Early Mortality in a Multinational Systemic Sclerosis Inception Cohort

• Published in: Arthritis & rheumatology (Hoboken, N.J.) Vol. 69; no. 5; pp. 1067 - 1077
• Main Authors: Hao, Yanjie, Hudson, Marie, Baron, Murray, Carreira, Patricia, Stevens, Wendy, Rabusa, Candice, Tatibouet, Solene, Carmona, Loreto, Joven, Beatriz E., Huq, Molla, Proudman, Susanna, Nikpour, Mandana, Abu‐Hakima, M., Baron, M., Cabral, A. R., Docherty, P., Fortin, P. R., Fritzler, M., Grodzicky, T., Gyger, G., Hudson, M., Jones, N., Kaminska, E., Khalidi, N., Larché, M., LeClercq, S., Ligier, S., Markland, J., Masetto, A., Mathieu, J.‐P., Pope, J., Robinson, D., Rodriguez‐Reyna, T. S., Smith, D., Sutton, E., Thorne, C., Nikpour, M., Proudman, S., Roddy, J., Sahhar, J., Stevens, W., Walker, J., Youssef, P., Zochling, J.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2017
• Subjects: Adult; Aged; Australia; Autoantibodies - immunology; Canada; Cause of Death; Cerebrovascular Disorders - mortality; Cohort Studies; Confidence intervals; Coronary artery disease; Death; Fatalities; Female; Health risk assessment; Heart diseases; Heart Diseases - etiology; Heart Diseases - mortality; Humans; Hypertension; Hypertension, Pulmonary - etiology; Hypertension, Pulmonary - mortality; Intestinal Diseases - etiology; Intestinal Diseases - mortality; Ischemia; Kaplan-Meier Estimate; Kidney Diseases - etiology; Kidney Diseases - mortality; Kidneys; Lung diseases; Lung Diseases, Interstitial - etiology; Lung Diseases, Interstitial - mortality; Male; Malignancy; Men; Middle Aged; Mortality; Myocardial Ischemia - mortality; Neoplasms - mortality; Prognosis; Pulmonary hypertension; Scleroderma; Scleroderma, Systemic - complications; Scleroderma, Systemic - immunology; Scleroderma, Systemic - mortality; Sepsis; Sepsis - mortality; Spain; Systemic sclerosis

Objective To determine mortality and causes of death in a multinational inception cohort of subjects with systemic sclerosis (SSc). Methods We quantified mortality as standardized mortality ratio (SMR), years of life lost, and percentage mortality in the first decade of disease. The inception cohort...