Appropriate glycemic management protects the germline but not the uterine environment in hyperglycemia

Emerging evidence indicates that parental diseases can impact the health of subsequent generations through epigenetic inheritance. Recently, it was shown that maternal diabetes alters the metaphase II oocyte transcriptome, causing metabolic dysfunction in offspring. However, type 1 diabetes (T1D) mo...

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Bibliographic Details
Published inEMBO reports Vol. 25; no. 4; pp. 1752 - 1772
Main Authors Zhao, Allan, Jiang, Hong, Palomares, Arturo Reyes, Larsson, Alice, He, Wenteng, Grünler, Jacob, Zheng, Xiaowei, Rodriguez Wallberg, Kenny A, Catrina, Sergiu-Bogdan, Deng, Qiaolin
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 12.04.2024
Subjects
Biomedical and Life Sciences
EMBO11
EMBO21
Life Sciences
Fetal Development
Hypoxia
Placenta
Diabetes
Developmental Programming
Online AccessGet full text
ISSN1469-3178
1469-221X
1469-3178
DOI10.1038/s44319-024-00097-7

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