Platelets: The Emerging Clinical Diagnostics and Therapy Selection of Cancer Liquid Biopsies

• Published in: OncoTargets and therapy Vol. 14; pp. 3417 - 3428
• Main Authors: Meng, Yiming, Sun, Jing, Zheng, Yang, Zhang, Guirong, Yu, Tao, Piao, Haozhe
• Format: Journal Article
• Language: English
• Published: Macclesfield Dove Medical Press Limited 01.01.2021; Taylor & Francis Ltd; Dove
• Subjects: Biomarkers; Biopsy; Blood platelets; Bone marrow; Cancer; Cancer therapies; Cytoplasm; Development and progression; Diagnosis; Diagnostic equipment (Medical); Drug resistance; Exosomes; External stimuli; Gastric cancer; Genomes; Genomics; Health aspects; Hematology; Hematopoietic stem cells; Inflammation; Liver cancer; Lung cancer; Medical prognosis; Megakaryocytes; Metastases; Metastasis; Microenvironments; mRNA; Peripheral blood; Physiological aspects; Physiology; Platelets; Review; RNA; Stem cells; Survival analysis; Thyroid gland; Tumor microenvironment; Tumors; China

Due to the inherent molecular heterogeneity of metastatic tumours and the dynamic evolution ability of tumour genomes, tumour tissues obtained through biopsy and other methods cannot capture all of the features of tumour genomes. A new diagnostic concept called "liquid biopsy" has received...