White matter connections reflect changes in voluntary-guided saccades in pre-symptomatic Huntington's disease - Klöppel, Stefan; Draganski, Bogdan; Golding, Charlotte V.; Chu, Carlton; Nagy, Zoltan; Cook, Philip A.; Hicks, Stephen L.; Kennard, Christopher; Alexander, Daniel C.; Parker, Geoff J. M.; Tabrizi, Sarah J.; Frackowiak, Richard S. J. (Brain (London, England : 1878), 2008)
Keywords: Adult; Anisotropy; Biological and medical sciences; Brain - pathology; Brain Mapping - methods; Corpus Striatum - pathology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Diffusion Magnetic Resonance Imaging - methods; Female; Frontal Lobe - pathology; gene carriers; Heterozygote; Humans; Huntington Disease - genetics; Huntington Disease - pathology; Huntington Disease - physiopathology; Male; Medical sciences; Middle Aged; Nerve Fibers - pathology; Neural Pathways - pathology; Neurology; presymptomatic Huntington's disease; Saccades; white matter; presymptomatic Huntington's disease; white matter; saccades; gene carriers; Nervous system diseases; Central nervous system disease; Huntington disease; Degenerative disease; Carrier; White matter; Genetic disease; Cerebral disorder; Extrapyramidal syndrome