Obesity and infectious diseases: pathophysiology and epidemiology of a double pandemic condition

• Published in: International Journal of Obesity Vol. 46; no. 3; pp. 449 - 465
• Main Authors: Pugliese, Gabriella, Liccardi, Alessia, Graziadio, Chiara, Barrea, Luigi, Muscogiuri, Giovanna, Colao, Annamaria
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.03.2022; Nature Publishing Group
• Subjects: 692/163/2743/393; 692/700/2814; Adaptive immunity; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics; Antiinfectives and antibacterials; Child; Child, Preschool; Cofactors; Communicable Diseases - epidemiology; Communicable Diseases - physiopathology; Comorbidity; COVID-19; Epidemiology; Female; Gastrointestinal surgery; Health Promotion and Disease Prevention; Humans; Immune response; Impairment; Infant; Infant, Newborn; Infections; Infectious diseases; Internal Medicine; Male; Medicine; Medicine & Public Health; Metabolic Diseases; Middle Aged; Obesity; Obesity - epidemiology; Obesity - physiopathology; Orthopedics; Pandemics; Prevalence; Public awareness; Public Health; Respiratory tract; Respiratory tract diseases; Review Article; Risk analysis; Risk factors; SARS-CoV-2; Surgical site infections; Urinary tract; Viral diseases; Vitamin D; Vitamin D Deficiency; Vitamin deficiency; Wound healing; Young Adult

The current pandemic due to widespread SARS-CoV-19 infection has again highlighted the role of obesity, whose global prevalence increased up to 13%, as a risk factor for both susceptibility to infections and the occurrence of a more severe disease course. To date, this association has not been suffi...