Aspergillosis Case-Fatality Rate: Systematic Review of the Literature

• Published in: Clinical infectious diseases Vol. 32; no. 3; pp. 358 - 366
• Main Authors: Lin, Swu-Jane, Schranz, Jennifer, Teutsch, Steven M.
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 01.02.2001; University of Chicago Press
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; AIDS; Amphotericin B - therapeutic use; Antifungal Agents - therapeutic use; Antifungals; Aspergillosis; Aspergillosis - complications; Aspergillosis - drug therapy; Aspergillosis - mortality; Aspergillus; Biological and medical sciences; Bone marrow; Bone marrow diseases; Bone Marrow Transplantation - mortality; Case-Control Studies; Central Nervous System Fungal Infections - mortality; Child; Child, Preschool; Clinical Trials as Topic; Cohort Studies; Drug Combinations; Female; Human mycoses; Humans; Infections; Infectious diseases; Lung diseases; Lungs; Major Article; Male; Medical sciences; MEDLINE; Middle Aged; Mortality; Mycoses; Mycoses of the respiratory system; Neutropenia - complications; Phosphatidylcholines - therapeutic use; Phosphatidylglycerols - therapeutic use; Prognosis; Infection; Human; Prognosis; Mycosis; Critically ill; Mortality; Aspergillosis; Risk factor; Definition; Review; Localization; Bibliographic review

To update the case-fatality rate (CFR) associated with invasive aspergillosis according to underlying conditions, site of infection, and antifungal therapy, data were systematically reviewed and pooled from clinical trials, cohort or case-control studies, and case series of ⩾10 patients with definit...