Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adult gpt-delta transgenic mice - Cao, Xuefei; Mittelstaedt, Roberta A.; Pearce, Mason G.; Allen, Bruce C.; Soeteman-Hernández, Lya G.; Johnson, George E.; Bigger, C. Anita H.; Heflich, Robert H. (Environmental and molecular mutagenesis, 2014)
Keywords: Animals; benchmark dose; bilinear model; Bone marrow; DNA Damage - drug effects; DNA Damage - genetics; dose-response; Dose-Response Relationship, Drug; Escherichia coli Proteins - physiology; Ethyl Methanesulfonate - toxicity; gene mutation; Genotoxicity; gpt; Hypoxanthine Phosphoribosyltransferase - genetics; Lac Operon - genetics; Male; Membrane Proteins - genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; micronucleus; Micronucleus Tests; Mutagenicity; Mutagens; Mutagens - toxicity; Mutation; Mutation - genetics; Mutation Rate; NOGEL; Pentosyltransferases - physiology; Pig-a; Reticulocytes - drug effects; Spleen - drug effects; threshold; micronucleus; gene mutation; dose-response; benchmark dose; Pig-a; gpt; threshold; bilinear model; NOGEL