Graphene-integrated mesh electronics with converged multifunctionality for tracking multimodal excitation-contraction dynamics in cardiac microtissues

• Published in: Nature communications Vol. 15; no. 1; pp. 2321 - 12
• Main Authors: Gao, Hongyan, Wang, Zhien, Yang, Feiyu, Wang, Xiaoyu, Wang, Siqi, Zhang, Quan, Liu, Xiaomeng, Sun, Yubing, Kong, Jing, Yao, Jun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 14.03.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 639/166/987; 639/925/918/1052; 639/925/927/356; Bioelectricity; Biomechanics; Convergence; Dynamics; Electronics; Excitation; Finite element method; Graphene; Graphite; Heart; Humanities and Social Sciences; Modelling; multidisciplinary; Science; Science (multidisciplinary); Sensor arrays; Softness; Tissue engineering; Tissue Engineering - methods; Tracking

Cardiac microtissues provide a promising platform for disease modeling and developmental studies, which require the close monitoring of the multimodal excitation-contraction dynamics. However, no existing assessing tool can track these multimodal dynamics across the live tissue. We develop a tissue-...