Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores - Weissbrod, Omer; Kanai, Masahiro; Shi, Huwenbo; Gazal, Steven; Peyrot, Wouter J.; Khera, Amit V.; Okada, Yukinori; Martin, Alicia R.; Finucane, Hilary K.; Price, Alkes L. (Nature genetics, 2022)
Keywords: 631/208/2489; 692/699; Accuracy; Agriculture; Animal Genetics and Genomics; Biobanks; Biomedical and Life Sciences; Biomedicine; Cancer Research; Estimates; Gene Function; Genome-Wide Association Study; Genomes; Human Genetics; Humans; Linkage Disequilibrium; Mapping; Methods; Multifactorial Inheritance - genetics; Polygenic inheritance; Polymorphism, Single Nucleotide - genetics; Populations; Risk; Risk Factors; Simulation; Training; United Kingdom--UK