NaCl Inhibits Citrinin and Stimulates Monascus Pigments and Monacolin K Production

• Published in: Toxins Vol. 11; no. 2; p. 118
• Main Authors: Zhen, Zhixin, Xiong, Xiaoqian, Liu, Yingbao, Zhang, Jialan, Wang, Shaojin, Li, Li, Gao, Mengxiang
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15.02.2019; MDPI
• Subjects: Abiotic stress; Acid Phosphatase - metabolism; Alkaline phosphatase; Alkaline Phosphatase - metabolism; antioxidant; Antioxidants; Biosynthesis; Catalase; Catalase - metabolism; Citrinin; Citrinin - antagonists & inhibitors; Citrinin - metabolism; Cultivation; Dietary supplements; Enzymes; Fermentation; Fungi; Gene regulation; Genes; Glutathione; Glutathione - metabolism; growth; Lovastatin - metabolism; Metabolism; Metabolites; Monascus; Monascus - drug effects; Monascus - growth & development; Monascus - metabolism; Monascus purpureus; Mycelia; Phosphatase; Pigments; Pigments, Biological - metabolism; Reactive oxygen species; Reactive Oxygen Species - metabolism; Red pigments; Salt; Secondary Metabolism - drug effects; Secondary metabolites; Sodium chloride; Sodium Chloride - pharmacology; Superoxide dismutase; Superoxide Dismutase - metabolism; Synthesis; Toxins; Transcription; Monascus purpureus; antioxidant; citrinin; growth; secondary metabolites

Applications of beneficial secondary metabolites produced by Monascus purpureus (M. purpureus) could be greatly limited for citrinin, a kidney toxin. The link of NaCl with cell growth and secondary metabolites in M. purpureus was analyzed with supplementations of different concentrations of NaCl in...