Longitudinal assessment of spinal cord injuries in nonhuman primates with quantitative magnetization transfer

• Published in: Magnetic resonance in medicine Vol. 75; no. 4; pp. 1685 - 1696
• Main Authors: Wang, Feng, Li, Ke, Mishra, Arabinda, Gochberg, Daniel, Min Chen, Li, Gore, John C.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.04.2016; Wiley Subscription Services, Inc
• Subjects: 9.4T; Animals; Anisotropy; Brain - diagnostic imaging; Brain - pathology; cyst; Cysts; Demyelinating Diseases - diagnostic imaging; Demyelination; Diffusion coefficient; Diffusion rate; Image Processing, Computer-Assisted - methods; Injuries; Lesions; Macromolecules; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Magnetization; Male; MRI; Parameter robustness; quantitative magnetization transfer (qMT); Reproducibility; Saimiri; Spinal cord injuries; Spinal Cord Injuries - diagnostic imaging; Spinal Cord Injuries - pathology; spinal cord injury; Substantia alba; Substantia grisea; spinal cord injury; cyst; quantitative magnetization transfer (qMT); MRI; demyelination; 9.4T

Purpose This study aimed to evaluate the reproducibility and specificity of quantitative magnetization transfer (qMT) imaging for monitoring spinal cord injuries (SCIs). Methods MRI scans were performed in anesthetized monkeys at 9.4T, before and serially after a unilateral lesion of the cervical sp...