iTRAQ-Based Quantitative Proteomic Analysis Reveals Changes in Metabolite Biosynthesis in Monascus purpureus in Response to a Low-Frequency Magnetic Field

• Published in: Toxins Vol. 10; no. 11; p. 440
• Main Authors: Zhang, Jialan, Liu, Yingbao, Li, Li, Gao, Mengxiang
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.10.2018; MDPI
• Subjects: Annotations; Antioxidants; Biomass; Biosynthesis; Citrinin; Cytochrome; Fatty acids; Fermentation; Genes; Genetic engineering; Kinases; LF-MF; Liquid chromatography; Magnetic fields; Mass spectrometry; Mass spectroscopy; Metabolism; Metabolites; monacolin K; Monascus; Monascus purpureus; Mycelia; pigment; Pigments; protein expression; Protein turnover; Proteins; Red pigments; Signal transduction; Statistical analysis; Statistical methods; Monascus purpureus; pigment; citrinin; LF-MF; monacolin K; protein expression

Background: Low-frequency magnetic fields (LF-MFs) dampen the citrinin output by Monascus purpureus in fermentations. The influence of LF-MFs on biosynthesis by M. purpureus was evaluated at the protein level. Methods: Cultures were treated with a 1.6-mT MF from day 0 to day 2 of incubation, and sec...