Integration of metabolomics and machine learning revealed tryptophan metabolites are sensitive biomarkers of pemetrexed efficacy in non‐small cell lung cancer - Sun, Runbin; Fei, Fei; Wang, Min; Jiang, Junyi; Yang, Guangyu; Yang, Na; Jin, Dandan; Xu, Zhi; Cao, Bei; Li, Juan (Cancer medicine (Malden, MA), 2023)
Keywords: Acids; Algorithms; Artificial intelligence; Biomarkers; Cancer therapies; Chemotherapy; Data analysis; Discriminant analysis; Disease; Drug efficacy; Drug resistance; Efficiency; Epidemics; Folic acid; Hospitals; Infections; Learning algorithms; Lung cancer; Machine learning; Mathematical models; Metabolism; Metabolites; Metabolomics; Methods; Non-small cell lung carcinoma; NSCLC; Patients; pemetrexed; pharmacometabolomics; Pyruvic acid; Small cell lung carcinoma; Threonine; Tricarboxylic acid cycle; Tryptophan; Tumors; Vitamin B; China