(1-3):223-32
– reference: 15047411 - Ultrasonics. 2004 Apr;42(1-9):943-50
– reference: 17081709 - Int J Pharm. 2007 Mar 21;333(1-2):87-94
– reference: 8987081 - Pharm Res. 1996 Dec;13(12):1838-45
– reference: 17595665 - Br J Cancer. 2007 Jul 16;97(2):170-6
– reference: 11755705 - Adv Drug Deliv Rev. 2002 Jan 17;54(1):37-51
– reference: 17537601 - Int J Pharm. 2007 Oct 1;343(1-2):34-40
– reference: 2065067 - Biochim Biophys Acta. 1991 Jul 1;1066(1):29-36
– reference: 9361956 - Drugs. 1997;54 Suppl 4:8-14
– reference: 12608532 - Pharm Res. 2003 Jan;20(1):24-30
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Snippet Since their discovery in the early 1980s, polymeric micelles have been the subject of several studies as delivery systems that can potentially improve the...
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SubjectTerms Animals
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - adverse effects
Biological and medical sciences
Drug Delivery Systems
General pharmacology
Humans
Internal Medicine
Leading Article
Medical sciences
Medicine
Medicine & Public Health
Micelles
Neoplasms - drug therapy
Pharmaceutical Preparations - administration & dosage
Pharmaceutical Preparations - metabolism
Pharmaceutical technology. Pharmaceutical industry
Pharmacokinetics
Pharmacology. Drug treatments
Pharmacology/Toxicology
Pharmacotherapy
Polymers
Tissue Distribution
Subtitle From Discovery to Recovery
Title Disposition of Drugs in Block Copolymer Micelle Delivery Systems
URI https://link.springer.com/article/10.2165/00003088-200847100-00001
https://www.ncbi.nlm.nih.gov/pubmed/18783294
https://www.proquest.com/docview/222742643
https://www.proquest.com/docview/69539166
Volume 47
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