Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein

• Published in: Nature (London) Vol. 333; no. 6170; p. 269
• Main Authors: Homans, S W, Ferguson, M A, Dwek, R A, Rademacher, T W, Anand, R, Williams, A F
• Format: Journal Article
• Language: English
• Published: England 19.05.1988
• Subjects: Animals; Antigens, Surface; Brain - immunology; Carbohydrate Conformation; Carbohydrate Sequence; Cell Membrane - immunology; Magnetic Resonance Spectroscopy; Methylation; Molecular Sequence Data; Phosphatidylinositols; Rats; Thy-1 Antigens

Glycosyl-phosphatidylinositol (GPI) anchors have recently been identified as alternatives to hydrophobic amino acid sequences for the attachment of a variety of eukaryotic cell surface molecules to the lipid bilayer. In single cell eukaryotes the GPI group appears to be the predominant form of membr...