Lemon Peel Water Extract: A Novel Material for Retinal Health, Protecting Retinal Pigment Epithelial Cells against Dynamin-Related Protein 1-Mediated Mitochondrial Fission by Blocking ROS-Stimulated Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway - Tsou, Shang-Chun; Chuang, Chen-Ju; Wang, Inga; Chen, Tzu-Chun; Yeh, Jui-Hsuan; Hsu, Chin-Lin; Hung, Yu-Chien; Lee, Ming-Chung; Chang, Yuan-Yen; Lin, Hui-Wen (Antioxidants, 2024)
Keywords: Acidification; Acids; Age; Aluminum; Antioxidants; Apoptosis; Bioavailability; By products; Caspase-3; Cell culture; Cell death; Chromatography; Citrus; Citrus fruits; Dynamin; Epithelium; Ethylenediaminetetraacetic acid; Extracellular signal-regulated kinase; Flavonoids; Kinases; lemon peel ultrasonic-assisted water extract (LUWE); lemon peels; Macular degeneration; MAP kinase; Mitochondria; mitogen-activated protein kinase; Mitogens; Molecular modelling; Oral administration; Oxidative stress; oxygen; Phenols; Polyphenols; protein synthesis; Proteins; Reactive oxygen species; reactive oxygen species (ROS); Retina; Retinal degeneration; Retinal pigment epithelium; Sodium; sodium iodate (NaIO3); Solvents; Taiwan; United States--US; apoptosis; retinal degeneration; reactive oxygen species (ROS); lemon peel ultrasonic-assisted water extract (LUWE); sodium iodate (NaIO3)