Copeptin: clinical use of a new biomarker

• Published in: Trends in endocrinology and metabolism Vol. 19; no. 2; pp. 43 - 49
• Main Authors: Morgenthaler, Nils G., Struck, Joachim, Jochberger, Stefan, Dünser, Martin W.
• Format: Journal Article
• Language: English
• Published: London Elsevier Ltd 01.03.2008; Elsevier
• Subjects: Arginine Vasopressin - metabolism; Arginine Vasopressin - physiology; Biological and medical sciences; Biomarkers - analysis; Biomarkers - chemistry; Diabetes Insipidus - diagnosis; Endocrinology & Metabolism; Fundamental and applied biological sciences. Psychology; Glycopeptides - analysis; Glycopeptides - chemistry; Heart Failure - blood; Humans; Models, Biological; Sepsis - blood; Shock - diagnosis; Vertebrates: endocrinology; Water-Electrolyte Imbalance - diagnosis; Biological marker

Arginine vasopressin (AVP) is a key hormone in the human body. Despite the clinical relevance of AVP in maintaining fluid balance and vascular tone, measurement of mature AVP is difficult and subject to preanalytical errors. Recently, copeptin, a 39-amino acid glycopeptide that comprises the C-termi...