Automated Recommendation of Research Keywords from PubMed That Suggest the Molecular Mechanism Associated with Biomarker Metabolites

• Published in: Metabolites Vol. 12; no. 2; p. 133
• Main Authors: Kanazawa, Shinji, Shimizu, Satoshi, Kajihara, Shigeki, Mukai, Norio, Iida, Junko, Matsuda, Fumio
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.02.2022; MDPI
• Subjects: Amino acids; Association analysis; Automation; biomarker discovery; Biomarkers; Carbon; Connectivity; Dehydrogenases; Diabetes; Disease; keyword recommendation; Keywords; Knowledge; Medical Subject Headings terms; MeSH co-occurrence; Metabolism; Metabolites; Metabolomics; Methods; Molecular modelling; Prostate cancer; Signal transduction; Software; Tumors; Medical Subject Headings terms; association analysis; biomarker discovery; keyword recommendation; MeSH co-occurrence

Metabolomics can help identify candidate biomarker metabolites whose levels are altered in response to disease development or drug administration. However, assessment of the underlying molecular mechanism is challenging considering it depends on the researcher’s knowledge. This study reports a novel...