Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid - Dedes, P.G.; Gialeli, Ch; Tsonis, A.I.; Kanakis, I.; Theocharis, A.D.; Kletsas, D.; Tzanakakis, G.N.; Karamanos, N.K. (Biochimica et biophysica acta, 2012)
Keywords: Adhesion; antineoplastic agents; Blotting, Western; Bone Density Conservation Agents - pharmacology; Breast cancer; breast neoplasms; Breast Neoplasms - drug therapy; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; cell adhesion; Cell Adhesion - drug effects; Cell Movement - drug effects; Cell Proliferation - drug effects; Diphosphonates - pharmacology; Extracellular matrix; Extracellular Matrix - metabolism; Extracellular Matrix Proteins - genetics; Extracellular Matrix Proteins - metabolism; Female; functional properties; gene expression; Gene Expression Regulation, Neoplastic - drug effects; heparan sulfate; Humans; hyaluronic acid; Imidazoles - pharmacology; integrins; Invasion; metalloproteinases; metastasis; Migration; neoplasm cells; proteoglycans; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; Tumor Cells, Cultured; Wound Healing - drug effects; Zoledronate; LN; BPs; Migration; FN; Breast cancer; COL-IV; Zoledronate; Adhesion; ECM; Invasion; MT-MMP; COL II; MMP; FAK; ZOL; PG; VN; HA; TIMPs; Extracellular matrix; TN; COL I; PKCa