A Sixty-Year Research and Development of Trichosanthin, a Ribosome-Inactivating Protein - Lu, Jia-Qi; Wong, Kam-Bo; Shaw, Pang-Chui (Toxins, 2022)
Keywords: abortifacient; Abortion; Amino acids; Animals; anti-cancer; anti-HIV; Binding sites; Colorectal cancer; Colorectal carcinoma; Crystal structure; Deactivation; Dextran; Dextrans; Drug dosages; E coli; Glycerol; Herbal medicine; HIV; Human immunodeficiency virus; Immune response; Immunotoxins; Lymphocytes; Macrophages; Mammalian cells; Mammals; Menstruation; N-Glycosylase; Pain; Polyethylene; Polyethylenes; Pregnancy complications; Prescriptions; Proteins; R&D; Rats; Research & development; Review; Ribosomal Proteins - chemistry; Ribosome-inactivating protein; Ribosomes; Ricin; rRNA 28S; rRNA N-glycosylase; Saporins; Side effects; Tian Hua Fen; Traditional Chinese medicine; Trichosanthin; Trichosanthin - chemistry; Trichosanthin - pharmacology; China; Tian Hua Fen; anti-HIV; immunotoxin; abortifacient; anti-cancer; rRNA N-glycosylase; trichosanthin