Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis

• Published in: Regional anesthesia and pain medicine Vol. 43; no. 1; pp. 84 - 91
• Main Authors: Davis, Tim, Loudermilk, Eric, DePalma, Michael, Hunter, Corey, Lindley, David, Patel, Nilesh, Choi, Daniel, Soloman, Marc, Gupta, Anita, Desai, Mehul, Buvanendran, Asokumar, Kapural, Leonardo
• Format: Journal Article
• Language: English
• Published: England Copyright by American Society of Regional Anesthesia and Pain Medicine 01.01.2018; BMJ Publishing Group LTD; Lippincott Williams & Wilkins
• Subjects: Ablation; Adrenal Cortex Hormones - administration & dosage; Adrenal Cortex Hormones - adverse effects; Aged; Analgesics - therapeutic use; Arthralgia - diagnosis; Arthralgia - etiology; Arthralgia - physiopathology; Arthralgia - therapy; Arthritis; Betamethasone - administration & dosage; Betamethasone - adverse effects; Catheter Ablation - adverse effects; Chronic and Interventional Pain: Original; Clinical trials; Combined Modality Therapy; Cross-Over Studies; Denervation - adverse effects; Denervation - methods; Female; Humans; Immunomodulators; Injection; Injections, Intra-Articular; Knee; Knee Joint - drug effects; Knee Joint - innervation; Knee Joint - surgery; Male; Methylprednisolone - administration & dosage; Methylprednisolone - adverse effects; Methylprednisolone - analogs & derivatives; Methylprednisolone Acetate; Middle Aged; Osteoarthritis; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - diagnosis; Osteoarthritis, Knee - physiopathology; Osteoarthritis, Knee - therapy; Pain; Pain management; Pain Measurement; Prospective Studies; Quality of life; Regional anesthesia; Time Factors; Treatment Outcome; Triamcinolone Acetonide - administration & dosage; Triamcinolone Acetonide - adverse effects; United States

BACKGROUND AND OBJECTIVESOsteoarthritis (OA) of the knee affects the aging population and has an associated influence on the health care system. Rigorous studies evaluating radiofrequency ablation for OA-related knee pain are lacking. This study compared long-term clinical safety and effectiveness o...