Neuropathology associated with exposure to different concentrations and species of mercury: A review of autopsy cases and the literature

• Published in: Neurotoxicology (Park Forest South) Vol. 78; pp. 88 - 98
• Main Authors: O’Donoghue, John L., Watson, Gene E., Brewer, Rubell, Zareba, Grazyna, Eto, Komyo, Takahashi, Hitoshi, Marumoto, Masumi, Love, Tanzy, Harrington, Donald, Myers, Gary J.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2020; Elsevier BV
• Subjects: Abnormalities; Adults; Amalgams; Animals; Astrocytes; Autopsies; Autopsy; Brain; Brain - drug effects; Brain - pathology; Brain Chemistry - drug effects; Brain stem; Case reports; Central nervous system; Cerebellum; Consumption; Dental amalgams; Dental restorative materials; Deposition; Diet; Dimethylmercury; Endothelial cells; Environmental Exposure; Exposure; Fish; Fishes; Humans; Inorganic mercury; Intravenous administration; Mercury; Mercury (metal); Methyl mercury; Methylmercury Compounds - toxicity; Microglia; Motor neurons; Neuronal-glial interactions; Neurons; Neurons - drug effects; Neurons - pathology; Neuropathology; Organic mercury; Paraffin; Paraffins; Purkinje cells; Pyramidal cells; Seychelles; Species; Seychelles; Organic mercury; Inorganic mercury; Neuropathology; Mercury; Methyl mercury; Seychelles

•Mean total mercury in the cerebrum of people with no known exposure was 16 ppb.•Mean total mercury in the cerebrum of Seychellois consuming fish was 129−182 ppb.•No pathology was observed in the brains of Seychellois who consumed fish regularly.•Total brain mercury approaches steady state during ge...