The diagnostic value of soluble urokinase plasminogen activator receptor (suPAR) compared to C-reactive protein (CRP) and procalcitonin (PCT) in children with systemic inflammatory response syndrome (SIRS)

• Published in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Vol. 23; no. 1; pp. 17 - 22
• Main Authors: Şirinoğlu, Melis, Soysal, Ahmet, Karaaslan, Ayşe, Kepenekli Kadayifci, Eda, Yalındağ-Öztürk, Nilüfer, Cinel, İsmail, Yaman, Ali, Haklar, Goncagül, Şirikci, Önder, Turan, Serap, Altınkanat Gelmez, Gülşen, Söyletir, Güner, Bakır, Mustafa
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2017
• Subjects: C-Reactive Protein - metabolism; Calcitonin - blood; Case-Control Studies; Child; Child, Preschool; Children; Female; Hematology, Oncology and Palliative Medicine; Humans; Male; Prognosis; Prospective Studies; Protein Precursors - blood; Receptors, Urokinase Plasminogen Activator - blood; ROC Curve; Sensitivity and Specificity; SIRS; Soluble urokinase plasminogen activator receptor; Systemic Inflammatory Response Syndrome - blood; Systemic Inflammatory Response Syndrome - diagnosis; Systemic Inflammatory Response Syndrome - metabolism; SIRS; Soluble urokinase plasminogen activator receptor; Children

The aim of the present study was to determine the diagnostic and prognostic values of suPAR and to compare them to CRP and PCT in pediatric patients with systemic inflammatory response syndrome (SIRS). A prospective case-control study was performed.The study was performed in a tertiary university ho...