Changes in gene expression profiles in patients with pulmonary arterial hypertension associated with scleroderma treated with tadalafil - Cheong, Fei-Ying; Gower, Adam C.; Farber, Harrison W. (Seminars in arthritis and rheumatism, 2017)
Keywords: Aged; Down-Regulation; Extracellular Matrix - genetics; Female; Gene profiling; Golgi Apparatus - genetics; Humans; Hypertension, Pulmonary - drug therapy; Hypertension, Pulmonary - etiology; Hypertension, Pulmonary - genetics; Hypertension, Pulmonary - metabolism; Immunity, Innate - genetics; Interleukin-12 - genetics; Male; Microarray Analysis; Middle Aged; Natriuretic Peptide, Brain - metabolism; Phosphodiesterase 5 Inhibitors - therapeutic use; Pilot Projects; Potassium Channels, Voltage-Gated - genetics; Pulmonary arterial hypertension; Rheumatology; Scleroderma; Scleroderma, Systemic - complications; Scleroderma-associated pulmonary arterial hypertension; Signal Transduction - genetics; Systemic sclerosis; Tadalafil - therapeutic use; Transcriptome; Treatment Outcome; Up-Regulation; Walk Test; Pulmonary arterial hypertension; Scleroderma; Systemic sclerosis; Scleroderma-associated pulmonary arterial hypertension; Gene profiling