A common plan for dorsoventral patterning in Bilateria

• Published in: Nature (London) Vol. 380; no. 6569; pp. 37 - 40
• Main Authors: De Robertis, E. M, Sasai, Yoshiki
• Format: Journal Article
• Language: English
• Published: London Nature Publishing 07.03.1996; Nature Publishing Group
• Subjects: Animals; Biological and medical sciences; Biological Evolution; Biology; Bone Morphogenetic Proteins; Drosophila; Drosophila Proteins; Embryo, Mammalian - anatomy & histology; Embryo, Nonmammalian - anatomy & histology; Embryonic Induction; Evolution; Fundamental and applied biological sciences. Psychology; Genetics of eukaryotes. Biological and molecular evolution; Glycoproteins; Insect Hormones - physiology; Intercellular Signaling Peptides and Proteins; Mammals; Proteins - physiology; Vertebrates; Xenopus; Vertebrata; Gene; Interspecific comparison; Biological evolution; Central nervous system; Development; Homology; Gene expression; Invertebrata; Axial symmetry; Dorsoventral axis

Functional studies seem now to confirm, as first suggested by E. Geoffroy Saint-Hilaire in 1822, that there was an inversion of the dorsoventral axis during animal evolution. A conserved system of extracellular signals provides positional information for the allocation of embryonic cells to specific...