Metabolomic analysis of the saliva of Japanese patients with oral squamous cell carcinoma

• Published in: Oncology reports Vol. 37; no. 5; pp. 2727 - 2734
• Main Authors: Ohshima, Mitsuyoshi, Sugahara, Keisuke, Kasahara, Kiyohiro, Katakura, Akira
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.05.2017; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: 3-Hydroxybutyric Acid - analysis; 3-Hydroxybutyric Acid - metabolism; Acids; Aged; Asian Continental Ancestry Group; biomarker; Biomarkers; Biomarkers, Tumor - analysis; Biomarkers, Tumor - metabolism; Cancer patients; Capillary electrophoresis; capillary electrophoresis-mass spectrometry; Carcinoma, Squamous Cell - metabolism; Case-Control Studies; Classification; Disease; Electrophoresis, Capillary - methods; Female; Health aspects; Humans; Japanese; Male; Mass spectrometry; Mass Spectrometry - methods; Metabolism; Metabolites; Metabolome; Metabolomics; Metabolomics - methods; Metastasis; Middle Aged; Mouth cancer; Mouth Neoplasms - metabolism; Oral cancer; oral squamous cell carcinoma; Patients; saliva; Saliva - metabolism; Salivary diagnostics; Software; Squamous cell carcinoma; Stainless steel; Studies; Japan

The aim of the present study was to characterize the metabolic systems in Japanese patients with oral squamous cell carcinoma (OSCC) using capillary electrophoresis-mass spectrometry (CE-MS) metabolome analysis of saliva samples. A previous study showed variations among ethnicities and tumor sites i...