Major determinants and possible mechanism of dobutamine-induced left ventricular outflow tract obstruction in patients with a sigmoid ventricular septum

• Published in: Journal of cardiology Vol. 61; no. 6; pp. 428 - 435
• Main Authors: Tano, Ayako, Kasamaki, Yuji, Okumura, Yasuo, Ohta, Masakatsu, Kofune, Tatsuya, Fujii, Nobuyuki, Aizawa, Yosihiro, Nakai, Toshiko, Kunimoto, Satoshi, Hiro, Takafumi, Watanabe, Ichiro, Hirayama, Atsushi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.06.2013
• Subjects: Aged; Aged, 80 and over; Aging - pathology; Cardiovascular; Dobutamine; Dobutamine stress echocardiography; Echocardiography, Stress; Female; Humans; Latent left ventricular outflow tract obstruction; Male; Sigmoid septum; Ventricular Outflow Obstruction - diagnostic imaging; Ventricular Outflow Obstruction - etiology; Ventricular Outflow Obstruction - physiopathology; Ventricular Septum - diagnostic imaging; Ventricular Septum - pathology; Ventricular Septum - physiopathology; Dobutamine stress echocardiography; Latent left ventricular outflow tract obstruction; Sigmoid septum

A sigmoid ventricular septum (SVS) may be related to normal aging, but some people with an SVS develop a left ventricular outflow tract (LVOT) obstruction (defined as a gradient of >30mmHg). Therefore, we investigated the association of LVOT obstructions with an SVS by dobutamine stress echocardi...