Pueraria protein extract inhibits melanogenesis and promotes melanoma cell apoptosis through the regulation of MITF and mitochondrial‑related pathways - Zhao, Yuchu; Yu, Shiting; Wang, Yue; Chen, Yanyan; Chen, Jingjing; Wang, Jiawen; Liu, Meichen; Wang, Siming (Molecular medicine reports, 2023)
Keywords: Adenosine Triphosphate; Amino acids; Animals; Apoptosis; Beans; Care and treatment; Cell Line, Tumor; Cell viability; Cellular signal transduction; Chemical properties; Dehydrogenases; Energy metabolism; Ethanol; Flavonoids; Food safety; Health aspects; Legumes; MAP kinase; Materia medica, Vegetable; Medicine, Chinese; Melanin; Melanins; Melanoma; Melanoma, Experimental - metabolism; Membrane potential; Mice; Microphthalmia-associated transcription factor; Microphthalmia-Associated Transcription Factor - genetics; Microphthalmia-Associated Transcription Factor - metabolism; Mimosaceae; Mitochondria; Mitochondria - metabolism; Monophenol Monooxygenase - metabolism; Pharmacology, Experimental; Plant extracts; Proteins; Pueraria; Pueraria lobata; Reactive oxygen species; Reagents; Safety standards; Skin; Succinate dehydrogenase; Traditional Chinese medicine; Transcription factors; China; melanogenesis; microphthalmia-associated transcription factor; apoptosis; Pueraria Lobata protein; mitochondrial membrane potential