Reactive Oxygen Species Are Central Mediators of Vascular Dysfunction and Hypertension Induced by Ethanol Consumption

• Published in: Antioxidants Vol. 12; no. 10; p. 1813
• Main Authors: Padovan, Júlio C, Dourado, Thales M. H, Pimenta, Gustavo F, Bruder-Nascimento, Thiago, Tirapelli, Carlos R
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 29.09.2023; MDPI
• Subjects: Acetaldehyde; Adipose tissue; Adipose tissues; Alcohol; Alcohol, Denatured; Alcoholism; Aldosterone; Angiotensin; Bioavailability; Blood pressure; Body mass index; Calcium (intracellular); Cardiovascular diseases; Corticosteroids; Endothelium; Enzymes; Ethanol; Gender; Hypertension; NAD(P)H oxidase; NADPH oxidase; NADPH-diaphorase; Niacinamide; Nitric oxide; Oxidases; Oxidative stress; Public health; Reactive oxygen species; Renin; Review; Risk factors; Australia

Consumption of high amounts of ethanol is a risk factor for development of cardiovascular diseases such as arterial hypertension. The hypertensive state induced by ethanol is a complex multi-factorial event, and oxidative stress is a pathophysiological hallmark of vascular dysfunction associated wit...